Effect of amoxicillin-clavulanate in clinically diagnosed acute rhinosinusitis: a placebo-controlled, double-blind, randomized trial in general... (Publications)
amoxicillin-clavulanate and placebo was -0.29 (95% CI, -0.93 to 0.34) in the number of days with restrictions due to rhinosinusitis and -0.60 (95% CI, -1.41 to 0.21) in patients with a positive rhinoscopy [...] hazard ratio for the effect of amoxicillin-clavulanate was 0.99 (95% confidence interval [CI], 0.68-1.45) on time to cure and 1.28 (95% CI, 0.80-2.05) in the prespecified subgroup of patients with a positive
Carotid intima-media thickness in the Spanish population: reference ranges and association with cardiovascular risk factors (Publications)
did women (0.71 vs 0.67 mm). The strongest predictors of this measure were age (coefficients for 10-year increase: 0.65 and 0.58 for women and men, respectively), smoking in men (coefficient: 0.26), high-density [...] cholesterol in women (coefficient for 10 mg/dL, increase: -0.08) and pulse pressure in both sexes (coefficients for 10 mmHg increase: 0.08 and 0.23 for women and men, respectively). The results were similar
Consistently high estimates for the proportion of human exposure to malaria vector populations occurring indoors in rural Africa (Publications)
($${\pi }_{\hbox{ i }}^{\hbox{ B }}$$ = 0.79-1.00). Neither An. gambiae s.l. nor An. funestus s.l. strongly preferred feeding indoors (P(i) = 0.40-0.63 and 0.22-0.69, respectively), but they overwhelmingly [...] ngly preferred feeding at times when most humans were indoors (P(fl) = 0.78-1.00 and 0.86-1.00, respectively). CONCLUSIONS: These quantitative summaries of behavioural interactions between humans and [...] behaviour from six rural sites in Burkina Faso, Tanzania, Zambia, and Kenya, with...
A pilot study characterizing real time exposures to particulate matter and carbon monoxide from cookstove related woodsmoke in rural Peru (Publications)
(r = 0.67 p = 0.024 n = 11) and dinner (r = 0.72 p = 0.0011 n = 17) in all study households. Personal PM2.5 exposures and kitchen CO concentrations were also correlated during lunch (r = 0.76 p = 0.018 [...] 018 n = 9) and dinner (r = 0.60 p = 0.018 n = 15). CO may be a useful indicator of PM during 4-h time scales measured in real time, particularly during high woodsmoke exposures, particularly during residential
Baby-friendly hospital designation has a sustained impact on continued breastfeeding (Publications)
in current BFHs (cessation hazard ratio 0.60, 95% confidence interval [0.42, 0.84]) or in former BFHs (cessation hazard ratio 0.68, 95% confidence interval [0.48, 0.97]). Overall, the results support continued [...] were used for exclusive (0-6 months) and continued (6-12 months) breastfeeding duration. Average duration of exclusive breastfeeding (13.1 weeks, 95% confidence interval [12.0, 17.4]) and any breastfeeding
The epidemiology of chronic kidney disease and the association with non-communicable and communicable disorders in a population of sub-Saharan Africa (Publications)
CI 0-4%) as high, and 9 (1%) (95% CI 0-3%) as very high risk according to KDIGO. History of tuberculosis (OR 3.75, 95% CI 1.66-8.18; p = 0.001) and schistosomiasis (OR 2.49, 95% CI 1.13-5.18; p = 0.02) [...] increasing systolic blood pressure (OR 1.02 per 1 mmHg, 95% CI 1.00-1.03; p = 0.01). Increasing BMI (OR 0.92 per 1kg/m2, 95% CI 0.88-0.96; p = /=3 in 10% of all CKD cases. We observed a high prevalence estimate
Nutritional adequacy in rural Limpopo Province, South Africa: maternal and child dietary diversity in the context of perinatal HIV exposure (Publications)
DD score ( 0.05). At 7 months, compared with HUU children (n=234), HEU children (n=71) had a lower median HAZ of −0.54 (interquartile range (IQR) −1.21 - 0.11) v. median −0.1, IQR −0.76 - 0.99 (p [...] 2.26 (1.63) v. HUU 2.32 (1.63); p=0.08). At 17 months, the mean DD was 3.38 (1.62) and remained similar between HUU and HEU children (3.41 (1.57) v. 3.29 (1.82); p=0.333). No significant association was
Adopting clean fuels and technologies on school buses. Pollution and health impacts in children (Publications)
greater changes in FVC and FEV1 (0.02 [95% CI, 0.003 to 0.05] and 0.01 [95% CI, -0.006 to 0.03] L/yr, respectively), and lower absenteeism (-8% [95% CI, -16.0 to -0.7%]), with stronger associations among
Prevalence of malaria across Papua New Guinea after initial roll-out of insecticide-treated mosquito nets (Publications)
with P. vivax (3.8%; 95% CI 2.4, 5.7) or P. malariae (0.3%; 95% CI 0.1, 0.6). Parasitaemia was strongly age-dependent with a P. falciparum peak at age 5-9 years and a P. vivax peak at age 1-4 years, yet with [...] and high community coverage were associated with reduced odds of infection (OR = 0.64 and 0.07, respectively; both P < 0.001). Splenomegaly in children and anaemia were common morbidities attributable to [...] Malaria prevalence ranged from 0% to 49.7% with a weighted average of 12.1%...
Virosome-formulated <em>Plasmodium falciparum</em> AMA-1 & CSP derived peptides as malaria vaccine: randomized phase 1b trial in semi-immune... (Publications)
control children between study days 30 and 365 (0.0035 episodes per day at risk for PEV3B vs. 0.0069 for Inflexal(R)V; RR = 0.50 [95%-CI: 0.29-0.88], p = 0.02). CONCLUSION: These findings provide a strong [...] a malaria endemic area were immunized with PEV3B or virosomal influenza vaccine Inflexal(R)V on day 0 and 90. RESULTS: No serious or severe adverse events (AEs) related to the vaccines were observed. The [...] injection site, which affected more children in the Inflexal(R)V group compared...
