Antimycobacterial, antiprotozoal and cytotoxic potential of twenty-one brown algae (Phaeophyceae) from British and Irish waters (Publications)
leishmanicidal activity, with H. siliquosa and B. bifurcata again being the most active (IC50s 6.4 and 8.6 mug/mL). When tested against M. tuberculosis, only the B. bifurcata extract was found to have some
MAGE-C1/CT-7 expression in plasma cell myeloma: sub-cellular localization impacts on clinical outcome (Publications)
MAGE-C1/CT-7, and NY-ESO-1 was investigated on paraffin-embedded bone marrow biopsies from 219 PM and 8 monoclonal gammopathy of undetermined significance (MGUS) patients. The frequency and prognostic impact
Lagunamide C, a cytotoxic cyclodepsipeptide from the marine cyanobacterium <em>Lyngbya majuscula</em> (Publications)
displayed potent cytotoxic activity against a panel of cancer cell lines, such as P388, A549, PC3, HCT8, and SK-OV3 cell lines, with IC(50) values ranging from 2.1nM to 24.4nM. Compound 1 also displayed
3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential (Publications)
has good oral bioavailability (51% at 20 mg/kg) and a reasonable half-life (t(1/2) approximately 7-8 h)
Discordances in the application of different criteria for quantification of paediatric abdominal obesity: an analysis of two Swiss studies (Publications)
obesity varied between 3.1 and 49.4% in boys, and 4.7 and 55.5% in girls (Ballabeina), and between 1.8 and 36.3% in boys and 4.5 and 37.3% in girls (KISS). Among children considered as abdominally obese
Sequence analysis of the MSP 1 gene of <em>Plasmodium falciparum</em> isolates from Hainan, China (Publications)
of the MSP1 from this two Chinese isolates were identical with each other except for Blocks 2, 4 and 8. CONCLUSION: The sequences of the MSP 1 from two Chinese isolates of P. falciparum belong to the MAD20
Antiprotozoal, antimycobacterial and cytotoxic potential of some British green algae (Publications)
only C. rupestris and U. lactuca had moderate trypanocidal activity against T. cruzi (IC(50) values 80.8 and 34.9 mug/ml). Again, all four extracts showed leishmanicidal activity with IC(50) values ranging
Assessing health risk due to exposure to arsenic in drinking water in Hanam province, Vietnam (Publications)
probabilistic approach. The results showed that arsenic concentrations in tube-well water ranged from 8-579 ppb (mean 301 ppb) before filtration and current sand filters used by the households did not meet
Sociocultural determinants of anticipated acceptance of pandemic influenza vaccine in Pune, India: a community survey using mixed-methods (Publications)
sociocultural determinants of vaccine acceptance. RESULTS: Over 93 % anticipated acceptance at no-cost; 87.8 % for INR 150 nasal vaccine; 74.1 % for INR 500 and 61.7 % for INR 1000 injectable vaccines. Some r
Estimating healthcare costs of acute gastroenteritis and human campylobacteriosis in Switzerland (Publications)
Campylobacter spp. for euro12.3 million, patients testing positive for Campylobacter spp. for euro1.8 million and hospitalized campylobacteriosis patients for euro6.5 million/year. Healthcare costs of