State of inequality in malaria intervention coverage in sub-Saharan African countries (Publications)
BACKGROUND: Scale-up of malaria interventions over the last decade have yielded a significant reduction in malaria transmission and disease burden in sub-Saharan Africa. We estimated economic gradients [...] in coverage of malaria interventions and their distribution by wealth within and across countries. In most, economic gradients are lacking or favor the poorest for vector control; malaria services delivered [...] Using Demographic and Health Surveys we computed equity metrics to characterize...
The interspecific competition between larvae of <em>Aedes aegypti</em> and major african malaria vectors in a semi-field system in Tanzania (Publications)
Interspecific competition between mosquito larvae may affects adult vectorial capacity, potentially reducing disease transmission. It also influences population dynamics, and cannibalistic and predato
Contrasting vector competence of three main East African <em>Anopheles</em> malaria vector mosquitoes for <em>Plasmodium falciparum</em> (Publications)
three malaria vector species may contribute to malaria transmission in East Africa, with An. funestus demonstrating superior vector competence. In conclusion, there is a need for comprehensive malaria control [...] control strategies targeting major malaria vector species, an update of malaria transmission models to consider vector competence and evaluation of malaria transmission blocking interventions in assays that [...] majority of malaria transmission, posing a significant public health...
Comparison of fine-scale malaria strata derived from population survey data collected using RDTs, microscopy and qPCR in south-eastern Tanzania (Publications)
BACKGROUND: Malaria-endemic countries are increasingly adopting data-driven risk stratification, often at district or higher regional levels, to guide their intervention strategies. The data typically
Therapeutic development to accelerate malaria control through intentional intervention layering (Publications)
significant advancements in the prevention of Plasmodium falciparum malaria. These innovations could support regions in accelerating malaria control, transforming existing intervention packages by supplementing [...] studies of new medical products, sufficiently capture the broader goal of accelerating malaria control? Layering novel malaria products requires monitoring health outcomes that reflect the novel product's targeted [...] offering an entirely new tool. However, to layer new medical...
A combined school survey and reactive case detection reveals minimal local transmission of malaria in the Highlands Region of Papua New Guinea (Publications)
Highlands of Papua New Guinea are non-endemic for malaria compared to the rest of the country. This study aimed to explore the local transmission of malaria in the Highlands through a cross-sectional school [...] 1048 household members were screened for malaria using Rapid Diagnostic Tests, subsequently validated by light microscopy. In addition, an analysis of malaria cases (2017 to 2019) was conducted across [...] Local malaria transmission appears to be minimal in the surveyed Highlands...
A matter of timing: biting by malaria-infected <em>Anopheles</em> mosquitoes and the use of interventions during the night in rural south-eastern... (Publications)
Knowing when and where infected mosquitoes bite is required for estimating accurate measures of malaria risk, assessing outdoor exposure, and designing intervention strategies. This study combines secondary [...] behaviour survey and an entomological survey carried out in the same area to estimate human exposure to malaria-infected Anopheles mosquitoes throughout the night in rural villages in south-eastern Tanzania. [...] Individuals were mainly outdoors before 9PM, and mainly indoors between...
Insights into the biology and insecticide susceptibility of the secondary malaria vector <em>Anopheles parensis</em> in an area with long-term use of... (Publications)
at least 11 sibling species, with Anopheles funestus Giles being the most studied and significant malaria vector. Other species, like Anopheles parensis, are understudied despite their potential role in [...] lity of An. parensis. Primarily feeding on non-human hosts, An. parensis is less significant in malaria transmission than more anthropophilic vectors. Unlike the pyrethroid-resistant An. funestus sensu [...] findings provide a foundation for future research and may inform control strategies...