Human macrophage responses to clinical isolates from the <em>Mycobacterium tuberculosis</em> complex discriminate between ancient and modern lineages (Publications)
The aim of the present study was to determine whether there is a correlation between phylogenetic relationship and inflammatory response amongst a panel of clinical isolates representative of the glob
Malaria transmission after five years of vector control on Bioko Island, Equatorial Guinea (Publications)
ABSTRACT: BACKGROUND: Malaria is endemic with year-round transmission on Bioko Island. The Bioko Island Malaria Control Project (BIMCP) started in 2004 with the aim to reduce malaria transmission and
The use of antenatal and postnatal care: perspectives and experiences of women and health care providers in rural southern Tanzania (Publications)
BACKGROUND: Although antenatal care coverage in Tanzania is high, worrying gaps exist in terms of its quality and ability to prevent, diagnose or treat complications. Moreover, much less is known abou
Design, implementation and evaluation of a national campaign to deliver 18 million free long-lasting insecticidal nets to uncovered sleeping spaces in... (Publications)
BACKGROUND: Since 2004, the Tanzanian National Voucher Scheme has increased availability and accessibility of insecticide-treated nets (ITNs) to pregnant women and infants by subsidizing the cost of n
Cost implications of improving malaria diagnosis: findings from north-eastern Tanzania (Publications)
BACKGROUND: Over diagnosis of malaria contributes to improper treatment, wastage of drugs and resistance to the few available drugs. This paper attempts to estimate the rates of over diagnosis of mala
Efficacy of sulfadoxine-pyrimethamine in Tanzania after two years as first-line drug for uncomplicated malaria: assessment protocol and implication... (Publications)
BACKGROUND: Systematic surveillance for resistant malaria shows high level of resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) across eastern and southern parts of Africa. This st
Behavioural determinants of gene flow in malaria vector population: <em>Anopheles gambiae</em> males select large females as mates (Publications)
BACKGROUND: Plasmodium-refractory mosquitoes are being rapidly developed for malaria control but will only succeed if they can successfully compete for mates when released into the wild. Pre-copulator
Identification of compounds with anti-proliferative activity against <em>Trypanosoma brucei brucei</em> strain 427 by a whole cell viability based HTS... (Publications)
Human African Trypanosomiasis (HAT) is caused by two trypanosome sub-species, Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Drugs available for the treatment of HAT have significant