Dental care behaviour in Switzerland (Publications)
groups. Treatment needs including caries/filling/endodontic treatment (10%), crowns/FDP/RDP/implants (8%), toothache (5%), extraction (5%), periodontal complaints (2%), or orthodontic appliances (2%) were
Influence of parasite density and sample storage time on the reliability of <em>Entamoeba histolytica</em>-specific PCR from formalin-fixed and... (Publications)
density, and reliability of PCR was analyzed. E. histolytica PCR was positive in 20 of 34 biopsies (58.8%); 2 of these 20 were microscopically negative for amebae in neighboring tissue sections. PCR was negative
The molecular clock of <em>Mycobacterium tuberculosis</em> (Publications)
clock of MTB. For data sets where such calibration was possible, we obtained a clock rate between 1x10-8 and 5x10-7 nucleotide changes per-site-per-year (0.04-2.2 SNPs per-genome-per-year), with substantial
Non-randomized studies using causal-modelling may give different answers than RCTs: a meta-epidemiological study (Publications)
RCTs (120669 patients). MSM-studies indicated effect estimates in the opposite direction from RCTs for 8 clinical questions (42%), and their 95% CI did not include the RCT estimate in 9 clinical questions
Synthesis, <em>in-vitro</em> antiprotozoal activity and molecular docking study of isothiocyanate derivatives (Publications)
Leishmania donovani with IC50 values between 0.4 and 1.0microM and selectivity index (SI) ranged from 7.8 to 18.4, comparable to the standard drug miltefosine (IC50=0.7muM). Compound 7h demonstrated the best
Association of adult lung function with accelerated biological aging (Publications)
1-PAI1) and their related age-adjusted measures were estimated from peripheral blood at two time points (8-to-11 years apart) in adults from two cohorts: SAPALDIA (n=987) and ECRHS (n=509). Within each cohort
<em>Vivax </em>malaria in pregnancy and lactation: a long way to health equity (Publications)
with maternal anaemia and increased adverse perinatal outcomes. Providing radical cure for women with 8-aminoquinolines (e.g., primaquine) is hindered by gender-specific complexities. CASE PRESENTATION: A
Epitope mapping and fine specificity of human T and B cell responses for novel candidate blood-stage malaria vaccine P27A (Publications)
major differences between adjuvants or populations. Affinity of anti-P27A antibodies was around 10−8 M in all groups. Pre-exposed volunteers presented anti-P27A with higher affinity than unexposed volunteers
Colloidal transformations in MS2 virus particles: driven by pH, influenced by natural organic matter (Publications)
spherical with core-shell-type structure with a total diameter of 27 nm and a core radius of around 8 nm. Reversible transformations from 27 nm particles at pH = 7.0 to micrometer-sized aggregates at pH
Disability progression among leprosy patients released from treatment: a survival analysis (Publications)
complaints of any kind during treatment were identified as risk factors with Hazard Ratios of 1.6 and 1.8 respectively. CONCLUSIONS: People released from treatment as cured of leprosy are susceptible to worsening
