Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid <em>Trypanosoma brucei</em> (Publications)
A whole-organism screen of approximately 87000 compounds against Trypanosoma brucei brucei identified a number of promising compounds for medicinal chemistry optimization. One of these classes of comp
Heterochromatin protein 1 secures survival and transmission of malaria parasites (Publications)
Clonally variant expression of surface antigens allows the malaria parasite Plasmodium falciparum to evade immune recognition during blood stage infection and secure malaria transmission. We demonstra
Histopathological changes in juvenile <em>Schistosoma haematobium</em> harboured in hamsters treated with artemether (Publications)
Histopathological changes in juvenile Schistosoma haematobium, caused by artemether administered to the infected hamsters, were studied. Hamsters were infected with S. haematobium cercariae, and after
A model of animal-human brucellosis transmission in Mongolia (Publications)
We developed a dynamic model of livestock-to-human brucellosis transmission in Mongolia. The compartmental model considers transmission within sheep and cattle populations and the transmission to huma
The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Côte d'Ivoire (Publications)
BACKGROUND: Iron is essential for the growth and virulence of many pathogenic enterobacteria, whereas beneficial barrier bacteria, such as lactobacilli, do not require iron. Thus, increasing colonic i
Rice irrigation and schistosomiasis in savannah and forest areas of Côte d'Ivoire (Publications)
Prevalence and intensity of infection of Schistosoma haematobium and Schistosoma mansoni were studied in relation to irrigated rice cultivation in Cote d'Ivoire. Urine and stool samples were collected
Tegumental changes in 21-day-old <em>Schistosoma mansoni</em> harboured in mice treated with artemether (Publications)
Alterations in the tegument of 21-day-old Schistosoma mansoni, caused by artemether administered to the infected mice, were studied using scanning electron microscopy (SEM). Mice were infected with S.