Reliability of functional connectivity of EEG applying microstates-segmented versus classical calculation of phase lag index (Publications)
BACKGROUND: Connectivity analysis characterizes normal and altered brain function, e.g. using the phase lag index (PLI), which is based on phase relations. However, reliability of PLI over time is lim
Drug resistance mutations after the first 12 months on antiretroviral therapy and determinants of virologic failure in Rwanda (Publications)
OBJECTIVE: To evaluate HIV drug resistance (HIVDR) and determinants of virological failure in a large cohort of patients receiving first-line tenofovir-based antiretroviral (ART) regimens. METHODS: A
Quinolone amides as anti-trypanosomal lead compounds with in vivo activity (Publications)
Human African Trypanosomiasis (HAT) is a major tropical disease with few available drugs for treatment driving the need for novel active compounds. Recently, morpholino-substituted benzyl amides of th
Ambiguous care: siblings and the economies of HIV-related care in Zambia (Publications)
While kinship used to be considered a backbone of the creation of mutual obligations for care in pre-industrial societies, economic and social change has altered how care is provided. Notwithstanding
How to evaluate health-related quality of life and its association with medication adherence in pulmonary tuberculosis - designing a prospective... (Publications)
INTRODUCTION: Health-related quality of life (HRQOL) has become an important measure to identify and shape effective and patient-relevant healthcare interventions innovations through outcomes. Adheren
The prevalence of syphilis infection and its associated factors in the general population of Rwanda: a national household-based survey (Publications)
Background. The prevalence of syphilis among HIV-infected people is a public health concern, but there is limited literature to describe the true burden of syphilis in resource-limited settings. We co
Gift from nature: cyclomarin a kills mycobacteria and malaria parasites by distinct modes of action (Publications)
Malaria continues to be one of the most devastating human diseases despite many efforts to limit its spread by prevention of infection or by pharmaceutical treatment of patients. We have conducted a s
Discovery and optimisation studies of antimalarial phenotypic hits (Publications)
There is an urgent need for the development of new antimalarial compounds. As a result of a phenotypic screen, several compounds with potent activity against the parasite Plasmodium falciparum were id
Outcomes mapping study for childhood vaccination communication: too few concepts were measured in too many ways (Publications)
OBJECTIVES: The objectives of this paper are: 1) to comprehensively catalogue outcomes measured in trials of childhood vaccination communication interventions; and 2) to analyse patterns and trends in
