Ro 15-0216: a nitroimidazole compound active in vitro against human and animal pathogenetic African trypanosomes (Publications)
value) was established: 0.0957 microgram ml-1 (T. b. brucei TC221), 0.1327 microgram ml-1 (T. b. gambiense STIB 754-A), 0.0450 microgram ml-1 (T. b. rhodesiense STIB 704-BABA), 0.0896 microgram ml-1 (T [...] (T. congolense ILNat 3.1) and 0.0109 microgram ml-1 (T. vivax ILRAD 1392). The IC50 value of its major metabolite Ro 19-9638 was 0.0341 microgram ml-1 (T. b. rhodesiense STIB 704-BABA). Furthermore, minimum
Ro 15-0216: a nitroimidazole compound active in vitro against human and animal pathogenetic African trypanosomes (Publications)
value) was established: 0.0957 microgram ml-1 (T. b. brucei TC221), 0.1327 microgram ml-1 (T. b. gambiense STIB 754-A), 0.0450 microgram ml-1 (T. b. rhodesiense STIB 704-BABA), 0.0896 microgram ml-1 (T [...] (T. congolense ILNat 3.1) and 0.0109 microgram ml-1 (T. vivax ILRAD 1392). The IC50 value of its major metabolite Ro 19-9638 was 0.0341 microgram ml-1 (T. b. rhodesiense STIB 704-BABA). Furthermore, minimum
Brief research report: quantitative analysis of potential coronary microvascular disease in suspected long-COVID syndrome (Publications)
significantly lower [31.8 +/- 5.1 vs. 37.8 +/- 6.0 (mul/g/beat), P < 0.001] and the T2 relaxation time was significantly higher (46.2 +/- 3.6 vs. 42.7 +/- 2.8 ms, P = 0.002) post-COVID-19 compared to healthy controls [...] and T1 and T2 relaxation times were not correlated to the COVID-19 severity (Spearman r = -0.302, -0.070, and -0.297, respectively) or the presence of symptoms. The stress MBF showed a U-shaped relation [...] correlation to T1 relaxation time, and a negative correlation to T2...
The effect of immunization schedule with the malaria vaccine candidate RTS,S/AS01E on protective efficacy and anti-circumsporozoite protein antibody... (Publications)
injection was associated with a 54% risk reduction of getting malaria (hazard ratio: 0.46; 95% confidence interval (CI): 0.22-0.99) in those participants with a change in avidity above the median. The change [...] third injection was associated with a 77% risk reduction of getting malaria (hazard ratio: 0.23, 95% CI: 0.11-0.51). CONCLUSIONS: Change in IgG response between vaccine doses merits further evaluation as [...] METHODS: Quantity and avidity of anti-CSP IgG in African infants who...
Estimated hourly personal exposures to ambient and nonambient particulate matter among sensitive populations in Seattle, Washington (Publications)
mean = 0.66+/-0.21) for each subject. The mean alpha was significantly lower for subjects monitored during the heating season (0.55+/-0.16) than for those monitored during the nonheating season (0.80+/-0 [...] 80+/-0.17). Our modeled alpha estimates agreed well with those estimated with the sulfur-tracer method (slope = 1.08; R2 = 0.67). We modeled exposure to ambient and nonambient PM with both continuous light [...] median hourly longitudinal correlation between central site concentrations and...
Measuring in-cabin school bus tailpipe and crankcase PM2.5: a new dual tracer method (Publications)
(averages of 0.028 and 0.099 g/km for the two buses) were lower than those from the tailpipe (0.18 and 0.14 g/km), in-cabin PMck concentrations averaging 6.8 microg/m3 were higher than DPMtp (0.91 microg/m3 [...] in-cabin sampling times, very high sensitivities were achieved, with detection limits of 0.002 microg/m3 for DPMtp and 0.05 microg/m3 for PMck [...] significantly higher with bus windows closed (1.4 and 12 microg/m3, respectively) as compared with open (0.44 and 1.3 microg/m3,...
Estimation of percentage body fat in 6- to 13-year-old children by skinfold thickness, body mass index and waist circumference (Publications)
_{adj};{2} 0.78; RMSE 2.85), BMI (R _{adj};{2} 0.62; RMSE 3.73), waist circumference (R _{adj};{2} 0.58; RMSE 3.89), and BMI combined with waist circumference (R _{adj};{2} 0.63; RMSE 3.66) (P < 0.001 for [...] each model. LogSF4 (R _{adj};{2} 0.85; RMSE 2.35) and logSF2 (R _{adj};{2} 0.82; RMSE 2.54) were similarly accurate at predicting PBF and superior to logTSF (R _{adj};{2} 0.75; RMSE 3.02), logTSF combined
Pacing and sprint performance in speed skating during a competitive season (Publications)
less in competition-to-competition sector and total race times (women: 0.02 to 0.33 vs 0.02 to 0.51; men: 0.01 to 0.15 vs 0.02 to 0.57). CONCLUSION: This study confirmed that skaters adopted a fast start
Low-potassium and glucose-free dialysis maintains urea but enhances potassium removal (Publications)
mmol, 80.2 and 63.3 mmol (P < 0.001) were removed by 1K and 2K baths respectively. M(U) was not influenced by M(K) (r = 0.22) and amounted to 491.1 (0K), 508.6 (1K), and 506.2 (2K) mmol (NS) respectively. [...] ml/min, Qd = 500 ml/min, dialysate without glucose, bicarbonate 40 mmol/l), using dialysates containing 0 (0K), 1 (1K), and 2 (2K) mmol/l of K. Mass removal of K (M(K)) and u (M(U)) were measured during the [...] Kt/V were determined. RESULTS: 0K, 1K and 2K treatments were perfectly...
Infectious diseases are associated with carotid intima media thickness in adolescence (Publications)
/=3 infectious diseases vs. none (0.046 mm, 95%CI 0.024; 0.068). In girls, the effect was of same direction but statistically non-significant (0.011 mm, 95%CI -0.015; 0.036). CONCLUSION: The SAPALDIA Youth [...] and 15% girls reported > /=3 infectious diseases (p = 0.136). Two-thirds were vaccinated according to recommendations (boys 56%, girls 61.5%, p = 0.567). Sex-stratified analyses yielded significantly increased
