Natural variation in timing of egg hatching, response to water agitation, and bidirectional selection of early and late hatching strains of the... (Publications)
variation in egg hatching and its environmental and genetic determinants in sibling species of the malaria vector Anopheles gambiae s.l. is important for understanding their adaptation to variable aquatic
Scalable camera traps for measuring the attractiveness of sugar baits for controlling malaria and dengue vectors (Publications)
BACKGROUND: Attractive targeted sugar baits (ATSBs) are promising new interventions that can complement existing vector control tools. However, reproducible and quantitative information on the level o
Impact of climate variability and interventions on malaria incidence and forecasting in Burkina Faso (Publications)
BACKGROUND: Malaria remains a climate-driven public health issue in Burkina Faso, yet the interactions between climatic factors and malaria interventions across different zones are not well understood [...] suitability and malaria incidence. Wavelet analysis was conducted to understand better how fluctuations in climatic factors across different time scales and climatic zones affect malaria transmission dynamics [...] . This study estimates time delays in the effects of climatic factors on malar...
Slow clearance of histidine-rich protein-2 in Gabonese with uncomplicated malaria (Publications)
Malaria rapid diagnostic tests (RDTs), which detect Plasmodium falciparum (Pf)-specific histidine-rich protein-2 (HRP2), have increasing importance for the diagnosis and control of malaria, especially [...] RDT-based assessment following a malaria treatment for weeks. A better understanding of the HRP2 clearance dynamics is critical for guiding the diagnosis of malaria when relying on RDTs. IMPORTANCE: Detecting [...] determine the long-term kinetic of HRP2-levels in peripheral blood after...
The impact of soil transmitted helminth on malaria clinical presentation and treatment outcome: a case control study among children in Bagamoyo... (Publications)
been documented between Plasmodium and STH. This study investigated the impact of STH on clinical malaria presentation and treatment outcome. METHODS: A matched case control study with a semi longitudinal [...] areas of Bagamoyo, coastal region of Tanzania. Cases were children with uncomplicated and severe malaria enrolled from the health facilities while controls were children with asymptomatic Plasmodium parasitemia [...] regression analysis there was a tendency for a protective effect of STH...
Embedded-deep-learning-based sample-to-answer device for on-site malaria diagnosis (Publications)
digital image transmission. This method can set a new paradigm for on-site malaria diagnosis. The miLabâ„¢ algorithm for malaria detection achieved a total accuracy of 98.86% for infected red blood cell (RBC) [...] Improvements in digital microscopy are critical for the development of a malaria diagnosis method that is accurate at the cellular level and exhibits satisfactory clinical performance. Digital microscopy [...] 92.21%. Based on these results, miLabâ„¢ can become a reliable and efficient...
Travel to malaria-endemic areas: using digital geo-location to assess potential exposure risks and health behaviours (Publications)
and Tanzania, each presenting varying malaria risks. The extent to which travellers enter high-risk malaria-endemic areas in destinations with heterogeneous malaria risk remains unclear. We used geo-location [...] heterogeneous malaria risk (Brazil, India, Peru, Thailand), and (ii) compare mosquito bite prevention behaviours between these destinations and Tanzania, considered entirely high-risk for malaria. METHODS: [...] health and geo-location data were collected using a smartphone...