Long-lasting and fast-acting<em> in vivo</em> efficacious antiplasmodial azepanylcarbazole amino alcohol (Publications)
With approximately 429,000 deaths in 2016, malaria remains a major infectious disease where the need to treat the fever symptoms, but also to provide relevant post-treatment prophylaxis, is of major i
Jozilebomines A and B, naphthylisoquinoline dimers from the Congolese liana <em>Ancistrocladus ileboensis</em>, with antiausterity activities against... (Publications)
Two new naphthylisoquinoline dimers, jozilebomines A (1a) and B (1b), were isolated from the roots of the Congolese plant Ancistrocladus ileboensis, along with the known dimer jozimine A2 (2). These c
<em>Strongyloides stercoralis</em> is associated with significant morbidity in rural Cambodia, including stunting in children (Publications)
BACKGROUND: Strongyloides stercoralis is a soil-transmitted nematode that can replicate within its host, leading to long-lasting and potentially fatal infections. It is ubiquitous and highly prevalent
The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing (Publications)
Kinetoplastid parasites-trypanosomes and leishmanias-infect millions of humans and cause economically devastating diseases of livestock, and the few existing drugs have serious deficiencies. Benzoxabo