Haemoglobin changes and risk of anaemia following treatment for uncomplicated falciparum malaria in sub-Saharan Africa (Publications)
BACKGROUND: Anaemia is common in malaria. It is important to quantitate the risk of anaemia and to distinguish factors related to the natural history of disease from potential drug toxicity. METHODS: [...] data analysis based on nine randomized controlled trials of treatments of uncomplicated falciparum malaria from 13 sub-Saharan African countries. Risk factors for reduced haemoglobin (Hb) concentrations and
Natural immune response to <em>Plasmodium vivax </em>alpha-helical coiled coil protein motifs and its association with the risk of <em>P. vivax</em>... (Publications)
selected coiled coil antigens might be good markers of both exposure and acquired immunity to P. vivax malaria, and further preclinical investigation should be performed to determine their potential as P. vivax
Controlled human malaria infection leads to long-lasting changes in innate and innate-like lymphocyte populations (Publications)
clinically silent. To overcome this limitation, we examined blood samples from a controlled human malaria infection (CHMI) study in a Tanzanian cohort, in which volunteers underwent CHMI with a low or high
Bayesian spatio-temporal modeling of mortality in relation to malaria incidence in western Kenya (Publications)
between malaria transmission intensity and all-cause/malaria mortality. This offers a quick and efficient way to monitor malaria burden. Excess mortality estimates indicate that small changes in malaria incidence [...] spatio-temporal survival models to investigate the relation between mortality (all-cause/malaria-specific) and malaria incidence across all age groups. The analysis adjusted for insecticide-treated net (ITN) [...] positive association with malaria-specific mortality in young...
Tracking development assistance and government health expenditures for 35 malaria-eliminating countries: 1990-2017 (Publications)
financier for malaria, providing 96% of the total external funding for malaria in 2013, with vector control interventions being the highest cost driver in all regions. Government expenditure on malaria, while [...] health to the 35 countries actively pursuing malaria elimination. Where possible, development assistance for health (DAH) was categorized by spend on malaria intervention. A diverse set of data points were [...] were used to estimate government health budgets expenditure on malaria,...
Participatory mapping of target areas to enable operational larval source management to suppress malaria vector mosquitoes in Dar es Salaam, Tanzania (Publications)
Half of the population of Africa will soon live in towns and cities where it can be protected from malaria by controlling aquatic stages of mosquitoes. Rigorous but affordable and scaleable methods for mapping [...] identification and inclusion of these key areas, as well as more equal distribution of the workload of malaria control field staff. CONCLUSIONS: The procedure developed enables complete coverage of targeted areas [...] affordable, and requires minimal technical skills. This approach...