Research capacity strengthening in low and middle income countries - an evaluation of the WHO/TDR career development fellowship programme (Publications)
Between August 2012 and April 2013 the Career Development Fellowship programme of the Special Programme for Research and Training in Tropical Diseases (World Health Organization) underwent an external
Independent loss of immunogenic proteins in <em>Mycobacterium ulcerans</em> suggests immune evasion (Publications)
The highly immunogenic mycobacterial proteins ESAT-6, CFP-10, and HspX represent potential target antigens for the development of subunit vaccines and immunodiagnostic tests. Recently, the complete ge
Risk factors for Buruli ulcer in Ghana - a case control study in the Suhum-Kraboa-Coaltar and Akuapem south districts of the eastern region (Publications)
BACKGROUND: Buruli ulcer (BU) is a skin disease caused by Mycobacterium ulcerans. Its exact mode of transmission is not known. Previous studies have identified demographic, socio-economic, health and
AAA proteases of mitochondria: quality control of membrane proteins and regulatory functions during mitochondrial biogenesis (Publications)
An ubiquitous and conserved proteolytic system regulates the stability of mitochondrial inner membrane proteins. Two AAA proteases with catalytic sites at opposite membrane surfaces form a membrane-in
Activity of tribendimidine and praziquantel combination therapy against the liver fluke <em>Opisthorchis viverrini</em> <em>in vitro</em> and <em>in... (Publications)
Opisthorchiasis, caused by the liver fluke Opisthorchis viverrini, a food-borne trematode, is an important public health problem; however, only a single drug, praziquantel is available. We investigate
PCR diagnosis of <em>Opisthorchis viverrini</em> and <em>Haplorchis taichui</em> infections in a Lao community in an area of endemicity and comparison... (Publications)
Opisthorchiasis is a major public health problem in Southeast Asia. Affected individuals often have mixed infections with the liver fluke Opisthorchis viverrini and minute intestinal flukes such as Ha
Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, tribendimidine, and praziquantel in patients with <em>Opisthorchis... (Publications)
BACKGROUND: Praziquantel is the only drug available for treatment of Opisthorchis viverrini, although in-vivo studies point to activity of mefloquine, artesunate, and tribendimidine against this liver