Pharmacometric analysis of tribendimidine mono- and combination therapies to achieve high cure rates in patients with hookworm infections (Publications)
To treat hookworm infections, pharmacotherapy has been only moderately successful and drug resistance is a threat. Therefore, novel treatment options including combination therapies should be consider
Population pharmacokinetics and exposure-response analysis of tribendimidine to improve treatment for children with hookworm infection (Publications)
Tribendimidine has been successful in treating hookworm infections and may serve as alternative to albendazole should resistance arise. Our aims were to (i) characterize the pharmacokinetics (PK) of t
Latent tuberculosis infection prevalence in rural Madagascar (Publications)
BACKGROUND: Understanding latent Mycobacterium tuberculosis infection (LTBI) prevalence is crucial for the design of TB control strategies. There are no data on LTBI in rural Madagascar. METHODS: Tube
Alpine Holocene tree-ring dataset: age-related trends in the stable isotopes of cellulose show species-specific patterns (Publications)
Stable isotopes in tree-ring cellulose are important tools for climatic reconstructions even though their interpretation could be challenging due to nonclimate signals, primarily those related to tree
Rationale and design of repeated cross-sectional studies to evaluate the reporting quality of trial protocols: the Adherence to SPIrit REcommendations... (Publications)
BACKGROUND: Clearly structured and comprehensive protocols are an essential component to ensure safety of participants, data validity, successful conduct, and credibility of results of randomized clin
Introduction to a landscape analysis of multisectoral approaches for prevention and control of infectious and vector-borne diseases (Publications)
The Swiss Development Cooperation, Canada's International Development Research Centre, the Swiss Tropical Public Health Institute, and the UNICEF/United Nations Development Programme (UNDP)/World Bank
Capture-based enrichment of <em>Theileria parva </em>DNA enables full genome assembly of first buffalo-derived strain and reveals exceptional... (Publications)
Theileria parva is an economically important, intracellular, tick-transmitted parasite of cattle. A live vaccine against the parasite is effective against challenge from cattle-transmissible T. parva
Epidemiological and health systems implications of evolving HIV and hypertension in South Africa and Kenya (Publications)
Health systems in sub-Saharan Africa are facing an ongoing HIV epidemic and increasing burden of noncommunicable disease. With the focus shifting to the development of comprehensive primary health car