Antimicrobial-resistant <em>Escherichia coli</em> strains and their plasmids in people, poultry, and chicken meat in Laos (Publications)
Antimicrobial resistant (AMR) Enterobacterales are widely distributed among the healthy population of the Indochinese peninsula, including Laos. However, the local reservoir of these pathogens are cur
Researching, co-creating and testing innovations in paper-based health information systems (PHISICC) to support health workers’ decision-making:... (Publications)
Background Health information systems are crucial to provide data for decision-making and demand for data is constantly growing. However, the link between data and decisions is not always rational or
CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for <em>Plasmodium falciparum </em>malaria transmission research (Publications)
The malaria parasite Plasmodium falciparum replicates inside erythrocytes in the blood of infected humans. During each replication cycle, a small proportion of parasites commits to sexual development
Prevalence of sero-markers and non-invasive assessment of liver cirrhosis in patients with hepatitis B virus infection in Freetown, Sierra Leone: a... (Publications)
BACKGROUND: Hepatitis B virus (HBV) is a major global health problem. Although sub-Saharan Africa has a high proportion of the global burden of HBV, the epidemiology and clinical features of HBV in th
Reaching absent and refusing individuals during home-based HIV testing through self-testing-at what cost? (Publications)
Introduction: In the HOSENG trial (NCT03598686), the secondary distribution of oral self-tests for persons absent or refusing to test during a home-based HIV testing campaign in rural Lesotho resulted
Socio-cultural factors for breastfeeding cessation and their relationship with child diarrhoea in the rural high-altitude Peruvian Andes - a... (Publications)
BACKGROUND: In some areas of the world, breast milk is seen as a potential source of child diarrhoea. While this belief has been explored in African and Southeast Asian countries, it remains vastly un
Surveillance of molecular markers of <em>Plasmodium falciparum</em> artemisinin resistance (<em>kelch</em>13 mutations) in Papua New Guinea between... (Publications)
Plasmodium falciparum resistance to artemisinin-based combination therapy (ACT) is a global threat to malaria control and elimination efforts. Mutations in the P. falciparum kelch13 gene (Pfk13) that
A high-throughput cell- and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma (Publications)
The detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibodies in the serum of an individual indicates prior infection or vaccination. However, it provides limited i
Common haplotypes at the <em>CFH </em>locus and low-frequency variants in <em>CFHR2 </em>and <em>CFHR5 </em>associate with systemic FHR concentrations... (Publications)
Age-related macular degeneration (AMD) is the principal cause of blindness in the elderly population. A strong effect on AMD risk has been reported for genetic variants at the CFH locus, encompassing