Mass mosquito trapping for malaria control in western Kenya: study protocol for a stepped wedge cluster-randomised trial (Publications)
of malaria threaten the efficacy of existing vector control tools used against malaria mosquitoes. The development of odour-baited mosquito traps has led to the possibility of controlling malaria through [...] mass mosquito trapping could be an effective tool for elimination of malaria. If proven to be effective, this novel approach to malaria control would be a valuable addition to the existing strategies of [...] through mass trapping of malaria vectors. Through daily removal trapping against...
Changes in malaria burden and transmission in sentinel sites after the roll-out of long-lasting insecticidal nets in Papua New Guinea (Publications)
exhibits a complex malaria epidemiology due to diversity in malaria parasites, mosquito vectors, human hosts, and their natural environment. Heterogeneities in transmission and burden of malaria at various scales [...] scales are likely to affect the success of malaria control interventions, and vice-versa. This manuscript assesses changes in malaria prevalence, incidence and transmission in sentinel sites following the [...] Diagnosis of malaria infection in humans was done by rapid diagnostic...
A malaria risk map of Kinshasa, Democratic Republic of Congo (Publications)
This study presents the first malaria risk map of Kinshasa, a mega city of roughly 10 million inhabitants and located in a highly endemic malaria zone. Prevalence of malaria, anaemia and reported fever was [...] prevalence for malaria and anaemia was 6.4 % (5.6-7.4) and 65.1 % (63.7-66.6) in 2009, and 17.0 % (15.7-18.3) and 64.2 % (62.6-65.9) in 2011. In two HZs sampled in both surveys, malaria prevalence was [...] BACKGROUND: In Kinshasa, malaria remains a major public health problem but its...
Spatially variable risk factors for malaria in a geographically heterogeneous landscape, western Kenya: an explorative study (Publications)
factors for malaria can give insight into which human and environmental characteristics play important roles in sustaining malaria transmission. METHODS: On Rusinga Island, western Kenya, malaria infection [...] negatively associated with malaria prevalence. DISCUSSION: Identification of risk factors for malaria that vary geographically can provide insight into the local epidemiology of malaria. Examining spatially [...] Combining the data from both surveys, overall malaria prevalence was 24 %....
Stakeholders' opinions and questions regarding the anticipated malaria vaccine in Tanzania (Publications)
accept the malaria vaccine despite the need to continue using insecticide-treated nets (ITNs), while 88.4 % reported that they will accept malaria vaccine even if their children get malaria less often [...] opinions towards malaria vaccine were due to a need for additional malaria prevention strategies and expectations that the vaccine will reduce visits to the health facility, deaths, malaria episodes and [...] BACKGROUND: Within the context of combined interventions, malaria vaccine may...
Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved <em>Plasmodium falciparum</em>... (Publications)
Controlled human malaria infection (CHMI) by mosquito bite has been used to assess new anti-malaria interventions in > 1,500 volunteers since development of methods for infecting mosquitoes by feeding
Hemolysis after oral artemisinin combination therapy for uncomplicated <em>Plasmodium falciparum</em> malaria (Publications)
weeks after treatment of severe malaria with intravenous artesunate have been described. We performed a prospective observational study of patients with uncomplicated malaria to investigate whether posttreatment [...] occurs after oral artemisinin-based combination therapy. Eight of 20 patients with uncomplicated malaria who were given oral artemisinin-based combination therapy met the definition of posttreatment hemolysis [...] g/dL; p = 0.002). These findings indicate a need for increased...
Pregnant women and infants as sentinel populations to monitor prevalence of malaria: results of pilot study in Lake Zone of Tanzania (Publications)
screened for malaria infection using a malaria rapid diagnostic test (RDT) from December 2012 to November 2013, regardless of symptoms. Participants who tested positive were treated for malaria per national [...] BACKGROUND: As malaria control interventions are scaled-up, rational approaches are needed for monitoring impact over time. One proposed approach includes monitoring the prevalence of malaria infection among [...] facility (HF) visits. This pilot explored the feasibility and utility of...
Mapping intra-urban malaria risk using high resolution satellite imagery: a case study of Dar es Salaam (Publications)
of malaria in rapidly growing African urban settlements. The complex and heterogeneous nature of urban malaria requires a better understanding of the spatial and temporal patterns of urban malaria risk [...] localized heterogeneity of malaria transmission and develop a high resolution predictive malaria risk map of Dar es Salaam. RESULTS: Results indicate that the risk of malaria infection varied across the [...] settlements by 2030, the burden of malaria among urban populations in Africa...