Recherche de malaria.

1. Diagnostic capacity and antimalarial availability in Papua New Guinea before the introduction of a revised national malaria treatment protocol (Publications)

   Diagnostic capacity and antimalarial availability in Papua New Guinea before the introduction of a revised national malaria treatment protocol

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2. Evaluation of the safety and immunogenicity of the RTS,S/AS01E malaria candidate vaccine when integrated in the expanded program of immunization (Publications)

   Evaluation of the safety and immunogenicity of the RTS,S/AS01E malaria candidate vaccine when integrated in the expanded program of immunization

   Pertinence:

   BACKGROUND: The RTS,S/AS01(E) malaria candidate vaccine is being developed for immunization of African infants through the Expanded Program of Immunization (EPI). METHODS: This phase 2, randomized, open [...] registration. ClinicalTrials.gov identifier: NCT00436007 . GlaxoSmithKline study ID number: 106369 (Malaria-050)

3. Epigenetic memory takes center stage in the survival strategy of malaria parasites (Publications)

   Epigenetic memory takes center stage in the survival strategy of malaria parasites

   Pertinence:

   Malaria parasites run through a complex life cycle in the vertebrate host and mosquito vector. This not only requires tightly controlled mechanisms to govern stage-specific gene expression but also ne [...] sexual conversion and discuss the relevance of this strategy for the survival and transmission of malaria parasites.

4. Malaria and soil-transmitted intestinal helminth co-infection and its effect on anemia: a meta-analysis (Publications)

   Malaria and soil-transmitted intestinal helminth co-infection and its effect on anemia: a meta-analysis

   Pertinence:

   effect of malaria and STH on anemia. A subgroup analysis showed a higher risk of malaria infection in the primigravidae (summary OR: 1.61; 95% CI: 1.3-1.99; I(2): 0%). In conclusion, the malaria-STH co-infection [...] evidence on the extent of malaria and soil-transmitted intestinal helminth (STH) co-infections in people living in endemic countries and to explore the effect of interactions between malaria and STHs on anemia [...] of the association between anemia and the combined malaria and STH...

5. The treatment of non-malaria febrile illness in Papua New Guinea: findings from cross sectional and longitudinal studies of health worker practice (Publications)

   The treatment of non-malaria febrile illness in Papua New Guinea: findings from cross sectional and longitudinal studies of health worker practice

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6. Targeting <em>Plasmodium</em> PI(4)K to eliminate malaria (Publications)

   Targeting <em>Plasmodium</em> PI(4)K to eliminate malaria

   Pertinence:

   Achieving the goal of malaria elimination will depend on targeting Plasmodium pathways essential across all life stages. Here we identify a lipid kinase, phosphatidylinositol-4-OH kinase (PI(4)K), as the [...] azines demonstrate potent preventive, therapeutic, and transmission-blocking activity in rodent malaria models, are active against blood-stage field isolates of the major human pathogens P. falciparum [...] to identify drugs with an ideal activity profile for the prevention, treatment and...

7. Costing and budgeting for malaria service delivery (Publications)

   Costing and budgeting for malaria service delivery

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8. A molecular marker of artemisinin-resistant <em>Plasmodium falciparum</em> malaria (Publications)

   A molecular marker of artemisinin-resistant <em>Plasmodium falciparum</em> malaria

   Pertinence:

   Plasmodium falciparum resistance to artemisinin derivatives in southeast Asia threatens malaria control and elimination activities worldwide. To monitor the spread of artemisinin resistance, a molecular

9. A qualitative study of how affected individuals or their caregivers respond to suspected malaria infection in rural Papua New Guinea (Publications)

   A qualitative study of how affected individuals or their caregivers respond to suspected malaria infection in rural Papua New Guinea

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10. Primaquine treatment for <em>Plasmodium vivax</em> - an essential tool for malaria control and elimination in Papua New Guinea (Publications)

    Primaquine treatment for <em>Plasmodium vivax</em> - an essential tool for malaria control and elimination in Papua New Guinea

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