Combining 4-aminoquinoline- and clotrimazole-based pharmacophores toward innovative and potent hybrid antimalarials (Publications)
Antimalarial agents structurally based on novel pharmacophores, synthesized by low-cost synthetic procedures and characterized by low potential for developing resistance are urgently needed. Recently,
Prospective study of a serogroup X <em>Neisseria meningitidis </em>outbreak in northern Ghana (Publications)
After an epidemic of serogroup A meningococcal meningitis in northern Ghana, a gradual disappearance of the epidemic strain was observed in a series of five 6-month carriage surveys of 37 randomly sel
Childhood asthma and exposure to traffic and nitrogen dioxide (Publications)
BACKGROUND: Evidence for a causal relationship between traffic-related air pollution and asthma has not been consistent across studies, and comparisons among studies have been difficult because of the
Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation (Publications)
Mycolactone is a diffusible lipid secreted by the human pathogen Mycobacterium ulcerans, which induces the formation of open skin lesions referred to as Buruli ulcers. Here, we show that mycolactone o
Chemometric and biological validation of a capillary electrophoresis metabolomic experiment of <em>Schistosoma mansoni</em> infection in mice (Publications)
Metabonomic and metabolomic studies are increasingly utilized for biomarker identification in different fields, including biology of infection. The confluence of improved analytical platforms and the
Antiparasitic compounds from <em>Cupania cinerea</em> with activities against <em>Plasmodium falciparum</em> and <em>Trypanosoma brucei... (Publications)
In a survey of plants from Ecuador with antiprotozoal activity, Cupania cinerea was found to show significant in vitro activity against the Plasmodium falciparum K1 strain and Trypanosoma brucei rhode
Global burden of human food-borne trematodiasis: a systematic review and meta-analysis (Publications)
BACKGROUND: Food-borne trematodiases are a group of neglected tropical diseases caused by liver, lung, and intestinal parasitic fluke infections. As part of the Global Burden of Diseases, Injuries, an
Receiving the diagnosis of lung cancer: patient recall of information and satisfaction with physician communication (Publications)
PURPOSE: Little is known about the information newly diagnosed patients with lung cancer recall and how satisfied they are with physicians' communication. PATIENTS AND METHODS: Seventy-one consecutive