Quality of life is associated with physical activity and fitness in cystic fibrosis (Publications)
cross-sectionally (r = 0.30-0.46). Muscle power (r = 0.25-0.32) and peak aerobic power (r = 0.24-0.35) were positively related to 4 scales each, and reported physical activity to 1 scale (r = 0.29). Changes in [...] significantly related to changes in reported activity (r = 0.35-0.39), peak aerobic power (r = 0.31-0.34), and peak oxygen uptake (r = 0.26-0.37) in 3 scales each. Established associates of HRQoL such [...] such as FEV1 or body mass index correlated positively with fewer scales (all ...
Exposure to surrounding greenness and natural-cause and cause-specific mortality in the ELAPSE pooled cohort (Publications)
mortality (Hazard Ratio (HR) 0.95 (95% CI: 0.94, 0.96)). The associations attenuated after adjustment for air pollution [HR (95% CI): 0.97 (0.96, 0.98) adjusted for PM2.5; 0.98 (0.96, 0.99) adjusted for NO2] [...] follow-up. The mean NDVI in the pooled cohort was 0.33 (SD 0.1) and 0.34 (SD 0.1) in the 300-m grid and 1-km buffer. In the main fully adjusted model, 0.1 unit increment of NDVI inside 300-m grid was associated
Limited sampling models to predict the pharmacokinetics of nevirapine, stavudine, and lamivudine in HIV-infected children treated with pediatric... (Publications)
stavudine AUC (mpe%: -0.6%, 95% confidence interval: -2.2 to +1.0; rmse%: 6.5%; r: 0.98) and lamivudine AUC (mpe%: -0.3%, 95% confidence interval: -1.7 to +1.1; rmse%: 5.6%; r: 0.99) was found; this model [...] model was also highly accurate and precise for nevirapine AUC (mpe%: -0.2%, 95% confidence interval: -1.0 to +0.7; rmse%: 3.4%; r: 0.99). A limited sampling model using three time points (1, 2, 6 hours) [...] lamivudine, although the 6-hour sample was acceptable for nevirapine (mpe%: -0.8...
Risk factors associated with urogenital schistosomiasis: a multilevel assessment approach using an Oversampling Schistosomiasis Survey (SOS)... (Publications)
(aOR=2.4; 95% CI: 1.0 to 5.2) and residing in Ogou (aOR=28.6) increased intensity, whereas living in Est-Mono (aOR=0.0; 95% CI: 0.0 to 0.08) or using rainwater (aOR=0.0; 95% CI: 0.0 to 0.4) decreased it. [...] uncovering a 15.0% prevalence of urogenital schistosomiasis (95% CI: 14.1% to 15.8%). Notably, 48.3% (95% CI: 45.1% to 51.5%) showed heavy-intensity infections, averaging 38 eggs per 10 mL (range: 0-9688). Key [...] 6) and residing in the Ogou district (aOR=11.2), while the Est-Mono...
Exposure to surrounding greenness and natural-cause and cause-specific mortality in the ELAPSE pooled cohort (Publications)
mortality (Hazard Ratio (HR) 0.95 (95% CI: 0.94, 0.96)). The associations attenuated after adjustment for air pollution [HR (95% CI): 0.97 (0.96, 0.98) adjusted for PM2.5; 0.98 (0.96, 0.99) adjusted for NO2] [...] follow-up. The mean NDVI in the pooled cohort was 0.33 (SD 0.1) and 0.34 (SD 0.1) in the 300-m grid and 1-km buffer. In the main fully adjusted model, 0.1 unit increment of NDVI inside 300-m grid was associated
Limited sampling models to predict the pharmacokinetics of nevirapine, stavudine, and lamivudine in HIV-infected children treated with pediatric... (Publications)
stavudine AUC (mpe%: -0.6%, 95% confidence interval: -2.2 to +1.0; rmse%: 6.5%; r: 0.98) and lamivudine AUC (mpe%: -0.3%, 95% confidence interval: -1.7 to +1.1; rmse%: 5.6%; r: 0.99) was found; this model [...] model was also highly accurate and precise for nevirapine AUC (mpe%: -0.2%, 95% confidence interval: -1.0 to +0.7; rmse%: 3.4%; r: 0.99). A limited sampling model using three time points (1, 2, 6 hours) [...] lamivudine, although the 6-hour sample was acceptable for nevirapine (mpe%: -0.8...
Sedentary behavior in children by wearable cameras: development of an annotation protocol (Publications)
(mean kappa=0.85, 95% CI=0.83, 0.87). Inter-rater reliability for screen-based sedentary behavior (mean kappa=0.72, 95% CI=0.62, 0.82) and nonscreen sedentary behavior (kappa=0.69, 95% CI=0.65, 0.72) showed [...] showed substantial agreement. Inter-rater reliability for location (kappa=0.91, 95% CI=0.88, 0.93) showed almost perfect agreement. CONCLUSIONS: A reliable annotation protocol to categorize wearable camera
Prediction of long-term disability in multiple sclerosis (Publications)
EP-latencies(T0) (rho = 0.68, p < 0.0001), but not with MR-parameters(T0). EDSS(T4) as predicted by the formula EDSS(T4) = 4.194 + 0.088 * z-score P100(T0) + 0.071 * z-score CMCT(UE, T0) correlated with [...] with the observed values (rho = 0.69, p < 0.0001). Conclusion: Combined EPs allow prediction of long-term disability in small groups of patients with MS. This may have implications for the choice of monitoring [...] prospectively investigated with VEPs, MEPs and the Expanded Disability...
Rhinitis in Swiss adults is associated with asthma and early life factors, but not second hand tobacco smoke or obesity (Publications)
11, 1.79). Older subjects were at lower risk (0.96; 0.95,0.97 per year), as were those raised on a farm (0.64; 0.49,0.84), with older siblings (0.92; 0.86,0.97 per sib) or from rural areas. The risk of [...] also increased in subjects with physician diagnosed asthma (4.02; 2.86, 5.67), reduced in males (0.59; 0.46, 0.77), but not associated with upbringing on a farm or older siblings. There were no significant
Sedentary behavior in children by wearable cameras: development of an annotation protocol (Publications)
(mean kappa=0.85, 95% CI=0.83, 0.87). Inter-rater reliability for screen-based sedentary behavior (mean kappa=0.72, 95% CI=0.62, 0.82) and nonscreen sedentary behavior (kappa=0.69, 95% CI=0.65, 0.72) showed [...] showed substantial agreement. Inter-rater reliability for location (kappa=0.91, 95% CI=0.88, 0.93) showed almost perfect agreement. CONCLUSIONS: A reliable annotation protocol to categorize wearable camera
