Combined visual and motor evoked potentials predict multiple sclerosis disability after 20 years (Publications)
of the sum of z-transformed EP latencies (s-EPT0) and other baseline variables with EDSST5. RESULTS: We found that s-EPT0 correlated with EDSST5 (rho=0.72, p [...] (EDSS) scores, combined visual and motor EPs at entry (T0), 6 (T1), 12 (T2) and 24 (T3) months, and a cranial magnetic resonance imaging (MRI) scan at T0 and T2. EDSS testing was repeated at year 14 (T4) and
Case definitions of clinical malaria under different transmission conditions in Kilifi District, Kenya (Publications)
episodes in those from an area of higher transmission (0.84 vs. 0.55 episodes/person/year; incidence rate ratio, 0.66 [95% confidence interval, 0.61-0.72]; P
New 4-aminobicyclo[2.2.2]octane derivatives and their activities against <em>Plasmodium falciparum</em> and <em>Trypanosoma b. rhodesiense</em> (Publications)
potency (IC(50)=0.84-0.99microM, chloroquine: IC(50)=0.12microM). One of the bicyclo[2.2.2]octan-2-yl 4-tert-butylbenzenesulfonates showed the highest antitrypanosomal activity (IC(50)=0.68microM) of the [...] 4-amino-6,7-diarylbicyclo[2.2.2]octane derivatives, but is distinctly less active than suramin (IC(50)=0.0075microM)
Adhärenz-Raten bei Interventionsprogrammen zur Bewegungsförderung älterer Menschen: ein systematischer Literaturüberblick (Publications)
association between adherence rate and training frequency (-2,9%; p=0,042), training duration (-0,2%; p=0,016) and number of participants (-0,1%; p=0,008). CONCLUSION: To ensure a high adherence to training programs
City-dwellers and country folks: lack of population differentiation along an urban-rural gradient in the mosquito <em>Culex pipiens</em> (Diptera:... (Publications)
at 10 microsatellite markers. There was no significant differentiation (FST = 0.016, P = 0.9) or isolation by distance (P = 0.06) among Cx. pipiens populations along an urban-rural gradient. The only significant [...] were between Cx. pipiens and a laboratory population of Cx. pipiens f. molestus (pairwise FST = 0.114-0.148, P
Screening strategy for Chagas disease in a non-endemic country (Switzerland): a prospective evaluation (Publications)
disease was 2.3% among migrants (15.5% in the community testing) and 0% among travellers. The prevalence was 18.0%, 0.8%, 0.5% and 0% among Bolivians, Ecuadorians, Brazilians and other countries respectively
A novel multiple-instance learning-based approach to computer-aided detection of tuberculosis on chest x-rays (Publications)
retraining, our MILbased system significantly outperformed the supervised one (0:86 vs. 0:79 and 0:91 vs. 0:85, p < 0:0001 and p = 0:0002, respectively) [...] annotations were available, the supervised system was not much better than our MILbased method (0:88 vs. 0:86). Thus, the proposed approach achieved highly competitive results without resorting to lesionlevel
Allomonal effect of breath contributes to differential attractiveness of humans to the African malaria vector Anopheles gambiae (Publications)
TE collected more mosquitoes than the control (P = 0.005 and P < 0.001, respectively), as did his BO and the control versus his BR (P < 0.001 and P = 0.034, respectively). The TE of P1 attracted more mosquitoes [...] designated P8 (P < 0.021), whereas the BR of P8 attracted more mosquitoes than the BR of P1 (P = 0.001). The attractiveness of the BO of P1 versus the BO of P8 did not differ (P = 0.346). The BO from either [...] either individual was consistently more attractive than the TE from...
Seroprevalence of Brucellosis and Q-fever in southeast Ethiopian pastoral livestock (Publications)
burnetii using ELISA. The seroprevalences of Brucella was 1.4% (95% confidence interval (CI), 0.8-2.6), 0.9% (95% CI, 0.3-2.7)b and 9.6% (95% CI, 5.2-17.1) in cattle, camels and goats, respectively. Goats and [...] and (OR=1.7 95% CI, 0.9-2.9), respectively. Out of 98 RBPT negative camel sera, 12.0% were positive for ELISA. The seroprevalences of C. burnetii were 31.6% (95% CI, 24.7-39.5), 90.0% (95% CI, 81.8-94.7) [...] species. Being camel and older animal was a risk factor for infection...
Prevalence and clinical relevance of helminth co-infections among tuberculosis patients in urban Tanzania (Publications)
p = 0.040). Moreover, S. mansoni infection was associated with lower sputum bacterial load (aOR 2.63, 95% CI: 1.38-5.26, p = 0.004) and tended to have fewer lung cavitations (aOR 0.41, 95% CI: 0.12-1 [...] hookworm (9.0%, 87) and Schistosoma mansoni (5.7%, 55). An infection with any helminth was not associated with TB (adjusted odds ratio (aOR) 1.26, 95% confidence interval (CI): 0.88-1.80, p = 0.22), but S [...] 12-1.16, p = 0.088). CONCLUSIONS/SIGNIFICANCE: S. mansoni infection was an...