Sub-lethal exposure to chlorfenapyr reduces the probability of developing <em>Plasmodium falciparum</em> parasites in surviving Anopheles mosquitoes (Publications)
BACKGROUND: Pyrethroid resistance in the key malaria vectors threatens the success of pyrethroid-treated nets. To overcome pyrethroid resistance, Interceptor(®) G2 (IG2), a 'first-in-class' dual insecticidal [...] the intensity of the P. falciparum infection. This will likely also contribute to the reduction of malaria in communities beyond the direct killing of mosquitoes.
Implementing new health interventions in developing countries: why do we lose a decade or more? (Publications)
We undertook an analysis of the time required to begin implementation of four vaccines and three malaria interventions. We evaluated five milestones for each intervention, and assessed if the milestones [...] implementing any of the vaccines, increasing to an average of only 4% of LICs after 10 years. Each malaria intervention was used by an average of 7% of LICs after five years and 37% after 10 years. Four of
Design, implementation and evaluation of a national campaign to distribute nine million free LLINs to children under five years of age in Tanzania (Publications)
(LLIN) to every child under five years in Tanzania. METHODS: The ITN Cell, a unit within the National Malaria Control Programme (NMCP), coordinated the campaign on behalf of the Ministry of Health and Social [...] mainland Tanzania, the first region being covered separately during an integrated measles immunization/malaria LLIN distribution in August 2008, and was implemented one zone at a time from March 2009 until May
Optimization and validation of multi-coloured capillary electrophoresis for genotyping of <em>Plasmodium falciparum</em> merozoite surface proteins... (Publications)
encoding the merozoite surface proteins 1 and 2 (msp1 and msp2) is well established in the field of malaria research to determine the number and types of concurrent clones in an infection. Genotyping is regarded [...] size ( < 1 bp). More genotypes were detected in mixtures of laboratory lines and blood samples from malaria infected children, compared to gel electrophoresis. The capacity to distinguish recrudescent parasites
The challenge to avoid anti-malarial medicine stock-outs in an area of funding partners: the case of Tanzania (Publications)
introduction of a health facility ACT stock monitoring system using SMS technology by the National Malaria Control Programme in mid 2011 revealed a high frequency of stock-outs of ACT in primary care public [...] both within the country and from the main donor, the Global Fund to Fight AIDS, Tuberculosis and Malaria. Tanzania should invest in strengthening both the supply system and the health information system
Multilocus haplotypes reveal variable levels of diversity and population structure of <em>Plasmodium falciparum</em> in Papua New Guinea, a region of... (Publications)
falciparum on the coast and in the low-lying inland areas. Local heterogeneity in the epidemiology of malaria suggests that parasites from multiple locations will need to be surveyed to define the population [...] variable genetic diversity and population structure of P. falciparum has important implications for malaria control strategies and warrants further fine scale sampling throughout Papua New Guinea
Operational challenges to continuous LLIN distribution: a qualitative rapid assessment in four countries (Publications)
BACKGROUND: The World Health Organization recommends that long-lasting insecticidal nets (LLINs) for malaria prevention should be distributed continuously through antenatal care (ANC) and the expanded programme [...] participants were included (23 in Kenya, 13 in Malawi, 18 in Mali and 16 in Rwanda), drawn from malaria programmes, ANC and EPI programmes, government logistics units, and partner organizations. Interviews
Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery (Publications)
accelerate drug discovery for diseases of poverty, the Medicines for Malaria Venture (MMV) has released box sets of 400 compounds named the Malaria, Pathogen and Stasis Boxes. Here, we screened the Pathogen Box
Impact Stories | Swiss TPH (Page)
https://www.swisstph.ch/fr/impact-stories
research. Read more 22.04.2021 Julia Richter, Swiss Malaria Group World Malaria Day 2021: In the shadows of the COVID-19 pandemic A world without malaria is within reach. At the same time, the COVID-19 pandemic [...] progress in the fight against malaria. This year's World Malaria Day on 25 April 2021 will draw attention to the fact that further efforts are needed to achieve the goal of a malaria-free world. Read more 21 [...] years, much has been invested in malaria prevention and treatment,...
Evaluation of ethnobotanically selected Benin medicinal plants for their in vitro antiplasmodial activity (Publications)
Twenty extracts from nine Benin medicinal plants, traditionally used to treat malaria, were screened for in vitro antiplasmodial activity towards Plasmodium falciparum K1 chloroquine resistant and 3D7