Comparison of axillary, rectal and tympanic temperature measurements in children admitted with malaria (Publications)
We compared axillary, rectal and tympanic temperatures in children admitted with severe malaria. The axillary temperatures were 0.74 degrees C (95% limits of agreement -0.85 to 2.33 degrees C) less than
The effects of untreated bednets on malaria infection and morbidity on the Kenyan coast (Publications)
protected against both malaria infection and clinical disease compared with children not sleeping under bednets. The study was conducted in Kilifi District, Kenya, during the malaria season (June-August, [...] P = 0.47). When these same children were followed-up during the malaria season, there was evidence of a lower rate of clinical malaria among those that used untreated nets in good condition (adjusted [...] or = 10 years. Data collected from a cross-sectional survey showed evidence of...
Peripheral blood dendritic cells in children with acute <em>Plasmodium falciparum</em> malaria (Publications)
children suffering from acute malaria in Kilifi, Kenya. Comparable percentages of CD83(+) DCs were found in peripheral blood of healthy children and children with malaria. However, the percentage of HLA-DR(+) [...] qualitative and quantitative analysis of these cells in various human diseases. Plasmodium falciparum malaria is characterized by the poor induction of long-lasting protective immune responses. This study, therefore [...] HLA-DR(+) peripheral blood DCs was significantly reduced in...
Accuracy of malaria diagnosis by microscopy, rapid diagnostic test, and PCR methods and evidence of antimalarial overprescription in non-severe... (Publications)
The study was aimed to evaluate the malaria over/underdiagnosis and over/underprescription of antimalarial drugs. Between February and March 2007 blood samples were collected from 336 non-severe febrile [...] Infectious Diseases Lazzaro Spallanzani (INMI), Rome, Italy. As a result of PCR, we identified 26 malaria cases out of 336 (7.7%) patients. Microscopy and RDT accuracies were 93.5% and 97.6%, respectively [...] were 29.3% and 30.8%, respectively. On-field training, clinical management of...
Comparison of the Paracheck-Pf test with microscopy, for the confirmation of <em>Plasmodium falciparum</em> malaria in Tanzania (Publications)
Tanzania, four of which experience frequent malaria outbreaks. The aim was to verify whether Paracheck-Pf could be a reliable tool for the confirmation of malaria outbreaks in such areas. The overall measurements [...] detection of malaria outbreaks. The cost of the assay (U.S.$0.62/test at the time of the present study) is sufficiently low that its routine use in the confirmation of P. falciparum malaria might also be [...] positive predictive value of 88.9%, and a negative predictive value of...
Indoors man-biting mosquitoes and their implication on malaria transmission in Mpwapwa and Iringa Districts, Tanzania (Publications)
the two districts was infected with malaria sporozoites. Despite low mosquito densities and absence of infective mosquitoes in our study, the two districts are malaria epidemic prone, thus a continuous [...] outbreak. Further longitudinal studies are required to determine the transmission potential of the malaria mosquitoes in the two districts
