Cost-effectiveness of malaria intermittent preventive treatment in infants (IPTi) in Mozambique and the United Republic of Tanzania (Publications)
these figures. FINDINGS: The cost per clinical episode of malaria averted was US$ 1.57 (range: US$ 0.8-4.0) in Ifakara and US$ 4.73 (range: US$ 1.7-30.3) in Manhica; the cost per DALY averted was US$ 3.7
Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation (Publications)
STOCSY, and 19F-edited 1H-1H STOCSY (X-STOCSY) spectroscopic maps, with a resolution of approximately 0.8 Hz/pt for both nuclei. The efficient statistical editing provided by these methods readily allowed the
New loci associated with kidney function and chronic kidney disease (Publications)
807 individuals with CKD (cases)). Follow-up of the 23 new genome-wide-significant loci (P < 5 x 10(-8)) in 22,982 replication samples identified 13 new loci affecting renal function and CKD (in or near
<em>In vitro</em> and <em>in vivo</em> efficacy of mefloquine-based treatment against alveolar echinococcosis (Publications)
with 12 muM was not. Oral application of mefloquine (25mg/kg body weight, twice a week for a period of 8 weeks) in E. multilocularis-infected mice was ineffective in achieving any reduction of parasite weight
Human resources for health care delivery in Tanzania: a multifaceted problem (Publications)
given for this. Amongst the clinical staff, 38% were absent because of attendance of seminar sessions, 8% because of long-training, 25% were on official travel and 20% were on leave. RCH clinic nurses were
Use of B-type natriuretic peptide in the management of acute dyspnea in patients with pulmonary disease (Publications)
in the BNP group as compared with $5671 in the clinical group (P = .008). Inhospital mortality was 8% in both groups. CONCLUSIONS: CHF is a major cause of acute dyspnea in patients with a history of pulmonary
Pacing pattern and speed skating performance in competitive long-distance events (Publications)
in each instance for women's 3,000 m (p < 0.001). For the 5,000 m races, laps 5-12 in women and laps 8-12 in men were slower compared with previous laps (p < 0.001, for both sexes). For men's 10,000 m, skaters
The antiprotozoal activity of methylated flavonoids from <em>Ageratum conyzoides</em> L (Publications)
donovani (Kala-Azar, IC(50)=3.4 microg/mL) as well as Plasmodium falciparum (Malaria tropica, IC(50)=8.0 microg/mL). In the current study, we sought for potentially active constituents of Ageratum conyzoides
Efficacy of the cyclooctadepsipeptide PF1022A against <em>Heligmosomoides bakeri in vitro</em> and <em>in vivo</em> (Publications)
levamisole and ivermectin in vivo. For example, at 0.125 mg/kg PF1022A a worm burden reduction of 91.8% was observed. The use of drug combinations did not further enhance the in vitro and in vivo activity
Molecular epidemiology of <em>Plasmodium falciparum</em> infections among asymptomatic inhabitans of a holoendemic malarious area in northern Ghana (Publications)
length polymorphism typing of the P. falciparum msp2 revealed a mean msp2 multiplicity of 3.4 (range: 1-8) genotypes per PCR positive sample. Multiplicity increased with age until 5-9 years and then started
