Artemether administered together with hemin damages schistosomes in vitro (Publications)
We conducted experiments in vitro to assess the effect of artemether in combination with haemin on adult Schistosoma japonicum, S. mansoni and S. haematobium. When schistosomes were maintained in a me
Evaluation of the "future non-smokers" campaign of the Swiss Society of Pharmacists (Publications)
In order to promote low threshold smoking cessation, a campaign was organized by the Swiss Society of Pharmacists in 616 Swiss pharmacies. The evaluation of this project took into consideration the ac
Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of <em>Plasmodium falciparum</em>... (Publications)
BACKGROUND: Two single-point mutations of the Plasmodium falciparum cytochrome b gene (Tyr268Asn and Tyr268Ser) were recently reported in cases of atovaquone/proguanil (Malarone) treatment failure. Ho
Severe dengue virus infection in travelers: risk factors and laboratory indicators (Publications)
BACKGROUND: Dengue fever is the most common arboviral disease in travelers. In countries where dengue virus is endemic, sequential (secondary) infections with different dengue virus serotypes are asso
A new single nucleotide polymorphism in the insulin-like growth factor I regulatory region associates with colorectal cancer risk in singapore chinese (Publications)
Elevated levels of plasma insulin-like growth factor I (IGF-I) are a potential risk factor for several cancers, including colorectal cancer. Physiologic levels of plasma IGF-I vary greatly; this varia
Detailed characterization and profiles of crankcase and diesel particulate matter exhaust emissions using speciated organics (Publications)
A monitoring campaign was conducted in August-September 2005 to compare different experimental approaches quantifying school bus self-pollution. As part of this monitoring campaign, a detailed charact
Research and development of antischistosomal drugs in the People's Republic of China a 60-year review (Publications)
A comprehensive 60-year review of antischistosomal drug discovery and development research in the People's Republic of China (P.R. China) is presented. In the 1950s, three antimonials were developed,
Characterization of the two major CYP450 metabolites of ozonide (1,2,4-trioxolane) OZ277 (Publications)
The antimalarial synthetic ozonide OZ277 (RBx11160) was hydroxylated by human liver microsomes at the distal bridgehead carbon atoms of the spiroadamantane substructure to form two carbinol metabolite
