Fecal colonization with multidrug-resistant <em>E. coli</em> among healthy infants in rural Bangladesh (Publications)
Third generation cephalosporins (3GC) are one of the main choices for treatment of infections caused by multidrug-resistant (MDR) Gram-negative bacteria. Due to their overuse, an increasing trend of r
Insights into the genetic diversity of <em>Mycobacterium tuberculosis</em> in Tanzania (Publications)
BACKGROUND: Human tuberculosis (TB) is caused by seven phylogenetic lineages of the Mycobacterium tuberculosis complex (MTBC), Lineage 1-7. Recent advances in rapid genotyping of MTBC based on single
Antibiotic-resistant <em>Escherichia coli</em> in drinking water samples from rural Andean households in Cajamarca, Peru (Publications)
Antibiotic resistance in pathogenic bacteria is a serious public health issue. The growing threat is a cause for concern and action to prevent the emergence of new resistant strains and the spread of
Effects of a partially supervised conditioning programme in cystic fibrosis: an international multi-centre randomised controlled trial (ACTIVATE-CF):... (Publications)
BACKGROUND: Physical activity (PA) and exercise have become an accepted and valued component of cystic fibrosis (CF) care. Regular PA and exercise can positively impact pulmonary function, improve phy
Effect of immediate initiation of antiretroviral treatment on the risk of acquired HIV drug resistance (Publications)
OBJECTIVE: We estimated and compared the risk of clinically identified acquired drug resistance under immediate initiation [the currently recommended antiretroviral therapy (ART) initiation strategy],
Community knowledge, perceptions and attitudes regarding leprosy in rural Cameroon: the case of Ekondotiti and Mbonge health districts in the... (Publications)
BACKGROUND: Although leprosy is one of the oldest diseases known to humanity, it remains largely misunderstood. Misconceptions about leprosy leads to stigma towards people with the disease. This study
Development of a focused library of triazole-linked privileged-structure-based conjugates leading to the discovery of novel phenotypic hits against... (Publications)
Protozoan infections caused by Plasmodium, Leishmania, and Trypanosoma spp. contribute significantly to the burden of infectious diseases worldwide, causing severe morbidity and mortality. The inadequ
Candidate-gene based GWAS identifies reproducible DNA markers for metabolic pyrethroid resistance from standing genetic variation in East African... (Publications)
Metabolic resistance to pyrethroid insecticides is widespread in Anopheles mosquitoes and is a major threat to malaria control. DNA markers would aid predictive monitoring of resistance, but few mutat