Structural and functional characterisation of the toll like receptor 9 of <em>Aotus nancymaae</em>, a non-human primate model for malaria vaccine... (Publications)
In the absence of suitable rodent animal models for Plasmodium falciparum malaria, the efficacy testing of asexual blood-stage vaccine candidates in Aotus nancymaae represents a tool to select between [...] sequence conservation of Aona-TLR-9 reinforces the suitability of A. nancymaae as animal model for malaria subunit vaccine development
The changing epidemiology of malaria in Ifakara Town, southern Tanzania (Publications)
Between 1995 and 2000 there were marked changes in the epidemiology of malaria in Ifakara, southern Tanzania. We documented these changes using parasitological and clinical data from a series of community- [...] age-specific parasite prevalence in the community-based cohort studies. The incidence of clinical malaria in placebo-receiving infants in additional study cohorts dropped from 0.8 in 1995 to 0.43 episodes
Effectiveness of artemether/lumefantrine for the treatment of uncomplicated <em>Plasmodium vivax</em> and <em>P. falciparum</em> malaria in young... (Publications)
uncomplicated Plasmodium falciparum (Pf) malaria, while chloroquine is still widely used for non-Pf infections. A common treatment for both vivax and falciparum malaria would be welcome.Methods. A longitudinal [...] had an infection confirmed by blood slide (BS) examination. Of these, 594 Pv and 332 Pf clinical malaria cases were included in the primary effectiveness analysis. Clinical treatment failure rates at 7 [...] 7, 28 and 42 days were 0.2%, 2.2% and 12.0% for Pv and 0.3%, 1.2% and 3.6%...
The economic cost to households of childhood malaria in Papua New Guinea: a focus on intra-country variation (Publications)
BACKGROUND We compare direct and indirect household costs associated with malaria treatment for children
