Camponovo F, Ockenhouse C.F, Lee C, Penny M.A. Mass campaigns combining antimalarial drugs and anti-infective vaccines as seasonal interventions for malaria control, elimination and prevention of resurgence: a modelling study. BMC Infect Dis. 2019;19:920. DOI: 10.1186/s12879-019-4467-4

2019
Journal Article
PubMed (31664924)
Link

Dietler D, Leuenberger A, Bempong N.E, Campbell-Lendrum D, Cramer C, Eggen R.I.L, Erismann S, Ferazzi S, Flahault A, Fletcher H.A, Fuhrer B, Fuhrimann S, Greter H, Heerdegen A.C, Leach M, Leissing A, Lilje J, Penny M.A, Prytherch H, Staudacher P, Vounatsou P, Weiss F, Wiedermann R, Winkler M.S, Zhou X.N, Utzinger J. Health in the 2030 Agenda for Sustainable Development: from framework to action, transforming challenges into opportunities. J Glob Health. 2019;9(2):020201. DOI: 10.7189/jogh.09.020201

2019
Journal Article
PubMed (31489184)
Link

Lee T.E, Penny M.A. Identifying key factors of the transmission dynamics of drug-resistant malaria. J Theor Biol. 2019;462:210-220. DOI: 10.1016/j.jtbi.2018.10.050

2019
Journal Article
PubMed (30381147)

Meister I, Assawasuwannakit P, Vanobberghen F, Penny M, Odermatt P, Sayasone S, Huwyler J, Tarning J, Keiser J. Pooled population pharmacokinetic analysis of tribendimidine for the treatment of Opisthorchis viverrini infections. Antimicrob Agents Chemother. 2019;63(4):e01391-18. DOI: 10.1128/AAC.01391-18

2019
Journal Article
PubMed (30718244)
Link

Smith T.A, Pemberton-Ross P, Penny M.A, Chitnis N. Resurgence of malaria infection after mass treatment: a simulation study. Malar J. 2019;18:409. DOI: 10.1186/s12936-019-3019-0

2019
Journal Article
PubMed (31805947)
Link

Stader F, Kinvig H, Penny M.A, Battegay M, Siccardi M, Marzolini C. Physiologically based pharmacokinetic modelling to identify pharmacokinetic parameters driving drug exposure changes in the elderly. Clin Pharmacokinet. 2019(in press). DOI: 10.1007/s40262-019-00822-9

2019
Journal Article
PubMed (31583609)

Stader F, Penny M.A, Siccardi M, Marzolini C. A comprehensive framework for physiologically based pharmacokinetic modelling in Matlab®. CPT Pharmacometrics Syst Pharmacol. 2019;8:444-459. DOI: 10.1002/psp4.12399

2019
Journal Article
PubMed (30779335)
Link

Stader F, Siccardi M, Battegay M, Kinvig H, Penny M.A, Marzolini C. Repository describing an aging population to inform physiologically based pharmacokinetic models considering anatomical, physiological, and biological age-dependent changes. Clin Pharmacokinet. 2019;58(4):483-501. DOI: 10.1007/s40262-018-0709-7

2019
Journal Article
PubMed (30128967)

Ali A.M, Penny M.A, Smith T.A, Workman L, Sasi P, Adjei G.O, Aweeka F, Kiechel J.R, Jullien V, Rijken M.J, McGready R, Mwesigwa J, Kristensen K, Stepniewska K, Tarning J, Barnes K.I, Denti P, WWARN Amodiaquine PK Study Group. Population pharmacokinetics of the antimalarial amodiaquine: a pooled analysis to optimize dosing. Antimicrob Agents Chemother. 2018;62(10):e02193-17. DOI: 10.1128/AAC.02193-17

2018
Journal Article
PubMed (30038039)
Link

Chitnis N, Schapira A, Schindler C, Penny M, Smith T. Mathematical analysis to prioritise strategies for malaria elimination. J Theor Biol. 2018;455:118-130. DOI: 10.1016/j.jtbi.2018.07.007

2018
Journal Article
PubMed (30006002)
Link

Brady O, Slater H.C, Pemberton-Ross P, Wenger E, Maude R.J, Ghani A.C, Penny M.A, Gerardin J, White L.J, Chitnis N, Aguas R, Hay S.I, Smith D.L, Stuckey E.M, Okiro E.A, Smith T.A, Okell L.C. Role of mass drug administration in elimination of Plasmodium falciparum malaria: a consensus modelling study. Lancet Glob Health. 2017;5(7):e680-e687. DOI: 10.1016/S2214-109X(17)30220-6

2017
Journal Article
PubMed (28566213)
Link

Brady O.J, Slater H.C, Pemberton-Ross P, Wenger E, Maude R.J, Ghani A.C, Penny M.A, Gerardin J, White L.J, Chitnis N, Aguas R, Hay S.I, Smith D.L, Stuckey E.M, Smith T.A, Okell L.C. Model citizen – Authors' reply. Lancet Glob Health. 2017;5(10):e974. DOI: 10.1016/S2214-109X(17)30338-8

2017
Journal Item

Camponovo F, Bever C.A, Galactionova K, Smith T.A, Penny M.A. Incidence and admission rates for severe malaria and their impact on mortality in Africa. Malar J. 2017;16:1. DOI: 10.1186/s12936-016-1650-6

2017
Journal Article
PubMed (28049519)
Link

Galactionova K, Smith T.A, de Savigny D, Penny M.A. State of inequality in malaria intervention coverage in sub-Saharan African countries. BMC Med. 2017;15:185. DOI: 10.1186/s12916-017-0948-8

2017
Journal Article
PubMed (29041940)
Link

Galactionova K, Tediosi F, Camponovo F, Smith T.A, Gething P.W, Penny M.A. Country specific predictions of the cost-effectiveness of malaria vaccine RTS,S/AS01 in endemic Africa. Vaccine. 2017;35(1):53-60. DOI: 10.1016/j.vaccine.2016.11.042

2017
Journal Article
PubMed (27890400)

Penny M.A, Smith T. Plasmodium falciparum mortality in Africa between 1990 and 2015. N Engl J Med. 2017;376(25):2493-2494. DOI: 10.1056/NEJMc1701144

2017
Journal Item
PubMed (28636857)

Smith T, Chitnis N, Penny M. Predictive malaria epidemiology: modeling malaria infection dynamics and impact of control interventions. In: Kremsner P.G,Krishna S, eds. Encyclopedia of malaria, 1-7. New York: Springer, 2017. DOI: 10.1007/978-1-4614-8757-9_80-1

2017
Book Section

Smith T.A, Chitnis N, Penny M, Tanner M. Malaria modeling in the era of eradication. Cold Spring Harb Perspect Med. 2017;7(4):a025460. DOI: 10.1101/cshperspect.a025460

2017
Journal Article
PubMed (28003280)

Duthaler U, Sayasone S, Vanobbergen F, Penny M, Odermatt P, Huwyler J, Keiser J. Single ascending dose pharmacokinetic study of tribendimidine in Opisthorchis viverrini-infected patients. Antimicrob Agents Chemother. 2016;60(10):5705-5715. DOI: 10.1128/AAC.00992-16

2016
Journal Article
PubMed (27431234)

Penny M.A, Verity R, Bever C.A, Sauboin C, Galactionova K, Flasche S, White M.T, Wenger E.A, Van de Velde N, Pemberton-Ross P, Griffin J.T, Smith T.A, Eckhoff P.A, Muhib F, Jit M, Ghani A.C. Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine: a systematic comparison of predictions from four mathematical models. Lancet. 2016;387(10016):367-375. DOI: 10.1016/S0140-6736(15)00725-4

2016
Journal Article
PubMed (26549466)
Link

Tediosi F, Penny M. Evidence for optimal allocation of malaria interventions in Africa [Comment]. Lancet Global Health. 2016;4(7):e432-e433. DOI: 10.1016/S2214-109X(16)30108-5

2016
Journal Item
PubMed (27283763)

Vanobberghen F, Penny M.A, Duthaler U, Odermatt P, Sayasone S, Keiser J, Tarning J. Population pharmacokinetic modeling of tribendimidine metabolites in Opisthorchis viverrini-infected adults. Antimicrob Agents Chemother. 2016;60(10):5695-5704. DOI: 10.1128/AAC.00655-16

2016
Journal Article
PubMed (27431233)

Bhatt S, Weiss D.J, Cameron E, Bisanzio D, Mappin B, Dalrymple U, Battle K.E, Moyes C.L, Henry A, Eckhoff P.A, Wenger E.A, Briët O, Penny M.A, Smith T.A, Bennett A, Yukich J, Eisele T.P, Griffin J.T, Fergus C.A, Lynch M, Lindgren F, Cohen J.M, Murray C.L, Smith D.L, Hay S.I, Cibulskis R.E, Gething P.W. The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015. Nature. 2015;526(7572):207-211. DOI: 10.1038/nature15535

2015
Journal Article
PubMed (26375008)

Cameron E, Battle K.E, Bhatt S, Weiss D.J, Bisanzio D, Mappin B, Dalrymple U, Hay S.I, Smith D.L, Griffin J.T, Wenger E.A, Eckhoff P.A, Smith T.A, Penny M.A, Gething P.W. Defining the relationship between infection prevalence and clinical incidence of Plasmodium falciparum malaria. Nat Commun. 2015;6:8170. DOI: 10.1038/ncomms9170

2015
Journal Article
PubMed (26348689)

Chitnis N, Schapira A, Schindler C, Penny M, Smith T. Where to start malaria elimination: core or fringes?. Trop Med Int Health, 2015;20(Suppl. 1):14

2015
Conference Paper

Meister I, Vanobberghen F, Penny M.A, Sayasone S, Phongluxa K, Odermatt P, Duthaler U, Leonidova A, Huwyler J, Keiser J. Population pharmacokinetics of the novel anthelminthic tribendimidine in Opisthorchis viverrini infected patients in Lao PDR. Trop Med Int Health, 2015;20(Suppl. 1):303. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

2015
Conference Paper

Okell L, Slater H, Ghani A, Pemberton-Ross P, Smith T.A, Chitnis N, Penny M.A, Wenger E, Garardin J, Maude R, Aguas R, White L, Brady O, Hay S, Okiro E, Kern S. Consensus modelling evidence to support the design of mass drug administration programmes. Geneva: World Health Organization, 2015

2015
Report

Pemberton-Ross P, Smith T.A, Hodel E.M, Kay K, Penny M.A. Age-shifting in malaria incidence as a result of induced immunological deficit: a simulation study. Malar J. 2015;14:287. DOI: 10.1186/s12936-015-0805-1

2015
Journal Article
PubMed (26206255)
Link

Penny M.A, Galactionova K, Pemberton-Ross P, Smith T.A. The public health impact and cost-effectiveness of the RTS, S malaria vaccine candidate in malaria endemic Africa: estimates based on phase III clinical trial results. Trop Med Int Health, 2015;20(Suppl. 1):102-103. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

2015
Conference Paper

Penny M.A, Galactionova K, Pemberton-Ross P, Thomas A.S, Verity R, White M, Griffin J, Ghani A, Bever C, Wenger E, Sauboin C, Van de Velde N, Flasche S. The public health impact and cost-effectiveness malaria vaccine RTS,S/AS01 prior to a WHO policy recommendation : a systematic comparison of predictions and mathematical models. Basel: Swiss Tropical and Public Health Institute, 2015

2015
Report

Penny M.A, Galactionova K, Tarantino M, Tanner M, Smith T.A. The public health impact of malaria vaccine RTS,S in malaria endemic Africa: country-specific predictions using 18 month follow-up Phase III data and simulation models. BMC Med. 2015;13:170. DOI: 10.1186/s12916-015-0408-2

2015
Journal Article
PubMed (26219380)
Link

Penny M.A, Maire N, Bever C.A, Pemberton-Ross P, Briët O.J.T, Smith D.L, Gething P.W, Smith T.A. Distribution of malaria exposure in endemic countries in Africa considering country levels of effective treatment. Malar J. 2015;14:384. DOI: 10.1186/s12936-015-0864-3

2015
Journal Article
PubMed (26437798)
Link

Penny M.A, Pemberton-Ross P, Smith T.A. The time-course of protection of the RTS,S vaccine against malaria infections and clinical disease. Malar J. 2015;14:437. DOI: 10.1186/s12936-015-0969-8

2015
Journal Article
PubMed (26537608)
Link

Galactionova K, Tediosi F, Smith T.A, Penny M.A. Projected cost-effectiveness of RTS,S vaccination in 43 sub-Saharan African countries. Am J Trop Med Hyg, 2014;91(5 Suppl. 1):484-485

2014
Conference Paper

Galactionova K, Tediosi F, Smith T.A, Penny M.A. Distribution impact of RTS,S vaccination in sub-saharan Africa: implications for policy implementation. Am J Trop Med Hyg, 2014;91(5 Suppl. 1):303

2014
Conference Paper

Lutambi A.M, Chitnis N, Briët O.J, Smith T.A, Penny M.A. Clustering of vector control interventions has important consequences for their effectiveness: a modelling study. PLoS One. 2014;9(5):e97065. DOI: 10.1371/journal.pone.0097065

2014
Journal Article
PubMed (24823656)
Link

Penny M.A, Pemberton-Ross P, Smith T. The reltive improtance of malaria vaccine properties. Am J Trop Med Hyg, 2014;91(5 Suppl. 1):305

2014
Conference Paper

Smith T, Penny M, Chitnis N. Where to start in eliminating an infectious agent?. Am J Trop Med Hyg, 2014;89(5 Suppl.):390

2014
Conference Paper

Briët O.J, Penny M.A. Repeated mass distributions and continuous distribution of long-lasting insecticidal nets: modelling sustainability of health benefits from mosquito nets, depending on case management. Malar J. 2013;12:401. DOI: 10.1186/1475-2875-12-401

2013
Journal Article
PubMed (24200296)
Link

Briët O.J.T, Penny M.A, Hardy D, Awolola T.S, Van Bortel W, Corbel V, Dabiré R.K, Etang J, Koudou B.G, Tungu P.K, Chitnis N. Effects of pyrethroid resistance on the cost effectiveness of a mass distribution of long-lasting insecticidal nets: a modelling study. Malar J. 2013;12:77. DOI: 10.1186/1475-2875-12-77

2013
Journal Article
PubMed (23442575)
Link