Overview: development of drugs against<em> Mycobacterium ulcerans</em> (Publications)
For many years, wide margin surgical excision of Buruli ulcer lesions has been the main approach for the treatment of Mycobacterium ulcerans disease. The WHO now recommends an eight-week course of ora
Overview: mycolactone, the macrolide toxin of <em>Mycobacterium ulcerans</em> (Publications)
The acquisition by a Mycobacterium marinum-like progenitor of a plasmid encoding enzymes for the biosynthesis of the highly potent macrolide toxin mycolactone has set off the evolution of M. ulcerans
Overview: <em>Mycobacterium ulcerans </em>disease (Buruli ulcer) (Publications)
Enhanced international research efforts since the establishment of the Global BU Initiative in 1998 by the WHO have helped to advance our understanding of the epidemiology, and pathogenesis of Mycobac
Clinical diversity and treatment results in tegumentary leishmaniasis: a European clinical report in 459 patients (Publications)
BACKGROUND: Cutaneous leishmaniasis (CL) is frequent in travellers and can involve oro-nasal mucosae. Clinical presentation impacts therapeutic management. METHODOLOGY: Demographic and clinical data f
Measuring financial burden in families of children living with life-limiting conditions: a scoping review of cost indicators and outcome measures (Publications)
Objectives: This study aimed to provide a comprehensive overview of cost indicators and outcome measures used to measure financial burden in families of children with life-limiting conditions. Methods
The Swiss Tropical and Public Health Institute: past, present and future (Publications)
Compared internationally, the history of the Swiss Tropical and Public Health Institute (Swiss TPH) is unusual. Founded in 1944, at a time of utmost isolation, it was a response to specific needs of t
Global estimates of the implications of COVID-19-related preprimary school closures for children's instructional access, development, learning, and... (Publications)
Observational data collected prior to the pandemic (between 2004 and 2019) were used to simulate the potential consequences of early childhood care and education (ECCE) service closures on the estimat
Discovery and structure-activity relationships of quinazolinone-2-carboxamide derivatives as novel orally efficacious antimalarials (Publications)
A phenotypic high-throughput screen allowed discovery of quinazolinone-2-carboxamide derivatives as a novel antimalarial scaffold. Structure-activity relationship studies led to identification of a po
The effect of exposure to radiofrequency fields on cancer risk in the general and working population: a protocol for a systematic review of human... (Publications)
BACKGROUND: The World Health Organization (WHO) has an ongoing project to assess potential health effects of exposure to radiofrequency electromagnetic fields (RF-EMF) in the general and working popul