Development of behaviour change communication strategy for a vaccination-linked malaria control tool in southern Tanzania (Publications)
preventive treatment of malaria in infants (IPTi) using sulphadoxine-pyrimethamine and linked to the expanded programme on immunization (EPI) is a promising strategy for malaria control in young children [...] after the injections. Sulphadoxine-pyrimethamine was widely used for malaria treatment and intermittent preventive treatment of malaria in pregnancy, despite widespread rumours of adverse reactions based [...] survey were used to investigate communities' and providers' knowledge and...
Frequency of malaria and glucose-6-phosphate dehydrogenase deficiency in Tajikistan (Publications)
high malaria risk with high current incidence rates, where malaria control and prevention measures should be taken at all stages of the transmission cycle; (ii) zones at relatively high malaria risk with [...] with low current incidence rates, where malaria prevention measures are recommended; and (iii) zones at intermediate or low malaria risk with low current incidence rates where no particular measures appear [...] indicates that malaria is a serious health issue in specific regions of...
Genetic diversity of expressed <em>Plasmodium falciparum</em> var genes from Tanzanian children with severe malaria (Publications)
BACKGROUND: Severe malaria has been attributed to the expression of a restricted subset of the var multigene family, which encodes for Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). PfEMP1 [...] in Tanzanian children was analysed. METHODS: Children with defined severe (SM) and asymptomatic malaria (AM) were recruited. Fulllength var mRNA was isolated and reversed transcribed into var cDNA. Su
What should vaccine developers ask? Simulation of the effectiveness of malaria vaccines (Publications)
effects of malaria vaccines on malaria transmission, morbidity and mortality. The models are fitted and simulations obtained via volunteer computing. We consider a range of endemic malaria settings with [...] BACKGROUND: A number of different malaria vaccine candidates are currently in pre-clinical or clinical development. Even though they vary greatly in their characteristics, it is unlikely that any of them [...] them will provide long-lasting sterilizing immunity against the malaria parasite....
Malaria: a major health problem within an oil palm plantation around Popondetta, Papua New Guinea (Publications)
023 malaria cases were diagnosed at the aid posts and malaria accounted for 30-40% of all clinical cases. Of the malaria cases, 13-20% were HOP employees. On average, an employee sick with malaria was [...] BACKGROUND: For companies operating in malaria endemic countries, malaria represents a substantial risk to workers and their dependants, and can lead to significantly reduced worker productivity. This [...] 2006. Sleeping outside of the house did not increase the risk of a malaria infection,...
Malaria transmission after five years of vector control on Bioko Island, Equatorial Guinea (Publications)
ABSTRACT: BACKGROUND: Malaria is endemic with year-round transmission on Bioko Island. The Bioko Island Malaria Control Project (BIMCP) started in 2004 with the aim to reduce malaria transmission and to [...] to ultimately eliminate malaria. While the project has been successful in reducing overall malaria morbidity and mortality, foci of high malaria transmission still persist on the island. Results from the
Implementation of an insecticide-treated net subsidy scheme under a public-private partnership for malaria control in Tanzania--challenges in... (Publications)
commitments from organizations such as the Global Fund for HIV/AIDS, Tuberculosis and Malaria (GFATM), the President's Malaria Initiative and the World Bank Booster programme. METHODS: The case study uses the [...] BACKGROUND: In the past decade there has been increasing visibility of malaria control efforts at the national and international levels. The factors that have enhanced this scenario are the availability [...] implementation of a public-private partnership approach embarked upon by the...
Ecologists can enable communities to implement malaria vector control in Africa (Publications)
BACKGROUND: Integrated vector management (IVM) for malaria control requires ecological skills that are very scarce and rarely applied in Africa today. Partnerships between communities and academic ecologists [...] programme at grassroots level, which was subsequently upgraded and expanded into a pilot scale Urban Malaria Control Programme with support from national academic institutes. RESULTS: Both programmes now access [...] ed implementation and operational research opportunities. The...
Three different <em>Plasmodium</em> species show similar patterns of clinical tolerance of malaria infection (Publications)
data on the age dependence of tolerance in other species of human malaria. METHODS: Parasite densities measured in 24,386 presumptive malaria cases at two local health centres in the Wosera area of Papua New [...] BACKGROUND: In areas where malaria endemicity is high, many people harbour blood stage parasites without acute febrile illness, complicating the estimation of disease burden from infection data. For Plasmodium [...] acute illness is approximately proportion to the logarithm of the...