Mycolactone-dependent depletion of endothelial cell thrombomodulin is strongly associated with fibrin deposition in Buruli ulcer lesions (Publications)
A well-known histopathological feature of diseased skin in Buruli ulcer (BU) is coagulative necrosis caused by the Mycobacterium ulcerans macrolide exotoxin mycolactone. Since the underlying mechanism
Bacteria-induced egg hatching differs for <em>Trichuris muris</em> and <em>Trichuris suis</em> (Publications)
BACKGROUND: Eggs of the porcine whipworm Trichuris suis are currently explored in human clinical trials as a treatment of immune-mediated diseases. In this context, only the infective, embryonated egg
Comparability between insecticide resistance bioassays for mosquito vectors: time to review current methodology? (Publications)
BACKGROUND: Insecticides play an integral role in the control of mosquito-borne diseases. With resistance to insecticides on the rise, surveillance of the target population for optimal choice of insec
Toward measuring <em>Schistosoma</em> response to praziquantel treatment with appropriate descriptors of egg excretion (Publications)
BACKGROUND: The control of schistosomiasis emphasizes preventive chemotherapy with praziquantel, which aims at decreasing infection intensity and thus morbidity in individuals, as well as transmission