Amstutz A, Matsela L, Lejone T.I, Kopo M, Glass T.R, Labhardt N.D. Reaching absent and refusing individuals during home-based HIV testing through self-testing-at what cost?. Front Med (Lausanne). 2021;8:653677. DOI: 10.3389/fmed.2021.653677

2021
Journal Article
PubMed (34268321)
Link

Brown J.A, Amstutz A, Nsakala B.L, Seeburg U, Vanobberghen F, Muhairwe J, Klimkait T, Daniel Labhardt N. Extensive drug resistance during low-level HIV viraemia while taking NNRTI-based ART supports lowering the viral load threshold for regimen switch in resource-limited settings: a pre-planned analysis from the SESOTHO trial. J Antimicrob Chemother. 2021;76(5):1294-1298. DOI: 10.1093/jac/dkab025

2021
Journal Article
PubMed (33599270)

Brown J.A, Mbunkah H.A, Lejone T.I, Ringera I, Cheleboi M, Klimkait T, Metzner K.J, Gunthard H.F, Labhardt N.D, Kouyos R.D, Tschumi N. Emergence of human immunodeficiency virus-1 drug resistance during the 3-month World Health Organization-recommended enhanced adherence counseling period in the CART-1 cohort study. Open Forum Infect Dis. 2021;8(5):ofab046. DOI: 10.1093/ofid/ofab046

2021
Journal Article
PubMed (34046513)
Link

Chernet A, Probst-Hensch N, Sydow V, Paris D.H, Labhardt N.D. Mental health and resilience among Eritrean refugees at arrival and one-year post-registration in Switzerland: a cohort study. BMC Res Notes. 2021;14:281. DOI: 10.1186/s13104-021-05695-5

2021
Journal Article
PubMed (34294120)
Link

Erismann S, Pesantes M.A, Beran D, Leuenberger A, Farnham A, Berger Gonzalez de White M, Labhardt N.D, Tediosi F, Akweongo P, Kuwawenaruwa A, Zinsstag J, Brugger F, Somerville C, Wyss K, Prytherch H. How to bring research evidence into policy? Synthesizing strategies of five research projects in low-and middle-income countries. Health Res Policy Syst. 2021;19:29. DOI: 10.1186/s12961-020-00646-1

2021
Journal Article
PubMed (33676518)
Link

Mapesi H, Gupta R, Wilson H.I, Lukau B, Amstutz A, Lyimo A, Muhairwe J, Senkoro E, Byakuzana T, Mphunyane M, Bresser M, Glass T.R, Lambiris M, Fink G, Gingo W, Battegay M, Paris D.H, Rohacek M, Vanobberghen F, Labhardt N.D, Burkard T, Weisser M. The coArtHA trial—identifying the most effective treatment strategies to control arterial hypertension in sub-Saharan Africa: study protocol for a randomized controlled trial. Trials. 2021;22:77. DOI: 10.1186/s13063-021-05023-z

2021
Journal Article
PubMed (33478567)
Link

Amstutz A, Brown J.A, Ringera I, Muhairwe J, Lejone T.I, Klimkait T, Glass T.R, Labhardt N.D. Engagement in care, viral suppression, drug resistance and reasons for non-engagement after home-based same-day ART initiation in Lesotho: a two-year follow-up of the CASCADE trial. Clin Infect Dis. 2020;71(10):2608-2614. DOI: 10.1093/cid/ciz1126

2020
Journal Article
PubMed (31781759)
Link

Amstutz A, Kopo M, Lejone T.I, Khesa L, Kao M, Muhairwe J, Glass T.R, Labhardt N.D. "If it is left, it becomes easy for me to get tested": use of oral self-tests and community health workers to maximize the potential of home-based HIV testing among adolescents in Lesotho. J Int AIDS Soc. 2020;23(Suppl. 5):e25563. DOI: 10.1002/jia2.25563

2020
Journal Article
PubMed (32869527)
Link

Amstutz A, Lejone T.I, Khesa L, Muhairwe J, Bresser M, Vanobberghen F, Kopo M, Kao M, Nsakala B.L, Tlali K, Klimkait T, Battegay M, Labhardt N.D, Glass T.R. Home-based oral self-testing for absent and declining individuals during a door-to-door HIV testing campaign in rural Lesotho (HOSENG): a cluster-randomised trial. Lancet HIV. 2020;7(11):e752-e761. DOI: 10.1016/S2352-3018(20)30233-2

2020
Journal Article
PubMed (33045193)

Amstutz A, Nsakala B.L, Cheleboi M, Lejone T.I, Hobbins M.A, Battegay M, Klimkait T, Labhardt N.D. Low rates of active hepatitis B and C infections among adults and children living with HIV and taking antiretroviral therapy: a multicenter screening study in Lesotho. J Med Virol. 2020;92:3857–3861. DOI: 10.1002/jmv.25970

2020
Journal Item
PubMed (32369206)

Amstutz A, Nsakala B.L, Vanobberghen F, Muhairwe J, Glass T.R, Namane T, Mpholo T, Battegay M, Klimkait T, Labhardt N.D. Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized controlled trial in Lesotho. PLoS Med. 2020;17(9):e1003325. DOI: 10.1371/journal.pmed.1003325

2020
Journal Article
PubMed (32936795)
Link

Blum J, Chaney M, Mudji J, Mfungwa J.K, Rice T, Labhardt N.D. Glycaemic control among patients with type 2 diabetes followed in a rural African primary care setting - a reality check in the Democratic Republic of Congo. Prim Care Diabetes. 2020;14(2):139-146. DOI: 10.1016/j.pcd.2019.08.002

2020
Journal Article
PubMed (31455548)

Brown J.A, Ringera I, Luoga E, Cheleboi M, Kimera N, Muhairwe J, Kayembe B.P, Molapo Hlasoa M, Kabundi L, Yav C.W.D, Mothobi B, Thahane L, Amstutz A, Bachmann N, Mollel G.J, Bresser M, Glass T.R, Paris D.H, Klimkait T, Weisser M, Labhardt N.D. Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and adolescents living with HIV in Lesotho and Tanzania. BMC Infect Dis. 2020;20:773. DOI: 10.1186/s12879-020-05491-9

2020
Journal Article
PubMed (33076866)
Link

Lejone T.I, Kopo M, Bachmann N, Brown J.A, Glass T.R, Muhairwe J, Matsela T, Scherrer R, Chere L, Namane T, Labhardt N.D, Amstutz A. PEBRA trial - effect of a peer-educator coordinated preference-based ART service delivery model on viral suppression among adolescents and young adults living with HIV: protocol of a cluster-randomized clinical trial in rural Lesotho. BMC Public Health. 2020;20(1):425. DOI: 10.1186/s12889-020-08535-6

2020
Journal Article
PubMed (32228531)
Link

Smit M, Marinosci A, Nicoletti G.J, Perneger T, Ragozzino S, Andrey D.O, Stoeckle M, Jacquerioz F, Lebowitz D, Agoritsas T, Meyer B, Spechbach H, Salamun J, Back M, Schaubhut C, Fuchs S, Decosterd L, Battegay M, Guessous I, Chappuis F, Kaiser L, Labhardt N.D, Calmy A. Efficacy of pragmatic same-day ring prophylaxis for adult individuals exposed to SARS-CoV-2 in Switzerland (COPEP): protocol of an open-label cluster randomised trial. BMJ Open. 2020;10(11):e040110. DOI: 10.1136/bmjopen-2020-040110

2020
Journal Article
PubMed (33184083)
Link

Amstutz A, Lejone T.I, Khesa L, Muhairwe J, Nsakala B.L, Tlali K, Bresser M, Tediosi F, Kopo M, Kao M, Klimkait T, Battegay M, Glass T.R, Labhardt N.D. VIBRA trial - effect of village-based refill of ART following home-based same-day ART initiation vs clinic-based ART refill on viral suppression among individuals living with HIV: protocol of a cluster-randomized clinical trial in rural Lesotho. Trials. 2019;20:522. DOI: 10.1186/s13063-019-3510-5

2019
Journal Article
PubMed (31439004)
Link

Amstutz A, Lejone T.I, Khesa L, Muhairwe J, Nsakala B.L, Tlali K, Bresser M, Vanobberghen F, Kopo M, Kao M, Klimkait T, Battegay M, Labhardt N.D, Glass T.R. The HOSENG trial - effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on testing coverage: protocol of a cluster-randomized clinical trial in rural Lesotho. Trials. 2019;20:496. DOI: 10.1186/s13063-019-3469-2

2019
Journal Article
PubMed (31409421)
Link

Bachmann N, von Braun A, Labhardt N.D, Kadelka C, Gunthard H.F, Sekaggya-Wiltshire C, Castelnuovo B, Kambugu A, Lejone T.I, Boni J, Yerly S, Perreau M, Klimkait T, Kouyos R.D, Fehr J, Swiss HIV Cohort Study. Importance of routine viral load monitoring: higher levels of resistance at ART failure in Uganda and Lesotho compared with Switzerland. J Antimicrob Chemother. 2019;74(2):468-472. DOI: 10.1093/jac/dky436

2019
Journal Article
PubMed (30476115)

Chernet A, Probst-Hensch N, Sydow V, Paris D.H, Neumayr A, Labhardt N.D. Cardiovascular diseases risk factors among recently arrived Eritrean refugees in Switzerland. BMC Res Notes. 2019;12:668. DOI: 10.1186/s13104-019-4715-0

2019
Journal Article
PubMed (31639048)
Link

Courlet P, Decosterd L.A, Brown J.A, Alves Saldanha S, Marzolini C, Cavassini M, Stoeckle M, Csajka C, Labhardt N.D, Calmy A, Swiss HIV Cohort Study. Emtricitabine and lamivudine concentrations in saliva: a simple suitable test for treatment adherence. J Antimicrob Chemother. 2019;74(8):2468-2470. DOI: 10.1093/jac/dkz181

2019
Journal Article
PubMed (31065722)

Glass T.R, Motaboli L, Nsakala B, Lerotholi M, Vanobberghen F, Amstutz A, Lejone T.I, Muhairwe J, Klimkait T, Labhardt N.D. The viral load monitoring cascade in a resource-limited setting: a prospective multicentre cohort study after introduction of routine viral load monitoring in rural Lesotho. PLoS One. 2019;14(8):e0220337. DOI: 10.1371/journal.pone.0220337

2019
Journal Article
PubMed (31461455)
Link

Labhardt N.D, Ringera I, Lejone T.I, Amstutz A, Klimkait T, Muhairwe J, Glass T.R. Effect and cost of two successive home visits to increase HIV testing coverage: a prospective study in Lesotho, Southern Africa. BMC Public Health. 2019;19:1441. DOI: 10.1186/s12889-019-7784-z

2019
Journal Article
PubMed (31676001)
Link

Melamed S, Chernet A, Labhardt N.D, Probst-Hensch N, Pfeiffer C. Social resilience and mental health among Eritrean asylum-seekers in Switzerland. Qual Health Res. 2019;29(2):222-236. DOI: 10.1177/1049732318800004

2019
Journal Article
PubMed (30222038)

Neumayr A, Chernet A, Sydow V, Kling K, Künzli E, Marti H, Paris D.H, Nickel B, Labhardt N.D. Performance of the point-of-care circulating cathodic antigen (POC-CCA) urine cassette test for follow-up after treatment of S. mansoni infection in Eritrean refugees. Travel Med Infect Dis. 2019;28:59-63. DOI: 10.1016/j.tmaid.2018.09.004

2019
Journal Article
PubMed (30236539)

Staehelin C, Chernet A, Sydow V, Piso R.J, Suter-Riniker F, Funez S, Nickel B, Paris D.H, Labhardt N.D. Seroprotection rates of vaccine-preventable diseases among newly arrived Eritrean asylum seekers in Switzerland: a cross-sectional study. J Travel Med. 2019;26(6):taz035. DOI: 10.1093/jtm/taz035

2019
Journal Article
PubMed (31094415)

Amstutz A, Nsakala B.L, Vanobberghen F, Muhairwe J, Glass T.R, Achieng B, Sepeka M, Tlali K, Sao L, Thin K, Klimkait T, Battegay M, Labhardt N.D. SESOTHO trial ("Switch Either near Suppression Or THOusand") - switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel-group, open-label, r. BMC Infect Dis. 2018;18:76. DOI: 10.1186/s12879-018-2979-y

2018
Journal Article
PubMed (29433430)
Link

Chernet A, Neumayr A, Hatz C, Kling K, Sydow V, Rentsch K, Utzinger J, Probst-Hensch N, Marti H, Nickel B, Labhardt N.D. Spectrum of infectious diseases among newly arrived Eritrean refugees in Switzerland: a cross-sectional study. Int J Public Health. 2018;63(2):233-239. DOI: 10.1007/s00038-017-1034-x

2018
Journal Article
PubMed (28924741)

Chernet A, Utzinger J, Sydow V, Probst-Hensch N, Paris D.H, Labhardt N.D, Neumayr A. Prevalence rates of six selected infectious diseases among African migrants and refugees: a systematic review and meta-analysis. Eur J Clin Microbiol Infect Dis. 2018;37(4):605-619. DOI: 10.1007/s10096-017-3126-1

2018
Journal Article
PubMed (29080108)

Labhardt N.D, Ringera I, Lejone T.I, Klimkait T, Muhairwe J, Amstutz A, Glass T.R. Effect of offering same-day ART vs usual health facility referral during home-based HIV testing on linkage to care and viral suppression among adults with HIV in Lesotho: the CASCADE randomized clinical trial. JAMA. 2018;319(11):1103-1112. DOI: 10.1001/jama.2018.1818

2018
Journal Article
PubMed (29509839)

Lejone T.I, Ringera I, Cheleboi M, Wagner S, Muhairwe J, Klimkait T, Labhardt N.D. The treatment cascade in children with unsuppressed viral load - a reality check in rural Lesotho, Southern Africa. J Acquir Immune Defic Syndr. 2018;77(3):250-256. DOI: 10.1097/QAI.0000000000001597

2018
Journal Article
PubMed (29189416)

Neumayr A, Stöckle M, Künzli E, Kling K, Sydow V, Labhardt N, Beck B, Blum J, Paris D.H. Fieber bei Reiserückkehrern. Swiss Med Wkly. 2018;16:345-354. DOI: 10.4414/smf.2018.03240

2018
Journal Article

Chernet A, Hensch N.P, Kling K, Sydow V, Hatz C, Paris D.H, Rentsch K, Nickel B, Neumayr A, Labhardt N.D. Serum 25-hydroxyvitamin D levels and intramuscular vitamin D3 supplementation among Eritrean migrants recently arrived in Switzerland. Swiss Med Wkly. 2017;147:w14568. DOI: 10.4414/smw.2017.14568

2017
Journal Article
PubMed (29282703)
Link

Chernet A, Kling K, Sydow V, Künzli E, Hatz C, Utzinger J, van Lieshout L, Marti H, Nickel B, Labhardt N.D, Neumayr A. Accuracy of diagnostic tests for Schistosoma mansoni infection in asymptomatic Eritrean refugees: serology and POC-CCA against stool microscopy. Clin Infect Dis. 2017;65(4):568-574. DOI: 10.1093/cid/cix366

2017
Journal Article
PubMed (28430889)

Chernet A, Probst-Hensch N, Neumayr A, Kling K, Rentsch K, Hatz C, Labhardt N. Vitamin D levels, HbA1c and lipid profile in newly arrived Eritrean refugees in Switzerland. Eur J Public Health, 2017;26(Suppl. 1):378

2017
Conference Paper

Labhardt N.D, Müller U.F, Ringera I, Ehmer J, Motlatsi M.M, Pfeiffer K, Hobbins M.A, Muhairwe J.A, Muser J, Hatz C. Metabolic syndrome in patients on first-line antiretroviral therapy containing zidovudine or tenofovir in rural Lesotho, Southern Africa. Trop Med Int Health. 2017;22(6):725-733. DOI: 10.1111/tmi.12872

2017
Journal Article
PubMed (28342180)

Labhardt N.D, Ringera I, Lejone T.I, Cheleboi M, Wagner S, Muhairwe J, Klimkait T. When patients fail UNAIDS' last 90-the "failure cascade" beyond 90-90-90 in rural Lesotho, Southern Africa: a prospective cohort study. J Int AIDS Soc. 2017;20(1):21803. DOI: 10.7448/IAS.20.1.21803

2017
Journal Article
PubMed (28777506)

Moser W, Labhardt N.D, Cheleboi M, Muhairwe J, Keiser J. Unexpected low soil-transmitted helminth prevalence in the Butha-Buthe district in Lesotho, results from a cross-sectional survey. Parasit Vectors. 2017;10(1):72. DOI: 10.1186/s13071-017-1995-x

2017
Journal Article
PubMed (28179008)
Link

Cerutti B, Bader J, Ehmer J, Pfeiffer K, Klimkait T, Labhardt N.D. Performance of risk-charts to guide targeted HIV viral load monitoring of ART: applying the method on the data from a multi-centre-study in rural Lesotho [Letter]. J Acquir Immune Defic Syndr. 2016;72(1):e22-e25. DOI: 10.1097/QAI.0000000000000961

2016
Journal Item
PubMed (26910500)

Cerutti B, Broers B, Masetsibi M, Faturiyele O, Toti-Mokoteli L, Motlatsi M, Bader J, Klimkait T, Labhardt N.D. Alcohol use and depression: link with adherence and viral suppression in adult patients on antiretroviral therapy in rural Lesotho, Southern Africa: a cross-sectional study. BMC Public Health. 2016;16:947. DOI: 10.1186/s12889-016-3209-4

2016
Journal Article
PubMed (27608764)
Link

Halter Georg, Heuss Christian. Kampf gegen Aids in Lesotho [TV Broadcast]. Zürich: SRF Schweizer Radio und Fernsehen. SRF Schweizer Radio und Fernsehen, Bericht: Georg Halter. Bilder: Christian Heuss. Tagesschau vom 1. Dezember 2016

2016
Film or Broadcast
Link