Development and validation of a liquid chromatography and ion spray tandem mass spectrometry method for the quantification of artesunate, artemether... (Publications)
Recently, promising fasciocidal activities of artesunate and artemether were described in rats and sheep. Therefore, a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to
Birth weight and carotid artery intima-media thickness (Publications)
OBJECTIVES: To determine the association between birth weight and carotid artery intima-media thickness (CIMT), a measure of atherogenesis, in a population of 11-year-old children.STUDY DESIGN: CIMT m
Impact of road traffic noise annoyance on health-related quality of life: results from a population-based study (Publications)
PURPOSE: To estimate the impact of traffic-related noise annoyance on health-related quality of life (HrQoL) in a population-based study and potential effect modification by gender. METHODS: The study
Time-activity relationships to VOC personal exposure factors (Publications)
Social and demographic factors have been found to play a significant role in differences between time-activity patterns of population subgroups. Since time-activity patterns largely influence personal
Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on... (Publications)
Trypanothione reductase (TR) is a flavoenzyme unique to trypanosomatid parasites and a target for lead discovery programs. Various inhibitor scaffolds have emerged in the past, exhibiting moderate aff
Field evaluation of a recombinant glutathione S-transferase-based pyrethroid quantification assay (Publications)
A recombinant glutathione S-transferase (GST)-based pyrethroid quantification assay was field-tested in Ifakara, Tanzania. Initial laboratory tests suggested that all reagents used in the assay should
Pan-dengue virus detection by PCR for travelers returning from the tropics (Publications)
We performed dengue virus (DENV) serology and quantitative real-time pan-DENV reverse transcription-PCR (RT-PCR) on 186 sera of 171 patients returning from the tropics. DENV loads significantly decrea
Symptoms and transmission of intestinal cryptosporidiosis (Publications)
Cryptosporidium spp are a cause of diarrhoea in toddlers. Symptoms and routes of transmission were investigated in a prospective case-control study in the city and surroundings of Basel, Switzerland.
Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in <em>Plasmodium falciparum</em> (Publications)
The malaria parasite Plasmodium falciparum undergoes antigenic variation to evade host immune responses through switching expression of variant surface proteins encoded by the var gene family. We demo
