Identification of new PNEPs indicates a substantial non-PEXEL exportome and underpins common features in<em> Plasmodium falciparum</em> protein export (Publications)
Malaria blood stage parasites export a large number of proteins into their host erythrocyte to change it from a container of predominantly hemoglobin optimized for the transport of oxygen into a niche
Modeling the public health impact of malaria vaccines for developers and policymakers (Publications)
BACKGROUND: Efforts to develop malaria vaccines show promise. Mathematical model-based estimates of the potential demand, public health impact, and cost and financing requirements can be used to infor
Geographic distribution, age pattern and sites of lesions in a cohort of Buruli ulcer patients from the mape basin of cameroon (Publications)
Buruli ulcer (BU), a neglected tropical disease of the skin, caused by Mycobacterium ulcerans, occurs most frequently in children in West Africa. Risk factors for BU include proximity to slow flowing
Local concepts of anemia-related illnesses and public health implications in the Taabo health demographic surveillance system, Côte d'Ivoire (Publications)
BACKGROUND: A 14-month prospective longitudinal study conducted in the Taabo health demographic surveillance system (HDSS), south-central Côte d'Ivoire, revealed high prevalence of anemia in different
Fexinidazole: a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness (Publications)
BACKGROUND: Human African trypanosomiasis (HAT), also known as sleeping sickness, is a fatal parasitic disease caused by trypanosomes. Current treatment options for HAT are scarce, toxic, no longer ef
Bovine tuberculosis at a cattle-small ruminant-human interface in Meskan, Gurage region, central Ethiopia (Publications)
ABSTRACT: BACKGROUND: Bovine tuberculosis (BTB) is endemic in Ethiopian cattle. The aim of this study was to assess BTB prevalence at an intensive contact interface in Meskan Woreda (district) in catt
Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second stage human African trypanosomiasis (Publications)
Novel drugs to treat human African trypanosomiasis (HAT) are still urgently needed despite the recent addition of nifurtimox-eflornithine combination therapy (NECT) to WHO Model Lists of Essential Med