Brown J.A, Amstutz A, Nsakala B.L, Seeburg U, Vanobberghen F, Muhairwe J, Klimkait T, Daniel Labhardt N. Extensive drug resistance during low-level HIV viraemia while taking NNRTI-based ART supports lowering the viral load threshold for regimen switch in resource-limited settings: a pre-planned analysis from the SESOTHO trial. J Antimicrob Chemother. 2021;76(5):1294-1298. DOI: 10.1093/jac/dkab025

2021
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Magnolini R, Senkoro E, Vanobberghen F, Weisser M. "Linkage to care" among people living with HIV - definition in the era of "universal test and treat" in a sub-Sahara African setting. Swiss Med Wkly. 2021;151:w20535. DOI: 10.4414/smw.2021.20535

2021
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Mapesi H, Gupta R, Wilson H.I, Lukau B, Amstutz A, Lyimo A, Muhairwe J, Senkoro E, Byakuzana T, Mphunyane M, Bresser M, Glass T.R, Lambiris M, Fink G, Gingo W, Battegay M, Paris D.H, Rohacek M, Vanobberghen F, Labhardt N.D, Burkard T, Weisser M. The coArtHA trial—identifying the most effective treatment strategies to control arterial hypertension in sub-Saharan Africa: study protocol for a randomized controlled trial. Trials. 2021;22:77. DOI: 10.1186/s13063-021-05023-z

2021
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Multerer L, Glass T.R, Vanobberghen F, Smith T. Analysis of contamination in cluster randomized trials of malaria interventions. Trials. 2021;22:613. DOI: 10.1186/s13063-021-05543-8

2021
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Vanobberghen F, Lweno O, Kümmerle A, Mwebi K.D, Asilia P, Simon B, Mswata S, Schmidlin S, Glass T.R, Daubenberger C, Tanner M, Meyer-Monard S. Efficacy and safety of intravenous ferric carboxymaltose compared with oral iron for the treatment of iron deficiency anaemia in women after childbirth in Tanzania: a parallelgroup, open-label, randomised controlled phase 3 trial. Lancet Glob Health. 2021;9(2):e189-e198. DOI: 10.1016/S2214-109X(20)30448-4

2021
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Vanobberghen F, Weisser M, Kasuga B, Katende A, Battegay M, Tanner M, Glass T.R, KIULARCO Study Group. Mortality in a cohort of people living with HIV in rural Tanzania, accounting for unseen mortality among those lost to follow-up. Am J Epidemiol. 2021(in press). DOI: 10.1093/aje/kwaa176

2021
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Amstutz A, Nsakala B.L, Vanobberghen F, Muhairwe J, Glass T.R, Namane T, Mpholo T, Battegay M, Klimkait T, Labhardt N.D. Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized controlled trial in Lesotho. PLoS Med. 2020;17(9):e1003325. DOI: 10.1371/journal.pmed.1003325

2020
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Kalinjuma A.V, Glass T.R, Weisser M, Myeya S.J, Kasuga B, Kisung'a Y, Sikalengo G, Katende A, Battegay M, Vanobberghen F, Kiularco Study Group. Prospective assessment of loss to follow-up: incidence and associated factors in a cohort of HIV-positive adults in rural Tanzania. J Int AIDS Soc. 2020;23(3):e25460. DOI: 10.1002/jia2.25460

2020
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Ndege R, Ngome O, Bani F, Temba Y, Wilson H, Vanobberghen F, Hella J, Gingo W, Sasamalo M, Mnzava D, Kimera N, Hiza H, Wigayi J, Mapesi H, Kato I.B, Mhimbira F, Reither K, Battegay M, Paris D.H, Weisser M, Rohacek M. Ultrasound in managing extrapulmonary tuberculosis: a randomized controlled two-center study. BMC Infect Dis. 2020;20:349. DOI: 10.1186/s12879-020-05073-9

2020
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Schlaeppi C, Vanobberghen F, Sikalengo G, Glass T.R, Ndege R.C, Foe G, Kümmerle A, Paris D.H, Battegay M, Marzolini C, Weisser M, Kilombero and Ulanga Antiretroviral Cohort (KIULARCO) study group. Prevalence and management of drug-drug interactions with antiretroviral treatment in 2069 people living with HIV in rural Tanzania: a prospective cohort study. HIV Med. 2020;21(1):53-63. DOI: 10.1111/hiv.12801

2020
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Vanobberghen F, Weiss H.A, Fuhr D.C, Sikander S, Afonso E, Ahmad I, Atif N, Bibi A, Bibi.T, Bilal S, de Sa A, D'Souza E, Joshi A, Korgaonkar P, Krishna R, Lazarus A, Liaqat R, Sharif M, Weobong B, Zaidi A, Zuliqar S, Patel V, Rahman A. Effectiveness of the Thinking Healthy Programme for perinatal depression delivered through peers: pooled analysis of two randomized controlled trials in India and Pakistan. J Affect Disord. 2020;265:660-668. DOI: 10.1016/j.jad.2019.11.110

2020
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Amstutz A, Lejone T.I, Khesa L, Muhairwe J, Nsakala B.L, Tlali K, Bresser M, Vanobberghen F, Kopo M, Kao M, Klimkait T, Battegay M, Labhardt N.D, Glass T.R. The HOSENG trial - effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on testing coverage: protocol of a cluster-randomized clinical trial in rural Lesotho. Trials. 2019;20:496. DOI: 10.1186/s13063-019-3469-2

2019
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Glass T.R, Motaboli L, Nsakala B, Lerotholi M, Vanobberghen F, Amstutz A, Lejone T.I, Muhairwe J, Klimkait T, Labhardt N.D. The viral load monitoring cascade in a resource-limited setting: a prospective multicentre cohort study after introduction of routine viral load monitoring in rural Lesotho. PLoS One. 2019;14(8):e0220337. DOI: 10.1371/journal.pone.0220337

2019
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Meister I, Assawasuwannakit P, Vanobberghen F, Penny M, Odermatt P, Sayasone S, Huwyler J, Tarning J, Keiser J. Pooled population pharmacokinetic analysis of tribendimidine for the treatment of Opisthorchis viverrini infections. Antimicrob Agents Chemother. 2019;63(4):e01391-18. DOI: 10.1128/AAC.01391-18

2019
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Amstutz A, Nsakala B.L, Vanobberghen F, Muhairwe J, Glass T.R, Achieng B, Sepeka M, Tlali K, Sao L, Thin K, Klimkait T, Battegay M, Labhardt N.D. SESOTHO trial ("Switch Either near Suppression Or THOusand") - switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel-group, open-label, r. BMC Infect Dis. 2018;18:76. DOI: 10.1186/s12879-018-2979-y

2018
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Luoga E, Vanobberghen F, Bircher R, Nyuri A, Ntamatungiro A.J, Mnzava D, Mollel G.J, Letang E, Battegay M, Weisser M, Gamell A. No HIV transmission from virally suppressed mothers during breastfeeding in rural Tanzania. J Acquir Immune Defic Syndr. 2018;79(1):e17-e20. DOI: 10.1097/QAI.0000000000001758

2018
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Tiono A, Ouédraogo A, Ouattara D, Bougouma E.C, Coulibaly S, Diarra A, Faragher B, Guelbeogo M.W, Grisales N, Ouédraogo I.N, Ouédraogo Z.A, Pinder M, Sanon S, Smith T, Vanobberghen F, Sagnon N, Ranson H, Lindsay S.W. Efficacy of Olyset Duo, a bednet containing pyriproxyfen and permethrin, versus a permethrin-only net against clinical malaria in an area with highly pyrethroid-resistant vectors in rural Burkina Faso: a cluster-randomised controlled trial. Lancet. 2018;392(10147):569-580. DOI: 10.1016/S0140-6736(18)31711-2

2018
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Letang E, Verdastus Kalinjuma A, Glass T.R, Gamell A, Mapesi H, Sikalengo G.R, Luwanda L.B, Mnzava D, Ntamatungiro A.J, Ndaki R, Francis G, Vanobbergen F, Furrer H, Klimkait T, Felger I, Tanner M, Hatz C, Weisser M, Battegay M, KIULARCO Study Group. Cohort profile: the Kilombero and Ulanga Antiretroviral Cohort (KIULARCO): a prospective HIV cohort in rural Tanzania. Swiss Med Wkly. 2017;147:w14485. DOI: 10.4414/smw.2017.14485

2017
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Vanobberghen F, Letang E, Gamell A, Mnzava D.K, Faini D, Luwanda L.B, Mapesi H, Mwamelo K, Sikalengo G, Tanner M, Hatz C, Furrer H, Battegay M, Glass T.R, Kiularco Study Group. A decade of HIV care in rural Tanzania: trends in clinical outcomes and impact of clinic optimisation in an open, prospective cohort. PLoS One. 2017;12(7):e0180983. DOI: 10.1371/journal.pone.0180983

2017
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Meister I, Kovac J, Duthaler U, Odermatt P, Huwyler J, Vanobberghen F, Sayasone S, Keiser J. Pharmacokinetic study of praziquantel enantiomers and its main metabolite R-trans-4-OH-PZQ in plasma, blood and dried blood spots in Opisthorchis viverrini-infected patients. PLoS Negl Trop Dis. 2016;10(5):e0004700. DOI: 10.1371/journal.pntd.0004700

2016
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Vanobberghen F, Penny M.A, Duthaler U, Odermatt P, Sayasone S, Keiser J, Tarning J. Population pharmacokinetic modeling of tribendimidine metabolites in Opisthorchis viverrini-infected adults. Antimicrob Agents Chemother. 2016;60(10):5695-5704. DOI: 10.1128/AAC.00655-16

2016
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Meister I, Vanobberghen F, Penny M.A, Sayasone S, Phongluxa K, Odermatt P, Duthaler U, Leonidova A, Huwyler J, Keiser J. Population pharmacokinetics of the novel anthelminthic tribendimidine in Opisthorchis viverrini infected patients in Lao PDR. Trop Med Int Health, 2015;20(Suppl. 1):303. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

2015
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Vanobberghen F, Letang E, Gamell A, John A, Faini D, Bonaventure L, Mapesi H, Mwamelo K, Sikalengo G, Tanner M, Hatz C, Furrer H, Battegay M, Glass T. Challenges in estimating death and retention rates in a longitudinal cohort of HIV-infected persons in rural Tanzania. Trop Med Int Health, 2015;20(Suppl. 1):9. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

2015
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Chofle A.A, Jaka H, Koy M, Smart L.R, Kabangila R, Ewings F.M, Mazigo H.D, Johnson W.D, Fitzgerald D.W, Peck R.N, Downs J.A. Oesophageal varices, schistosomiasis, and mortality among patients admitted with haematemesis in Mwanza, Tanzania: a prospective cohort study. BMC Infect Dis. 2014;14:303. DOI: 10.1186/1471-2334-14-303

2014
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Ewings F.M, Ford D, Walker A.S, Carpenter J, Copas A. Optimal CD4 count for initiating HIV treatment: impact of CD4 observation frequency and grace periods, and performance of dynamic marginal structural models. Epidemiology. 2014;25(2):194-202. DOI: 10.1097/EDE.0000000000000043

2014
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Francis S.C, Ao T.T, Vanobberghen F.M, Chilongani J, Hashim R, Andreasen A, Watson-Jones D, Changalucha J, Kapiga S, Hayes R.J. Epidemiology of curable sexually transmitted infections among women at increased risk for HIV in northwestern Tanzania: inadequacy of syndromic management. PLoS One. 2014;9(7):e101221. DOI: 10.1371/journal.pone.0101221

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Frater J, Ewings F, Hurst J, Brown H, Robinson N, Fidler S, Babiker A, Weber J, Porter K, Phillips R.E. HIV-1-specific CD4(+) responses in primary HIV-1 infection predict disease progression. AIDS. 2014;28(5):699-708. DOI: 10.1097/QAD.0000000000000130

2014
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Peck R, Mghamba J, Vanobberghen F, Kavishe B, Rugarabamu V, Smeeth L, Hayes R, Grosskurth H, Kapiga S. Preparedness of Tanzanian health facilities for outpatient primary care of hypertension and diabetes: a cross-sectional survey. Lancet Glob Health. 2014;2(5):e285-e292. DOI: 10.1016/S2214-109X(14)70033-6

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Fidler S, Porter K, Ewings F, Frater J, Ramjee G, Cooper D, Rees H, Fisher M, Schechter M, Kaleebu P, Tambussi G, Kinloch S, Miro J.M, Kelleher A, McClure M, Kaye S, Gabriel M, Phillips R, Weber J, Babiker A. Short-course antiretroviral therapy in primary HIV infection. N Engl J Med. 2013;368(3):207-217. DOI: 10.1056/NEJMoa1110039

2013
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Kapiga S.H, Ewings F.M, Ao T, Chilongani J, Mongi A, Baisley K, Francis S, Andreasen A, Hashim R, Watson-Jones D, Changalucha J, Hayes R. The epidemiology of HIV and HSV-2 infections among women participating in microbicide and vaccine feasibility studies in Northern Tanzania. PLoS One. 2013;8(7):e68825. DOI: 10.1371/journal.pone.0068825

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Njai H.F, Ewings F.M, Lyimo E, Foulongne V, Ngerageza D, Mongi A, Ssemwanga D, Andreasen A, Nyombi B, Ao T, Michael D, Urassa M, Todd J, Zaba B, Changalucha J, Hayes R, Kapiga S.H. Deciphering the complex distribution of human immunodeficiency virus type 1 subtypes among different cohorts in Northern Tanzania. PLoS One. 2013;8(12):e81848. DOI: 10.1371/journal.pone.0081848

2013
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Ewings F.M. Practical and theoretical considerations of the application of marginal structural models to estimate causal effects of treatment in HIV infection. London: University College London, 2012. PhD Thesis

2012
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Hamlyn E, Ewings F.M, Porter K, Cooper D.A, Tambussi G, Schechter M, Pedersen C, Okulicz J.F, McClure M, Babiker A, Weber J, Fidler S. Plasma HIV viral rebound following protocol-indicated cessation of ART commenced in primary and chronic HIV infection. PLoS One. 2012;7(8):e43754. DOI: 10.1371/journal.pone.0043754

2012
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Burger D, Ewings F, Kabamba D, L'homme R, Mulenga V, Kankasa C, Thomason M, Gibb D.M, Chintu C, Walker A.S. Limited sampling models to predict the pharmacokinetics of nevirapine, stavudine, and lamivudine in HIV-infected children treated with pediatric fixed-dose combination tablets. Ther Drug Monit. 2010;32(3):369-372. DOI: 10.1097/FTD.0b013e3181d75e47

2010
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Ewings F.M, Bhaskaran K, McLean K, Hawkins D, Fisher M, Fidler S, Gilson R, Nock D, Brettle R, Johnson M, Phillips A, Porter K. Survival following HIV infection of a cohort followed up from seroconversion in the UK. AIDS. 2008;22(1):89-95. DOI: 10.1097/QAD.0b013e3282f3915e

2008
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L'homme R.F, Kabamba D, Ewings F.M, Mulenga V, Kankasa C, Thomason M.J, Walker A.S, Chintu C, Burger D.M, Gibb D.M. Nevirapine, stavudine and lamivudine pharmacokinetics in African children on paediatric fixed-dose combination tablets. AIDS. 2008;22(5):557-565. DOI: 10.1097/QAD.0b013e3282f4a208

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Ellis J.C, L'homme R.F, Ewings F.M, Mulenga V, Bell F, Chileshe R, Molyneux E, Abernethy J, van Oosterhout J.J, Chintu C, Walker A.S, Gibb D.M, Burger D.M. Nevirapine concentrations in HIV-infected children treated with divided fixed-dose combination antiretroviral tablets in Malawi and Zambia. Antivir Ther. 2007;12(2):253-260

2007
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