Babanezhad Harikandei K, Salehi P, Ebrahimi S.N, Bararjanian M, Kaiser M, Al-Harrasi A. Synthesis, in-vitro antiprotozoal activity and molecular docking study of isothiocyanate derivatives. Bioorg Med Chem. 2020;28(1):115185. DOI: 10.1016/j.bmc.2019.115185

Brancucci N.M.B, Heussler V.T, Gruring C. Targeting Plasmodium plasmepsin V: hitting two birds with one stone. Trends Parasitol. 2020;36(2):85-87. DOI: 10.1016/j.pt.2019.12.006

Curchod L et al. Temporal variation of pesticide mixtures in rivers of three agricultural watersheds during a major drought in the Western Cape, South Africa. Water Res X. 2020;6:100039. DOI: 10.1016/j.wroa.2019.100039

Farnham A, Utzinger J, Kulinkina A.V, Winkler M.S. Using district health information to monitor sustainable development. Bull World Health Organ. 2020;98:69-71. DOI: 10.2471/BLT.19.239970

Felger I, Snounou G, Hastings I, Moehrle J.J, Beck H.P. PCR correction strategies for malaria drug trials: updates and clarifications. Lancet Infect Dis. 2020;20(1):e20-e25. DOI: 10.1016/S1473-3099(19)30426-8

Fuhrimann S et al. Variability and predictors of weekly pesticide exposure in applicators from organic, sustainable and conventional smallholder farms in Costa Rica. Occup Environ Med. 2020;77:40-47. DOI: 10.1136/oemed-2019-105884

Jacobi J et al. Utilization of research knowledge in sustainable development pathways: Insights from a transdisciplinary research-for-development programme. Environ Sci Policy. 2020;103:21-29. DOI: 10.1016/j.envsci.2019.10.003

Müller-Schulte E, Tuo M.N, Akoua-Koffi C, Schaumburg F, Becker S.L. High prevalence of ESBL-producing Klebsiella pneumoniae in clinical samples from central Cote d'Ivoire. Int J Infect Dis. 2020;91:207-209. DOI: 10.1016/j.ijid.2019.11.024

Nhung N.T.T et al. Exposure to air pollution and risk of hospitalization for cardiovascular diseases amongst Vietnamese adults: case-crossover study. Sci Total Environ. 2020;703:134637. DOI: 10.1016/j.scitotenv.2019.134637

Pelikan K, Jeffrey R, Roelcke T. The time where the British took the lead is over” - ethical aspects of writing in complex research partnerships. Res Ethics. 2020(in press)

Our research

The bacterial meningitis project involves longitudinal studies of the molecular epidemiology of comparatively carriage and disease of N. meningititdis and S. pneumoniae. The studies are being carried out in Northern Ghana and Burkina Faso and aim to enhance the understanding of the dynamics of meningitis epidemics in the African Meningitis Belt. The results provide important background information for the evaluation and introduction of new conjugate vaccines against meningococcal and pneumococcal infections in Africa.

 

Meningococcal Meningitis: Clonal Waves of Colonisation and Disease in the Meningitis Belt of Sub-Saharan Africa

Bacterial meningitis is a medical emergency and remains one of the major health problems in Sub-Saharan Africa. The three most important agents are Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae. All three pathogens are common colonizers of the human nasopharynx, invasive disease is usually a rare event.

Meningitis