Artesunate-mefloquine combination therapy in acute <em>Plasmodium falciparum</em> malaria in young children: a field study regarding neurological and... (Publications)
BACKGROUND: Mefloquine-artesunate combination therapy for uncomplicated falciparum malaria is one of the treatments used in African children. Data concerning neurological safety in adults and children
Frontiers of parasitology research in the People's Republic of China: infection, diagnosis, protection and surveillance (Publications)
ABSTRACT: Control and eventual elimination of human parasitic diseases in the People's Republic of China (P.R. China) requires novel approaches, particularly in the areas of diagnostics, mathematical
Do existing research summaries on health systems match immunisation managers' needs in middle- and low-income countries? Analysis of GAVI health... (Publications)
ABSTRACT: BACKGROUND: The GAVI Alliance was created in 2000 to increase access to vaccines. More recently, GAVI has supported evidence-based health systems strengthening to overcome barriers to vaccin
Implementing new health interventions in developing countries: why do we lose a decade or more? (Publications)
BACKGROUND: It is unclear how long it takes for health interventions to transition from research and development (R&D) to being used against diseases prevalent in resource-poor countries. We undertook
The interrelation between premenstrual syndrome and major depression: results from a population-based sample (Publications)
ABSTRACT: BACKGROUND: Research about the relationship between premenstrual syndrome (PMS) and major depression is limited. This study examined the relationship between moderate to severe PMS and major
On the origin of <em>Mycobacterium ulcerans</em>, the causative agent of Buruli ulcer (Publications)
ABSTRACT: BACKGROUND: Mycobacterium ulcerans is an unusual bacterial pathogen with elusive origins. While closelyrelated to the aquatic dwelling M. marinum, M. ulcerans has evolved the ability to prod
Time to move from presumptive malaria treatment to laboratory-confirmed diagnosis and treatment in African children with fever (Publications)
BACKGROUND TO THE DEBATE: Current guidelines recommend that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub
Simulated impact of RTS,S/AS01 vaccination programs in the context of changing malaria transmission (Publications)
INTRODUCTION: The RTS,S/AS01 pre-erythrocytic malaria vaccine is in phase III clinical trials. It is critical to anticipate where and how it should be implemented if trials are successful. Such planni
Viral hepatitis and rapid diagnostic test based screening for HBsAg in HIV-infected patients in rural Tanzania (Publications)
BACKGROUND: Co-infection with hepatitis B virus (HBV) is highly prevalent in people living with HIV in Sub-Saharan Africa. Screening for HBV surface antigen (HBsAg) before initiation of combination an
Design, implementation and evaluation of a national campaign to distribute nine million free LLINs to children under five years of age in Tanzania (Publications)
ABSTRACT: BACKGROUND: After a national voucher scheme in 2004 provided pregnant women and infants with highly subsidized insecticide-treated nets (ITNs), use among children under five years (U5s) in m
