Safety and efficacy of the 10-day melarsoprol schedule for the treatment of second stage rhodesiense sleeping sickness (Publications)
OBJECTIVE: Assessment of the safety and efficacy of a 10-day melarsoprol schedule in second stage T.b. rhodesiense patients and the effect of suramin-pretreatment on the incidence of encephalopathic s
Mefloquine - an aminoalcohol with promising antischistosomal properties in mice (Publications)
BACKGROUND: The treatment and control of schistosomiasis, an often neglected tropical disease that exacerbates poverty, depends on a single drug, praziquantel. The large-scale use of praziquantel migh
Differential patterns of infection and disease with <em>P. falciparum</em> and <em>P. vivax</em> in young Papua New Guinean children (Publications)
BACKGROUND: Where P. vivax and P. falciparum occur in the same population, the peak burden of P. vivax infection and illness is often concentrated in younger age groups. Experiences from malaria thera
Multiplicity and diversity of <em>Plasmodium vivax</em> infections in a highly endemic region in Papua New Guinea (Publications)
Plasmodium vivax is highly endemic in the lowlands of Papua New Guinea and accounts for a large proportion of the malaria cases in children less than 5 years of age. We collected 2117 blood samples at
Modelling the epidemiological impact of intermittent preventive treatment against malaria in infants (Publications)
BACKGROUND: Trials of intermittent preventive treatment against malaria in infants (IPTi) using sulphadoxine-pyrimethamine (SP) have shown a positive, albeit variable, protective efficacy against clin
MalHaploFreq: a computer programme for estimating malaria haplotype frequencies from blood samples (Publications)
BACKGROUND: Molecular markers, particularly those associated with drug resistance, are important surveillance tools that can inform policy choice. People infected with falciparum malaria often contain
Measurement of overall insecticidal effects in experimental hut trials (Publications)
ABSTRACT: BACKGROUND: The 'overall insecticidal effect' is a key measure used to evaluate public health pesticides for indoor use in experimental hut trials. It depends on the proportion of mosquitoes
Bayesian geostatistical modeling of Malaria Indicator Survey data in Angola (Publications)
The 2006-2007 Angola Malaria Indicator Survey (AMIS) is the first nationally representative household survey in the country assessing coverage of the key malaria control interventions and measuring ma