Prognostic value of quickSOFA as a predictor of 28-day mortality among febrile adult patients presenting to emergency departments in Dar es Salaam,... (Publications)
prognostic accuracy of qSOFA (AUROC 0.80, 95% CI 0.73-0.87) for 28-day mortality was similar to SOFA (AUROC 0.79, 0.71-0.87; p = 0.1) and better than SIRS (AUROC 0.61, 0.52-0.71; p
Variability of the human serum metabolome over 3 months in the EXPOsOMICS Personal Exposure Monitoring study (Publications)
across all metabolic features was 0.51 (IQR: 0.29) and 0.64 (IQR: 0.25) for the 184 uniquely identified compounds. For this group, the median ICC marginally changed (0.63) when we included common confounders [...] ICC was largest among glycerophospholipids (median ICC 0.70) and steroids (0.67), and lowest for amino acids (0.61) and the O-acylcarnitine class (0.44). ICCs varied substantially within chemical classes [...] Our results suggest that the metabolome as measured with untargeted LC-HRMS...
Prevalence and risk factors of <em>Strongyloides stercoralis</em> in Takeo Province, Cambodia (Publications)
CI: 1.4 - 2.0; P < 0.001). Participants who had a latrine at home were significantly less frequently infected with S. stercoralis than those who did not (OR: 0.7; 95% CI: 0.4 - 0.8; P = 0.003). Muscle [...] Muscle pain (OR: 1.3; 95% CI: 1.0 - 1.6; P = 0.028) and urticaria (OR: 1.4; 95% CI: 1.1 - 1.8; P = 0.001) were significantly associated with S. stercoralis infection. CONCLUSIONS: S. stercoralis is highly prevalent [...] RESULTS: Eight intestinal helminth species were diagnosed. Hookworm...
Effects of a lifestyle intervention on adiposity and fitness in overweight or low fit preschoolers (Ballabeina) (Publications)
interaction = 0.001) and low fit children (n = 154) more beneficial effects on all adiposity outcomes (p for interaction /=0.2). Average intervention effect sizes for BMI were -0.12, -0.05, -0.26 and -0.02 kg/m2 [...] kg/m2 and for aerobic fitness were 0.40, 0.30, 0.12 and 0.36 stages for OW, normal weight, low fit and normal fit children, respectively. Conclusions: This multidimensional intervention was equally and for
Prognostic value of quickSOFA as a predictor of 28-day mortality among febrile adult patients presenting to emergency departments in Dar es Salaam,... (Publications)
prognostic accuracy of qSOFA (AUROC 0.80, 95% CI 0.73-0.87) for 28-day mortality was similar to SOFA (AUROC 0.79, 0.71-0.87; p = 0.1) and better than SIRS (AUROC 0.61, 0.52-0.71; p
A meta-analysis on residential exposure to magnetic fields and the risk of amyotrophic lateral sclerosis (Publications)
pooled relative risk (RR) of 0.71 [95% confidence interval (CI): 0.48, 1.07] for the most exposed population group (either 0.1 muT) was found. Little heterogeneity (I2=0.00%, p=0.67) and indication for publication [...] publication bias (PBegg's test=0.22; PEgger's test=0.19) was seen. Overall, we found no evidence for an association between residential exposure to ELF-MF and the risk of ALS, although the number of exposed
A meta-analysis on residential exposure to magnetic fields and the risk of amyotrophic lateral sclerosis (Publications)
pooled relative risk (RR) of 0.71 [95% confidence interval (CI): 0.48, 1.07] for the most exposed population group (either 0.1 muT) was found. Little heterogeneity (I2=0.00%, p=0.67) and indication for publication [...] publication bias (PBegg's test=0.22; PEgger's test=0.19) was seen. Overall, we found no evidence for an association between residential exposure to ELF-MF and the risk of ALS, although the number of exposed
Early life risk factors of motor, cognitive and language development: a pooled analysis of studies from low/middle-income countries (Publications)
schooling had 0.14 SD (95% CI 0.05 to 0.25) higher cognitive scores compared with children whose mothers had primary education. Preterm birth was associated with 0.14 SD (-0.24 to -0.05) and 0.23 SD (-0.42 to [...] cognitive and motor development with effects ranging from -0.18 to -0.10 SDs. CONCLUSIONS: Differential parental, environmental and nutritional factors contribute to disparities in child development across [...] to -0.03) reductions in cognitive and motor scores, respectively....
Low-grade inflammation and estimates of insulin resistance during the menstrual cycle in lean and overweight women (Publications)
P = 0.004). Central accumulation of body fat correlated to the mean hs-CRP concentration (r = 0.63, P = 0.007) and the mean homeostasis model assessment index for insulin resistance (r = 0.75, P = 0.001) [...] (5%, P < 0.05). During the menstrual cycle, using repeated measurements, hs-CRP correlated inversely to estradiol (beta-coefficient, -0.23, P < 0.0001) and SHBG concentrations (beta-coefficient, -0.83, P [...] were highest in the early follicular phase (P < 0.00001). SHBG concentrations...
Relationship of aerobic fitness and motor skills with memory and attention in preschoolers (Ballabeina): a cross-sectional and longitudinal study (Publications)
attention (r = 0.16, p = 0.03). A shorter time in the agility test was independently associated with a better performance both in working memory (r = -0.17, p = 0.01) and in attention (r = -0.20, p = 0.01). In [...] related to improvements in attention (r = 0.16, p = 0.03), while baseline dynamic balance was associated with improvements in working memory (r = 0.15, p = 0.04). CONCLUSIONS: In young children, higher [...] in preschool children. METHODS: Data from 245 ethnically diverse preschool...
