Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (Publications)
Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for est
Long-term air pollution exposure and diabetes in a population-based Swiss cohort (Publications)
Air pollution is an important risk factor for global burden of disease. There has been recent interest in its possible role in the etiology of diabetes mellitus. Experimental evidence is suggestive, b
Modifying effect of a common polymorphism in the interleukin-6 promoter on the relationship between long-term exposure to traffic-related particulate... (Publications)
BACKGROUND: Exposure to particulate matter (PM) has been associated with an increase in many inflammatory markers, including interleukin 6 (IL6). Air pollution exposure has also been suggested to indu
Rhinitis in Swiss adults is associated with asthma and early life factors, but not second hand tobacco smoke or obesity (Publications)
BACKGROUND: Second hand tobacco smoke (SHS) and overweight/obesity are risk factors for asthma and lower airway respiratory symptoms. We investigated whether SHS or overweight/obesity were also associ
Is there a differential impact of parity on blood pressure by age? (Publications)
OBJECTIVE: In pregnancy, women experience metabolic and hemodynamic changes of potential long-term impact. Conflicting evidence exists on the impact on blood pressure (BP). We investigated the associa