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1. Local cellular immune responses and pathogenesis of Buruli ulcer lesions in the experimental <em>Mycobacterium ulcerans</em> pig infection model (Publications)

   Local cellular immune responses and pathogenesis of Buruli ulcer lesions in the experimental <em>Mycobacterium ulcerans</em> pig infection model

   Relevance:

   BACKGROUND: Buruli ulcer is a neglected tropical disease of the skin that is caused by infection with Mycobacterium ulcerans. We recently established an experimental pig (Sus scrofa) infection model f

2. Local heat application for the treatment of Buruli ulcer: results of a phase II open label single center non comparative clinical trial (Publications)

   Local heat application for the treatment of Buruli ulcer: results of a phase II open label single center non comparative clinical trial

   Relevance:

   BACKGROUND: Buruli ulcer (BU) is a necrotising skin disease most prevalent among West African children. The causative organism, Mycobacterium ulcerans, is sensitive to temperatures above 37 degrees C.

3. Effectiveness of a home-based counselling strategy on neonatal care and survival: a cluster-randomised trial in six districts of rural southern... (Publications)

   Effectiveness of a home-based counselling strategy on neonatal care and survival: a cluster-randomised trial in six districts of rural southern Tanzania

   Relevance:

   BACKGROUND: We report a cluster-randomised trial of a home-based counselling strategy, designed for large-scale implementation, in a population of 1.2 million people in rural southern Tanzania. We hyp

4. Exploration of DAPI analogues: synthesis, antitrypanosomal activity, DNA binding and fluorescence properties (Publications)

   Exploration of DAPI analogues: synthesis, antitrypanosomal activity, DNA binding and fluorescence properties

   Relevance:

5. Spatial distribution of <em>Mycobacterium ulcerans</em> in Buruli ulcer lesions: implications for laboratory diagnosis (Publications)

   Spatial distribution of <em>Mycobacterium ulcerans</em> in Buruli ulcer lesions: implications for laboratory diagnosis

   Relevance:

   BACKGROUND: Current laboratory diagnosis of Buruli ulcer (BU) is based on microscopic detection of acid fast bacilli, quantitative real-time PCR (qPCR), histopathology or cultivation. Insertion sequen

6. Comparative study of activities of a diverse set of anti-mycobacterial agents against <em>Mycobacterium tuberculosis</em> and <em>Mycobacterium... (Publications)

   Comparative study of activities of a diverse set of anti-mycobacterial agents against <em>Mycobacterium tuberculosis</em> and <em>Mycobacterium ulcerans</em>

   Relevance:

   A library of compounds covering a broad chemical space was selected from a tuberculosis drug development program and screened in a whole cell assay against Mycobacterium ulcerans, the causative agent

7. Wayanin and guaijaverin, two active metabolites found in a <em>Psidium acutangulum</em> Mart. ex DC (syn. P. persoonii McVaugh) (Myrtaceae)... (Publications)

   Wayanin and guaijaverin, two active metabolites found in a <em>Psidium acutangulum</em> Mart. ex DC (syn. P. persoonii McVaugh) (Myrtaceae) antimalarial decoction from the Wayana Amerindians

   Relevance:

   ETHNOPHARMACOLOGICAL RELEVANCE: Psidium acutangulum Mart. ex DC is a small tree used by the Wayana Amerindians from the Upper-Maroni in French Guiana for the treatment of malaria. AIM OF THE STUDY: In

8. Long-term air pollution and traffic noise exposures and mild cognitive impairment in older adults: a cross-sectional analysis of the Heinz Nixdorf... (Publications)

   Long-term air pollution and traffic noise exposures and mild cognitive impairment in older adults: a cross-sectional analysis of the Heinz Nixdorf recall study

   Relevance:

   BACKGROUND: Mild cognitive impairment (MCI) describes the intermediate state between normal cognitive aging and dementia. Adverse effects of air pollution (AP) on cognitive functions have been propose

9. Timing of antenatal care for adolescent and adult pregnant women in south-eastern Tanzania (Publications)

   Timing of antenatal care for adolescent and adult pregnant women in south-eastern Tanzania

   Relevance:

   ABSTRACT: BACKGROUND: Early and frequent antenatal care attendance during pregnancy is important to identify and mitigate risk factors in pregnancy and to encourage women to have a skilled attendant a

10. Correction: a bundle of services increased ascertainment of Tuberculosis among HIV-infected individuals enrolled in a HIV cohort in rural sub-Saharan... (Publications)

    Correction: a bundle of services increased ascertainment of Tuberculosis among HIV-infected individuals enrolled in a HIV cohort in rural sub-Saharan Africa

    Relevance: