Alvar J, Alves F, Bucheton B, Burrows L, Buscher P, Carrillo E, Felger I, Hubner M.P, Moreno J, Pinazo M.J, Ribeiro I, Sosa-Estani S, Specht S, Tarral A, Wourgaft N.S, Bilbe G. Implications of asymptomatic infection for the natural history of selected parasitic tropical diseases. Semin Immunopathol. 2020;42(3):231-246. DOI: 10.1007/s00281-020-00796-y

2020
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PubMed (32189034)

Eldh M, Hammar U, Arnot D, Beck H.P, Garcia A, Liljander A, Mercereau-Puijalon O, Migot-Nabias F, Mueller I, Ntoumi F, Ross A, Smith T, Sonden K, Homann M.V, Yman V, Felger I, Farnert A. Multiplicity of asymptomatic Plasmodium falciparum infections and risk of clinical malaria: a systematic review and pooled analysis of individual participant data. J Infect Dis. 2020;221(5):775-785. DOI: 10.1093/infdis/jiz510

2020
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PubMed (31585009)

Felger I, Snounou G, Hastings I, Moehrle J.J, Beck H.P. PCR correction strategies for malaria drug trials: updates and clarifications. Lancet Infect Dis. 2020;20(1):e20-e25. DOI: 10.1016/S1473-3099(19)30426-8

2020
Journal Article
PubMed (31540841)

Grossenbacher B, Holzschuh A, Hofmann N.E, Omar K.A, Stuck L, Fakih B.S, Ali A, Yukich J, Hetzel M.W, Felger I. Molecular methods for tracking residual Plasmodium falciparum transmission in a close-to-elimination setting in Zanzibar. Malar J. 2020;19:50. DOI: 10.1186/s12936-020-3127-x

2020
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PubMed (31996210)
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Grünberg M, Antunes Moniz C.A, Hofmann N.E, Koepfli C, Robinson L.J, Nate E, Monteiro W.M, de Melo G.C, Kuehn A, Siqueira A.M, Nguitragool W, Bassat Q, Lacerda M, Sattabongkot J, Mueller I, Felger I. Utility of ultra-sensitive qPCR to detect Plasmodium falciparum and Plasmodium vivax infections under different transmission intensities. Malar J. 2020;19:319. DOI: 10.1186/s12936-020-03374-7

2020
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PubMed (32883308)
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Grünberg M, Hofmann N.E, Nate E, Karl S, Robinson L.J, Lanke K, Smith T.A, Bousema T, Felger I. qRT-PCR versus IFA-based quantification of male and female gametocytes in low-density Plasmodium falciparum infections and their relevance for transmission. J Infect Dis. 2020;221(4):598-607. DOI: 10.1093/infdis/jiz420

2020
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PubMed (31437280)
Link

Hartley M.A, Hofmann N, Keitel K, Kagoro F, Antunes Moniz C, Mlaganile T, Samaka J, Masimba J, Said Z, Temba H, Gonzalez I, Felger I, Genton B, D'Acremont V. Clinical relevance of low-density Plasmodium falciparum parasitemia in untreated febrile children: a cohort study. PLoS Med. 2020;17(9):e1003318. DOI: 10.1371/journal.pmed.1003318

2020
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PubMed (32956354)
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Kattenberg J.H, Gumal D.L, Ome-Kaius M, Kiniboro B, Philip M, Jally S, Kasian B, Sambale N, Siba P.M, Karl S, Barry A.E, Felger I, Kazura J.W, Mueller I, Robinson L.J. The epidemiology of Plasmodium falciparum and Plasmodium vivax in East Sepik Province, Papua New Guinea, pre- and post-implementation of national malaria control efforts. Malar J. 2020;19:198. DOI: 10.1186/s12936-020-03265-x

2020
Journal Article
PubMed (32503607)
Link

Kattenberg J.H, Razook Z, Keo R, Koepfli C, Jennison C, Lautu-Gumal D, Fola A.A, Ome-Kaius M, Barnadas C, Siba P, Felger I, Kazura J, Mueller I, Robinson L.J, Barry A.E. Monitoring Plasmodium falciparum and Plasmodium vivax using microsatellite markers indicates limited changes in population structure after substantial transmission decline in Papua New Guinea. Mol Ecol. 2020(in press). DOI: 10.1111/mec.15654

2020
Journal Article
PubMed (32985031)

Moreira J, Barros J, Lapouble O, Lacerda M.V.G, Felger I, Brasil P, Dittrich S, Siqueira A.M. When fever is not malaria in Latin America: a systematic review. BMC Med. 2020;18:294. DOI: 10.1186/s12916-020-01746-z

2020
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PubMed (32951589)
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Stuck L, Fakih B.S, Al-Mafazy A.H, Hofmann N.E, Holzschuh A, Grossenbacher B, Bennett A, Cotter C, Reaves E, Ali A, der Horst T.V, Felger I, Hetzel M.W, Yukich J. Malaria infection prevalence and sensitivity of reactive case detection in Zanzibar. Int J Infect Dis. 2020;97:337-346. DOI: 10.1016/j.ijid.2020.06.017

2020
Journal Article
PubMed (32534138)
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Grünberg M, Lerch A, Beck H.P, Felger I. Amplicon deep sequencing improves Plasmodium falciparum genotyping in clinical trials of antimalarial drugs. Sci Rep. 2019;9:17790. DOI: 10.1038/s41598-019-54203-0

2019
Journal Article
PubMed (31780741)
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Hofmann N.E, Antunes Moniz C, Holzschuh A, Keitel K, Boillat-Blanco N, Kagoro F, Samaka J, Mbarack Z, Ding X.C, Gonzalez I.J, Genton B, D'Acremont V, Felger I. Diagnostic performance of conventional and ultrasensitive rapid diagnostic tests for malaria in febrile outpatients in Tanzania. J Infect Dis. 2019;219(9):1490-1498. DOI: 10.1093/infdis/jiy676

2019
Journal Article
PubMed (30476111)
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Jones S, Kay K, Hodel E.M, Chy S, Mbituyumuremyi A, Uwimana A, Menard D, Felger I, Hastings I. Improving methods for analysing anti-malarial drug efficacy trials: molecular correction based on length-polymorphic markers msp-1, msp-2 and glurp. Antimicrob Agents Chemother. 2019;63(9):e00590-19. DOI: 10.1128/AAC.00590-19

2019
Journal Article
PubMed (31307982)

Lerch A, Koepfli C, Hofmann N.E, Kattenberg J.H, Rosanas-Urgell A, Betuela I, Mueller I, Felger I. Longitudinal tracking and quantification of individual Plasmodium falciparum clones in complex infections. Sci Rep. 2019;9:3333. DOI: 10.1038/s41598-019-39656-7

2019
Journal Article
PubMed (30833657)
Link

Nguitragool W, Karl S, White M, Koepfli C, Felger I, Singhasivanon P, Müller I, Sattabongkot J. Highly heterogeneous residual malaria risk in western Thailand. Int J Parasitol. 2019;49(6):455-462. DOI: 10.1016/j.ijpara.2019.01.004

2019
Journal Article
PubMed (30954453)

Ome-Kaius M, Kattenberg J.H, Zaloumis S, Siba M, Kiniboro B, Jally S, Razook Z, Mantila D, Sui D, Ginny J, Rosanas-Urgell A, Karl S, Obadia T, Barry A, Rogerson S.J, Laman M, Tisch D, Felger I, Kazura J.W, Mueller I, Robinson L.J. Differential impact of malaria control interventions on P. falciparum and P. vivax infections in young Papua New Guinean children. BMC Med. 2019;17:220. DOI: 10.1186/s12916-019-1456-9

2019
Journal Article
PubMed (31813381)
Link

Slater H.C, Ross A, Felger I, Hofmann N.E, Robinson L, Cook J, Goncalves B.P, Björkman A, Ouedraogo A.L, Morris U, Msellem M, Koepfli C, Mueller I, Tadesse F, Gadisa E, Das S, Domingo G, Kapulu M, Midega J, Owusu-Agyei S, Nabet C, Piarroux R, Doumbo O, Doumbo S.N, Koram K, Lucchi N, Udhayakumar V, Mosha J, Tiono A, Chandramohan D, Gosling R, Mwingira F, Sauerwein R, Riley E.M, White N.J, Nosten F, Imwong M, Bousema T, Drakeley C, Okell L.C. The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density. Nat Commun. 2019;10:1433. DOI: 10.1038/s41467-019-09441-1

2019
Journal Article
PubMed (30926893)
Link

Slater H.C, Ross A, Felger I, Hofmann N.E, Robinson L, Cook J, Goncalves B.P, Bjorkman A, Ouedraogo A.L, Morris U, Msellem M, Koepfli C, Mueller I, Tadesse F, Gadisa E, Das S, Domingo G, Kapulu M, Midega J, Owusu-Agyei S, Nabet C, Piarroux R, Doumbo O, Doumbo S.N, Koram K, Lucchi N, Udhayakumar V, Mosha J, Tiono A, Chandramohan D, Gosling R, Mwingira F, Sauerwein R, Paul R, Riley E.M, White N.J, Nosten F, Imwong M, Bousema T, Drakeley C, Okell L.C. Author correction: The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density. Nat Commun. 2019;10(1):2644. DOI: 10.1038/s41467-019-10790-0

2019
Journal Item
PubMed (31186429)
Link

Steiner-Monard V, Kamaka K, Karoui O, Roethlisberger S, Audran R, Daubenberger C, Fayet-Mello A, Erdmann-Voisin A, Felger I, Geiger K, Govender L, Houard S, Huber E, Mayor C, Mkindi C, Portevin D, Rusch S, Schmidlin S, Tiendrebeogo R.W, Theisen M, Thierry A.C, Vallotton L, Corradin G, Leroy O, Abdulla S, Shekalaghe S, Genton B, Spertini F, Jongo S.A. The candidate blood-stage malaria vaccine P27A induces a robust humoral response in a fast track to the field phase I trial in exposed and non exposed volunteers. Clin Infect Dis. 2019;68(3):466-474. DOI: 10.1093/cid/ciy514

2019
Journal Article
PubMed (29945169)

Yorsaeng R, Saesue T, Chotivanich K, Felger I, Wampfler R, Cui L, Mueller I, Sattabongkot J, Nguitragool W. Indigenous Plasmodium malariae infection in an endemic population at the Thai-Myanmar border. Am J Trop Med Hyg. 2019;100(5):1164-1169. DOI: 10.4269/ajtmh.18-0597

2019
Journal Article
PubMed (30793693)

Almeida A.C.G, Kühn A, Castro A.J.M, Vitor-Silva S, Figueiredo E.F.G, Brasil L.W, Brito M.A.M, Sampaio V.S, Bassat Q, Felger I, Tadei W.P, Monteiro W.M, Mueller I, Lacerda M.V.G. High proportions of asymptomatic and submicroscopic Plasmodium vivax infections in a peri-urban area of low transmission in the Brazilian Amazon. Parasit Vectors. 2018;11:194. DOI: 10.1186/s13071-018-2787-7

2018
Journal Article
PubMed (29558985)
Link

Grünberg M, Antunes Moniz C, Hofmann N.E, Wampfler R, Köpfli C, Mueller I, Monteiro W.M, Lacerda M, de Melo G.C, Kuehn A, Siqueira A.M, Felger I. Plasmodium vivax molecular diagnostics in community surveys: pitfalls and solutions. Malar J. 2018;17:55. DOI: 10.1186/s12936-018-2201-0

2018
Journal Article
PubMed (29378609)
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Hofmann N.E, Grünberg M, Nate E, Ura A, Rodriguez-Rodriguez D, Salib M, Mueller I, Smith T.A, Laman M, Robinson L.J, Felger I. Assessment of ultra-sensitive malaria diagnosis versus standard molecular diagnostics for malaria elimination: an in-depth molecular community cross-sectional study. Lancet Infect Dis. 2018;18(10):1108-1116. DOI: 10.1016/S1473-3099(18)30411-0

2018
Journal Article
PubMed (30170986)

Meerstein-Kessel L, Andolina C, Carrió E, Mahamar A, Sawa P, Diawara H, van de Vegte-Bolmer M, Stone W, Collins K.A, Schneider P, Dicko A, Drakeley C, Felger I, Voss T, Lanke K, Bousema T. A multiplex assay for the sensitive detection and quantification of male and female Plasmodium falciparum gametocytes. Malar J. 2018;17:441. DOI: 10.1186/s12936-018-2584-y

2018
Journal Article
PubMed (30497508)
Link

Rodrigues P.T, Valdivia H.O, de Oliveira T.C, Alves J.M.P, Duarte A.M.R.C, Cerutti-Junior C, Buery J.C, Brito C.F.A, de Souza J.C.Jr, Hirano Z.M.B, Bueno M.G, Catao-Dias J.L, Malafronte R.S, Ladeia-Andrade S, Mita T, Santamaria A.M, Calzada J.E, Tantular I.S, Kawamoto F, Raijmakers L.R.J, Mueller I, Pacheco M.A, Escalante A.A, Felger I, Ferreira M.U. Human migration and the spread of malaria parasites to the New World. Sci Rep. 2018;8(1):1993. DOI: 10.1038/s41598-018-19554-0

2018
Journal Article
PubMed (29386521)
Link

White M.T, Karl S, Koepfli C, Longley R.J, Hofmann N.E, Wampfler R, Felger I, Smith T, Nguitragool W, Sattabongkot J, Robinson L, Ghani A, Mueller I. Plasmodium vivax and Plasmodium falciparum infection dynamics: re-infections, recrudescences and relapses. Malar J. 2018;17:170. DOI: 10.1186/s12936-018-2318-1

2018
Journal Article
PubMed (29665803)
Link

Bachmann L, Felger I, Haring E, Maier D, Pinsker W, Preiss A. In memoriam Prof. Dr. Dr. h. c. Diether Sperlich (1929 - 2017). J Zool Syst Evol Res. 2017;55(4):267-268. DOI: 10.1111/jzs.12181

2017
Journal Item

Céspedes N, Li Wai Suen C.S.N, Koepfli C, Franca C.T, Felger I, Nebie I, Arevalo-Herrera M, Mueller I, Corradin G, Herrera S. Natural immune response to Plasmodium vivax alpha-helical coiled coil protein motifs and its association with the risk of P. vivax malaria. PLoS One. 2017;12(6):e0179863. DOI: 10.1371/journal.pone.0179863

2017
Journal Article
PubMed (28651021)
Link

Ding X.C, Ade M.P, Baird J.K, Cheng Q, Cunningham J, Dhorda M, Drakeley C, Felger I, Gamboa D, Harbers M, Herrera S, Lucchi N, Mayor A, Mueller I, Sattabongkot J, Ratsimbason A, Richards J, Tanner M, Gonzalez I.J. Defining the next generation of Plasmodium vivax diagnostic tests for control and elimination: target product profiles. PLoS Negl Trop Dis. 2017;11(4):e0005516. DOI: 10.1371/journal.pntd.0005516

2017
Journal Article
PubMed (28369085)
Link

Hofmann N.E, Karl S, Wampfler R, Kiniboro B, Teliki A, Iga J, Waltmann A, Betuela I, Felger I, Robinson L.J, Mueller I. The complex relationship of exposure to new Plasmodium infections and incidence of clinical malaria in Papua New Guinea. Elife. 2017;6:e23708. DOI: 10.7554/eLife.23708

2017
Journal Article
PubMed (28862132)

Lerch A, Köpfli C, Hofmann N.E, Messerli C, Wilcox S, Kattenberg J.H, Betuela I, O'Connor L, Mueller I, Felger I. Development of amplicon deep sequencing markers and data analysis pipeline for genotyping multi-clonal malaria infections. BMC Genomics. 2017;18:864. DOI: 10.1186/s12864-017-4260-y

2017
Journal Article
PubMed (29132317)
Link

Letang E, Verdastus Kalinjuma A, Glass T.R, Gamell A, Mapesi H, Sikalengo G.R, Luwanda L.B, Mnzava D, Ntamatungiro A.J, Ndaki R, Francis G, Vanobbergen F, Furrer H, Klimkait T, Felger I, Tanner M, Hatz C, Weisser M, Battegay M, KIULARCO Study Group. Cohort profile: the Kilombero and Ulanga Antiretroviral Cohort (KIULARCO): a prospective HIV cohort in rural Tanzania. Swiss Med Wkly. 2017;147:w14485. DOI: 10.4414/smw.2017.14485

2017
Journal Article
PubMed (28695551)
Link

Messerli C, Hofmann N.E, Beck H.P, Felger I. Critical evaluation of molecular monitoring in malaria drug efficacy trials and pitfalls of length-polymorphic markers. Antimicrob Agents Chemother. 2017;61(1):e01500-16. DOI: 10.1128/AAC.01500-16

2017
Journal Article
PubMed (27821442)

Muri L, Gamell A, Ntamatungiro A.J, Glass T.R, Luwanda L.B, Battegay M, Furrer H, Hatz C, Tanner M, Felger I, Klimkait T, Letang E, Kiularco Study Group. Development of HIV drug resistance and therapeutic failure in children and adolescents in rural Tanzania - an emerging public health concern. AIDS. 2017;31(1):61-70. DOI: 10.1097/QAD.0000000000001273

2017
Journal Article
PubMed (27677163)
Link

Nguitragool W, Mueller I, Kumpitak C, Saeseu T, Bantuchai S, Yorsaeng R, Yimsamran S, Maneeboonyang W, Sa-Angchai P, Chaimungkun W, Rukmanee P, Puangsa-Art S, Thanyavanich N, Koepfli C, Felger I, Sattabongkot J, Singhasivanon P. Very high carriage of gametocytes in asymptomatic low-density Plasmodium falciparum and P. vivax infections in western Thailand. Parasit Vectors. 2017;10:512. DOI: 10.1186/s13071-017-2407-y

2017
Journal Article
PubMed (29065910)
Link

Ntamatungiro A.J, Muri L, Glass T.R, Erb S, Battegay M, Furrer H, Hatz C, Tanner M, Felger I, Klimkait T, Letang E, Kiularco Study Group. Strengthening HIV therapy and care in rural Tanzania affects rates of viral suppression. J Antimicrob Chemother. 2017;72(7):2069-2074. DOI: 10.1093/jac/dkx095

2017
Journal Article
PubMed (28387865)

Siqueira A.M, Alencar A.C, Melo G.C, Magalhaes B.L, Machado K, Alencar Filho A.C, Kuehn A, Marques M.M, Manso M.C, Felger I, Vieira J.L, Lameyre V, Daniel-Ribeiro C.T, Lacerda M.V. Fixed-dose artesunate-amodiaquine combination vs chloroquine for treatment of uncomplicated blood stage P. vivax infection in the Brazilian Amazon: an open-label randomized, controlled trial. Clin Infect Dis. 2017;64(2):166-174. DOI: 10.1093/cid/ciw706

2017
Journal Article
PubMed (27988484)

Tadesse F.G, van den Hoogen L, Lanke K, Schildkraut J, Tetteh K, Aseffa A, Mamo H, Sauerwein R, Felger I, Drakeley C, Gadissa E, Bousema T. The shape of the iceberg: quantification of submicroscopic Plasmodium falciparum and Plasmodium vivax parasitaemia and gametocytaemia in five low endemic settings in Ethiopia. Malar J. 2017;16:99. DOI: 10.1186/s12936-017-1749-4

2017
Journal Article
PubMed (28253867)
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The malERA Refresh Consultative Panel on Characterising the Reservoir and Measuring Transmission. malERA: an updated research agenda for characterising the reservoir and measuring transmission in malaria elimination and eradication. PLoS Med. 2017;14(11):e1002452. DOI: 10.1371/journal.pmed.1002452

2017
Journal Article
PubMed (29190279)
Link