Combining sociological, economic and epidemiological evidence to target malaria interventions in Papua New Guinea and beyond (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/combining-sociological-economic-and-epidemiological-evidence-to-target-malaria-interventions-in-papua-new-guinea-and-beyond
interventions. However, current recommendations focus exclusively on stratification by malaria risk. Yet, malaria is multi-factorial and the impact of interventions in a given setting also depends on [...] conceptual framework for a multi-dimensional malaria stratification beyond mere epidemiological indicators. Papua New Guinea (PNG) with its complex malaria epidemiology serves as a model country. Project [...] To improve the (cost-) effectiveness of malaria control and accelerate progress...
Environmental, Social, Economic and Health Impact Assessment (ESHIA) for a Field Study of a Self-Limiting Nondrive Strain of Genetically Modified... (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/environmental-social-economic-and-health-impact-assessment-eshia-for-a-field-study-of-a-self-limiting-nondrive-strain-of-genetically-modified-mosquitoes-on-behalf-of-target-malaria
Genetically modified mosquitoes (GMMs) represent great potential for malaria control in the future. Target Malaria – a vector control research alliance based at the Imperial College in London – aims to [...] develop genetic technologies to modify mosquitoes with the ultimate goal to reduce malaria transmission. Target Malaria uses a three-phased approach in this 170-million project funded by the Bill and Melinda
Towards Elimination of Malaria in Tanzania (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/towards-elimination-of-malaria-in-tanzania
Malaria and poverty entertain a close relationship through historical times. Past studies have abundantly documented the benefits of malaria control on economic development and human well-being, and as [...] of malaria across the country declined, the heterogeneity in transmission greatly increased. At present, some areas in Tanzania remain with a very high transmission and hence with a high malaria burden [...] and risk stratification followed by decentralized malaria control planning has...
Mathematical models to define new malaria immunotherapies and interventions to meet public health needs (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/mathematical-models-to-define-new-malaria-immunotherapies-and-interventions-to-meet-public-health-needs
progress in fighting malaria, there remains a need for new antimalarial interventions to protect children and other vulnerable populations who experience the highest burden of malaria. Developing new in [...] from academia, product development partners, and representatives from malaria-endemic countries. Our focus is on next-generation malaria vaccines, monoclonal antibodies, and new chemoprevention antimalarials
Provision of a Scoping Study for a Strategic Environmental Assessment (SEA) on behalf of Target Malaria (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/provision-of-a-scoping-study-for-a-strategic-environmental-assessment-sea-on-behalf-of-target-malaria
Genetically modified mosquitoes represent great potential for malaria control. Any future application of gene drive mosquitoes for malaria control will require many elements, including policy action, [...] to suppress populations of malaria vector mosquitoes. The assessments main objectives are to: (i) raise awareness amongst policy makers of genetic control tools for malaria using gene drives (ii) develop [...] gene drive (the action) and subsequent reduction of malaria (the desired effect)...
Spatio-temporal modelling to assess the impact of climate change on the burden of malaria and to support early warning systems (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/spatio-temporal-modelling-to-assess-the-impact-of-climate-change-on-the-burden-of-malaria-and-to-support-early-warning-systems
climate variability, land use, malaria vector control coverage and socio-economic factors to changes in malaria incidence and mortality; (ii) develop stochastic metapopulation malaria transmission models which [...] statistical models to forecast malaria; (iv) evaluate the effects of environmental vector-control with microbial larvicides on the burden of malaria; and (v) project future malaria burden based on scenarios [...] changes, malaria interventions and socioeconomic effects, which are...
Papua New Guinea National Malaria Control Programme Evaluation and Operational Research 2021 to 2023 (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/papua-new-guinea-national-malaria-control-programme-evaluation-and-operational-research-2021-to-2023
exhibits a complex malaria epidemiology with marked heterogeneity in malaria transmission. With financial support from the Global Fund to Fight AIDS, Tuberculosis and Malaria, the National Malaria Control Program [...] across PNG to assess quality of malaria case management. Activity 2: a national Malaria Indicator Survey (MIS) to track progress in malaria intervention coverage and malaria prevalence on national and regional [...] changing malaria epidemiology in PNG (including aspects related...
Modelling support to decision-making for malaria control in Benin (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/modelling-support-to-decision-making-for-malaria-control-in-benin
interact with the NMCP to gather a deeper understanding of the past malaria burden and control efforts. We then calibrate OpenMalaria , the malaria transmission simulation platform developed in-house, to quantify [...] National Malaria Control Program (NMCP) since 2018. The NMCP is currently updating its National Strategic Plan (NSP) for the period 2024-2026. This plan will guide the strategy and tools for malaria control [...] more impactful between administering seasonal malaria...
Deciphering Environmental Sensing in Malaria Parasites (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/deciphering-environmental-sensing-in-malaria-parasites
The Malaria Host Interactions Unit (MHIU) is studying the molecular interface between malaria parasites and their human host. Recent findings revealed the existence of intimate links between parasite [...] inducing specific transcriptional responses. This capability is surprising in light of the fact that malaria parasites have lost canonical nutrient sensing pathways present in other eukaryotic organisms. With
Global Malaria Technical & Training Support Package, Phase 3 (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/global-malaria-technical-training-support-package-phase-3
global malaria control and elimination by shaping global and national malaria control and elimination policies, and ultimately to reduce the malaria burden and to increase the number of malaria-free zones [...] and national malaria strategies. Background Thanks to the scale-up of effective malaria vector control tools such as insecticide-treated mosquito nets, diagnostics and medicines, malaria mortality has [...] Back Malaria action plan, aligned with the 2016-2030 timeline of the Sustainable...