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1. Association of carotide strain and prior of cardiovascular disease - results from the Swiss Air Pollution and Lung and Heart Disease in Adults Cohort... (Publications)

   Association of carotide strain and prior of cardiovascular disease - results from the Swiss Air Pollution and Lung and Heart Disease in Adults Cohort Study (SAPALDIA3)

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2. Marc Humbert discusses lung function and long-term air pollution exposure with Prof. Nicole Probst-Hensch (Publications)

   Marc Humbert discusses lung function and long-term air pollution exposure with Prof. Nicole Probst-Hensch

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3. Common SIRT1 variants modify the effect of abdominal adipose tissue on aging-related lung function decline (Publications)

   Common SIRT1 variants modify the effect of abdominal adipose tissue on aging-related lung function decline

   Relevance:

   Lung function is an independent predictor of mortality and serves as an aging marker in never smokers. The protein sirtuin-1 of gene SIRT1 has profound anti-inflammatory effects and regulates metaboli

4. Premature atrial contractions in the general population: frequency and risk factors (Publications)

   Premature atrial contractions in the general population: frequency and risk factors

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   BACKGROUND: Premature atrial contractions (PACs) are independent predictors of atrial fibrillation, stroke and death. However, little is known about PAC frequency in the general population and its ass

5. Land use regression models for crustal and traffic-related PM2.5 constituents in four areas of the SAPALDIA study (Publications)

   Land use regression models for crustal and traffic-related PM2.5 constituents in four areas of the SAPALDIA study

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   Many studies have documented adverse health effects of long-term exposure to fine particulate matter (PM2.5), but there is still limited knowledge regarding the causal relationship between specific so

6. A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order (Publications)

   A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order

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   BACKGROUND: Hay fever or seasonal allergic rhinitis (AR) is a chronic disorder associated with IgE sensitization to grass. The underlying genetic variants have not been studied comprehensively. There

7. Genetic heterogeneity of asthma phenotypes identified by a clustering approach (Publications)

   Genetic heterogeneity of asthma phenotypes identified by a clustering approach

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   The aim was to identify genetic variants associated with refined asthma phenotypes enabling to take into account multiple features of the disease.Latent class analysis (LCA) was applied in 3001 adults

8. Traffic-related air pollution correlates with adult-onset asthma among never-smokers (Publications)

   Traffic-related air pollution correlates with adult-onset asthma among never-smokers

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   BACKGROUND: Traffic-related pollution is associated with asthma onset in children. Its effect on adult-onset asthma is poorly investigated. OBJECTIVE: We used the SAPALDIA cohort study to investigate

9. Reduced exposure to PM10 and attenuated age-related decline in lung function (Publications)

   Reduced exposure to PM10 and attenuated age-related decline in lung function

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   BACKGROUND: Air pollution has been associated with impaired health, including reduced lung function in adults. Moving to cleaner areas has been shown to attenuate adverse effects of air pollution on l

10. Development of land use regression models for nitrogen dioxide, ultrafine particles, lung deposited surface area, and four other markers of... (Publications)

    Development of land use regression models for nitrogen dioxide, ultrafine particles, lung deposited surface area, and four other markers of particulate matter pollution in the Swiss SAPALDIA regions

    Relevance:

    BACKGROUND: Land Use Regression (LUR) is a popular method to explain and predict spatial contrasts in air pollution concentrations, but LUR models for ultrafine particles, such as particle number conc