Costs and cost-effectiveness of <em>Plasmodium vivax </em>control (Publications)
The continued success of efforts to reduce the global malaria burden will require sustained funding for interventions specifically targeting Plasmodium vivax The optimal use of limited financial resou
Gametocyte carriage in uncomplicated <em>Plasmodium falciparum</em> malaria following treatment with artemisinin combination therapy: a systematic... (Publications)
BACKGROUND: Gametocytes are responsible for transmission of malaria from human to mosquito. Artemisinin combination therapy (ACT) reduces post-treatment gametocyte carriage, dependent upon host, paras
Identification of a potential antimalarial drug candidate from a series of 2-aminopyrazines by optimization of aqueous solubility and potency across... (Publications)
Introduction of water-solubilizing groups on the 5-phenyl ring of a 2-aminopyrazine series led to the identification of highly potent compounds against the blood life-cycle stage of the human malaria
Validating the children's depression inventory in the context of Rwanda (Publications)
BACKGROUND: Depression is often co-morbid with chronic conditions, and when combined with HIV it can increase progression and reduce survival. A brief and accurate screening tool for depression among
Efficacy of moxidectin versus ivermectin against <em>Strongyloides stercoralis</em> infections: a randomized controlled non-inferiority trial (Publications)
Background: Infections with Strongyloides stercoralis are of considerable public health relevance. Moxidectin, a well-established drug in veterinary medicine under consideration for regulatory submiss
Disease burden due to gastrointestinal infections among people living along the major wastewater system in Hanoi, Vietnam (Publications)
Background: Despite recent improvements of wastewater treatment capacities in urban areas of Hanoi, Vietnam, microbial pollution is still considerable. There is a paucity of burden estimates due to ga
Preventive chemotherapy in one year reduces by over 80% the number of individuals with soil-transmitted helminthiases causing morbidity: results from... (Publications)
The morbidity due to Ascaris lumbricoides and Trichuris trichiura is caused by infections of moderate and heavy intensity while hookworm infections of all intensities are recognized to cause morbidity