Age as a risk factor for severe manifestations and fatal outcome of <em>falciparum</em> <em>malaria</em> in European patients: observations from... (Publications)
Previous studies have indicated that age is a risk factor for severe falciparum malaria in nonimmune patients. The objectives of this study were to reevaluate previous findings with a larger sample and [...] younger patients. Results of adjusted analyses indicated that the risks of death due to falciparum malaria, of experiencing cerebral or severe disease in general, and of hospitalization increased significantly [...] susceptible to cerebral complications than were men. Our study provides...
Synthesis and biological properties of a rhodacyanine derivative, Ssj-127, having high efficacy against malaria protozoa (Publications)
One of rhodacyanine derivatives, SSJ-127 (1), showed a complete cure of a mouse model infected with Plasmodium berghei by subcutaneous administration. The synthesis, in vitro activities against severa
An algorithm for the clinical differentiation of malaria and typhoid: a preliminary communication (Publications)
and malaria are most helpful in distinguishing the two diseases among Papua New Guinean highlanders. In a study of 35 patients with culture-positive typhoid and 49 with blood-slide-positive malaria (Group [...] evaluated in a further group of 34 typhoid patients and 41 malaria patients (Group 2). The sensitivity of the algorithm in diagnosing malaria was 91% in Group 1 and 71% in Group 2, with specificities of