MATIAS (Page)
https://www.swisstph.ch/fr/about/med/medicines-implementation-research/matias
for treatment of severe malaria caused by Plasmodium falciparum . These results with high quality evidence led to a change in the WHO guidelines for the treatment of severe malaria in children and adults [...] Key Project | MATIAS Treatment of Severe Malaria with Injectable Artesunate Implementation Non-Controlled Longitudinal Observational Study to Support Artesunate Introduction in the Democratic Republic [...] the Congo (DRC) In 2010, the AQUAMAT study demonstrated that, in children, the...
Vaccine potentials of an intrinsically unstructured fragment derived from the blood stage-associated <em>Plasmodium falciparum</em> protein PFF0165c (Publications)
with its low polymorphism and association with clinical protection from malaria in humans, warrant its further development as a malaria vaccine candidate [...] We have identified new malaria vaccine candidates through the combination of bioinformatics prediction of stable protein domains in the Plasmodium falciparum genome, chemical synthesis of polypeptides [...] assays, and association of an antigen-specific antibody response with protection against clinical malaria. Within the predicted open...
Vaccine potentials of an intrinsically unstructured fragment derived from the blood stage-associated <em>Plasmodium falciparum</em> protein PFF0165c (Publications)
with its low polymorphism and association with clinical protection from malaria in humans, warrant its further development as a malaria vaccine candidate [...] We have identified new malaria vaccine candidates through the combination of bioinformatics prediction of stable protein domains in the Plasmodium falciparum genome, chemical synthesis of polypeptides [...] assays, and association of an antigen-specific antibody response with protection against clinical malaria. Within the predicted open...
Increased levels of anti-PfCSP antibodies in post-pubertal females versus males immunized with PfSPZ Vaccine does not translate into increased... (Publications)
shown differences in the risk of malaria infection and sickness between males and females, little is known about sex differences in vaccine-induced immunity to malaria. Identifying such differences could [...] could elucidate important aspects of malaria biology and facilitate development of improved approaches to malaria vaccination. METHODS: Using a standardized enzyme-linked immunosorbent assay, IgG antibodies [...] were associated with differential protection against naturally transmitted Pf...
Use of insecticides in agriculture and the prevention of vector-borne diseases: population knowledge, attitudes, practices and beliefs in Elibou,... (Publications)
and beliefs (KAPB) pertaining to malaria are generally well described. However, little is known about population knowledge and awareness of insecticide resistance in malaria vectors. The aim of this study [...] resistance in malaria vectors, while people's knowledge about insecticide resistance was limited. There is a need to raise awareness in communities about the presence of resistance in malaria vectors and [...] study was to investigate KAPB related to insecticide resistance in malaria...
Reduction in the proportion of fevers associated with <em>Plasmodium falciparum</em> parasitaemia in Africa: a systematic review (Publications)
BACKGROUND: Malaria is almost invariably ranked as the leading cause of morbidity and mortality in Africa. There is growing evidence of a decline in malaria transmission, morbidity and mortality over the [...] presenting with a syndrome of 'presumptive malaria', 3) numerators (number of parasitologically confirmed cases) and denominators (total number of presumptive malaria cases) available, 4) good quality microscopy [...] However, there is still doubt whether this decline is reflected in a...
Increased levels of anti-PfCSP antibodies in post-pubertal females versus males immunized with PfSPZ Vaccine does not translate into increased... (Publications)
shown differences in the risk of malaria infection and sickness between males and females, little is known about sex differences in vaccine-induced immunity to malaria. Identifying such differences could [...] could elucidate important aspects of malaria biology and facilitate development of improved approaches to malaria vaccination. METHODS: Using a standardized enzyme-linked immunosorbent assay, IgG antibodies [...] were associated with differential protection against naturally transmitted Pf...
Reduction in the proportion of fevers associated with <em>Plasmodium falciparum</em> parasitaemia in Africa: a systematic review (Publications)
BACKGROUND: Malaria is almost invariably ranked as the leading cause of morbidity and mortality in Africa. There is growing evidence of a decline in malaria transmission, morbidity and mortality over the [...] presenting with a syndrome of 'presumptive malaria', 3) numerators (number of parasitologically confirmed cases) and denominators (total number of presumptive malaria cases) available, 4) good quality microscopy [...] However, there is still doubt whether this decline is reflected in a...
Use of insecticides in agriculture and the prevention of vector-borne diseases: population knowledge, attitudes, practices and beliefs in Elibou,... (Publications)
and beliefs (KAPB) pertaining to malaria are generally well described. However, little is known about population knowledge and awareness of insecticide resistance in malaria vectors. The aim of this study [...] resistance in malaria vectors, while people's knowledge about insecticide resistance was limited. There is a need to raise awareness in communities about the presence of resistance in malaria vectors and [...] study was to investigate KAPB related to insecticide resistance in malaria...
The empirical support for the radical cure strategy for eliminating <em>Plasmodium vivax</em> in China (Publications)
China is malaria-free, it is timely to consider how elimination of malaria was completed in People's Republic of China over the last 7 decades. Of the four widespread species of human malaria, Plasmodium [...] planning disease elimination in other malaria-endemic countries, with residual P. vivax malaria. METHODS: We collated data from both published and unpublished malaria parasite inoculation experiments conducted [...] (late spring) seasons had a pronounced effect on outbreaks during the mala...
