Antiprotozoal activity of Turkish <em>Origanum onites</em> essential oil and its components (Publications)
carvacrol (70.6%), followed by linalool (9.7%), p-cymene (7%), gamma-terpinene (2.1%), and thymol (1.8%). The oil showed significant in vitro activity against T. b. rhodesiense (IC50 180 ng/mL), and moderate
Repurposing of tuberculosis drug candidates for the treatment of <em>Mycobacterium ulcerans</em> disease (Publications)
ulcerans. Historically, the disease was treated by surgical excision of the skin lesions, until an 8-week combination therapy of rifampicin and streptomycin was introduced in 2004. This treatment modality
The burden of surgical site infections and related antibiotic resistance in two geographic regions of Sierra Leone: a prospective study (Publications)
5%). The incidence rate of SSI was 5.5 per 1000 patient-days, and the cumulative incidence of SSI was 8.2%. Common bacteria isolated in MH were Escherichia coli (6,33.3%) and Pseudomonas aeruginosa (3,16
Effects of structurally different HDAC inhibitors against <em>Trypanosoma cruzi</em>, <em>Leishmania</em>, and <em>Schistosoma mansoni</em> (Publications)
parasites, but it was too toxic against host cells, hampering further studies. The retinoic 2'-aminoanilide 8 was less potent than 4 in all parasitic assays, but as its toxicity is considerably lower, it could
Anthelmintic activity and cytotoxic effects of compounds isolated from the fruits of <em>Ozoroa insignis</em> del. (Anacardiaceae) (Publications)
s elegans and identified by NMR spectroscopic analysis and mass spectrometric studies. Isolated 6-[8(Z)-pentadecenyl] anacardic (1), 6-[10(Z)-heptadecenyl] anacardic acid (2), and 3-[7(Z)-pentadecenyl]
Distribution of bovine <em>Fasciola gigantica</em> (Cobbold, 1885) in the district des Savanes, northern Côte d'Ivoire (Publications)
of the district des Savanes. Among the unsuspected livers, five were positive for F. gigantica (9.8%). The distribution of fascioliasis showed considerable spatial heterogeneity, both at regional (ranging
Access to water and sanitation infrastructures for primary schoolchildren in the south-central part of Côte d’Ivoire (Publications)
access to drinking water. The survey was comprised of a questionnaire directed at schoolchildren aged 8–17 years, an assessment of the WASH infrastructure, and the testing of drinking water samples for E
TIDE analysis of <em>Cryptosporidium </em>infections by <em>gp60 </em>typing reveals obscured mixed infections (Publications)
diversity. Retrospective sample analysis was conducted on archived chromatograms. RESULTS: For C. parvum, 8.6% multi-strain infections (13 out of 152) obscured by currently used consensus base calling were detected
<em>In vitro, in vivo</em>, and ADME evaluation of SF5-containing <em>N,N'</em>-diarylureas as antischistosomal agents (Publications)
presence of albumin (> 70% at 10 μM), endowed with decent cytotoxicity profile (SI against L6 cells > 8.5) and good microsomal hepatic stability (> 62.5% of drug remaining after 60 min), were tested in S
Exposure to ozone gases in pulp mills and the onset of rhinitis (Publications)
found to be at increased risk of noninfectious rhinitis [HR 3.4, 95% confidence interval (95% CI) 1.3-8.7] when compared with control workers. Bleachery workers without self-reported ozone gassings were not