Identification of new human malaria parasite <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase inhibitors by pharmacophore and... (Publications)
Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH), a key enzyme in the de novo pyrimidine biosynthesis pathway, which the Plasmodium falciparum relies on exclusively for survival, has emerg
Reaching the surveillance-response stage of schistosomiasis control in the People's Republic of China: a modelling approach (Publications)
With the goal set to eliminate schistosomiasis nationwide by 2020, The People's Republic of China has initiated the surveillance-response stage to identify remaining sources of infection and potential
Bimodal X-ray and infrared imaging of an organometallic derivative of praziquantel in <em>Schistosoma mansoni</em> (Publications)
An organometallic derivative of praziquantel was studied directly in worms, using ICP-MS for quantification and synchrotron based imaging. X-Ray fluorescence and IR absorption microspectroscopy, were
Absolute quantification of the host-to-parasite DNA ratio in <em>Theileria parva</em>-infected lymphocyte cell lines (Publications)
Theileria parva is a tick-transmitted intracellular apicomplexan pathogen of cattle in sub-Saharan Africa that causes East Coast fever (ECF). ECF is an acute fatal disease that kills over one million
DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis (Publications)
Epigenetic modifications, including DNA methylation, represent a potential mechanism for environmental impacts on human disease. Maternal smoking in pregnancy remains an important public health proble
Utilization of health care services among internal migrants in Hanoi and its correlation with health insurance: a cross-sectional study (Publications)
BACKGROUND: Economic transition (DoiMoi) in the 1980s in Viet Nam has led to internal migration, particularly rural-to-urban migration. Many studies suggested that there is a difference between non-mi
What we breathe impacts our health: improving understanding of the link between air pollution and health (Publications)
Air pollution contributes to the premature deaths of millions of people each year around the world, and air quality problems are growing in many developing nations. While past policy efforts have succ
<em>Plasmodium falciparum Plasmodium</em> helical interspersed subtelomeric proteins contribute to cytoadherence and anchor <em>P. falciparum</em>... (Publications)
Adherence of Plasmodium falciparum infected erythrocytes to host endothelium is conferred through the parasite-derived virulence factor PfEMP1, the major contributor to malaria severity. PfEMP1 locate
New derivatives of bicyclic diamines with antiprotozoal activity (Publications)
omega-Aminoacyl and -alkyl derivatives of 4-(dialkylamino)bicyclo[2.2.2]octan-2-amines and of 5-(dialkylamino)-2-azabicyclo[3.2.2]nonanes were prepared and their activities were examined in vitro agai
Prophylactic effect of artemether on human <em>Schistosomiasis mansoni</em> among Egyptian children: a randomized controlled trial (Publications)
A double-blind, randomized controlled trial was conducted in an endemic focus for Schistosoma mansoni in Kafr El-Sheikh Governorate, Northern Nile Delta, Egypt, to evaluate the prophylactic effect of
