Variability of reproductive history across the Swiss SAPALDIA cohort - Pattern and main determinants (Publications)
Background: Reproductive characteristics play an aetiological role for many diseases, including reproductive cancers. They have been shown to vary internationally and nationally, but have not yet been
A common functional variant on the pro-inflammatory Interleukin-6 gene may modify the association between long-term PM10 exposure and diabetes (Publications)
BACKGROUND: Air pollutants have been linked to type 2 diabetes (T2D), hypothesized to act through inflammatory pathways and may induce interleukin-6 gene (IL6) in the airway epithelium. The cytokine i
Premature atrial contractions in the general population: frequency and risk factors (Publications)
BACKGROUND: Premature atrial contractions (PACs) are independent predictors of atrial fibrillation, stroke and death. However, little is known about PAC frequency in the general population and its ass
Land use regression models for crustal and traffic-related PM2.5 constituents in four areas of the SAPALDIA study (Publications)
Many studies have documented adverse health effects of long-term exposure to fine particulate matter (PM2.5), but there is still limited knowledge regarding the causal relationship between specific so
Common SIRT1 variants modify the effect of abdominal adipose tissue on aging-related lung function decline (Publications)
Lung function is an independent predictor of mortality and serves as an aging marker in never smokers. The protein sirtuin-1 of gene SIRT1 has profound anti-inflammatory effects and regulates metaboli
Simulation of population-based commuter exposure to NO2 using different air pollution models (Publications)
We simulated commuter routes and long-term exposure to traffic-related air pollution during commute in a representative population sample in Basel (Switzerland), and evaluated three air pollution mode
Long-term exposure to air pollution and cardiovascular mortality: an analysis of 22 european cohorts (Publications)
BACKGROUND: Air pollution has been associated with cardiovascular mortality, but it remains unclear as to whether specific pollutants are related to specific cardiovascular causes of death. Within the
Arterial blood pressure and long-term exposure to traffic-related air pollution: an analysis in the European Study of Cohorts for Air Pollution... (Publications)
BACKGROUND: Long-term exposure to air pollution is hypothesized to elevate arterial blood pressure (BP). The existing evidence is scarce and country-specific. OBJECTIVES: We investigated the cross-sec
Cross-sectional associations between air pollution and chronic bronchitis: an ESCAPE meta-analysis across five cohorts (Publications)
BACKGROUND: This study aimed to assess associations of outdoor air pollution on prevalence of chronic bronchitis symptoms in adults in five cohort studies (Asthma-E3N, ECRHS, NSHD, SALIA, SAPALDIA) pa
Development of land use regression models for particle composition in twenty study areas in Europe (Publications)
Land Use Regression (LUR) models have been used to describe and model spatial variability of annual mean concentrations of traffic related pollutants such as nitrogen dioxide (NO2), nitrogen oxides (N
