The importance of mosquito behavioural adaptations to malaria control in Africa (Publications)
could have significant impacts on the effectiveness of malaria control. We propose seven recommendations to improve understanding of resistance in malaria vectors. Determining the public health impact of p [...] drug therapies, indoor residual spraying (IRS), and better health infrastructure, has helped reduce malaria in many African countries for the first time in a generation. However, insecticide resistance in [...] e resistance is an urgent priority if we are to maintain the significant...
Safety and immunogenicity of a three-component blood-stage malaria vaccine (MSP1, MSP2, RESA) against <em>Plasmodium falciparum</em> in Papua New... (Publications)
Combination B is a malaria vaccine that comprises recombinant Plasmodium falciparum (P. falciparum) blood-stage proteins MSP1, MSP2 and RESA, formulated with the adjuvant Montanide ISA 720. A phase I-IIb [...] nor increased after pre-treatment with SP and pre-treatment is not advisable in future trials of malaria vaccines, at least for those including blood-stage antigens
Malaria mapping using transmission models: application to survey data from Mali (Publications)
to age-specific malaria prevalence. The approach makes more efficient use of the available data than do previous malaria mapping methods, and it produces highly plausible maps of malaria distribution [...] Geographic mapping of the distribution of malaria is complicated by the limitations of the available data. The most widely available data are from prevalence surveys, but these surveys are generally carried [...] approach to the analysis of survey data from Mali, collected in 1965-1998,...
Malaria and casual sex: what travelers know and how they behave (Publications)
Results: Compliance with chemosuppressive regimen for malaria was 87%. Well-informed travelers did not protect themselves more efficiently against malaria. The efficacy of a given intervention was found to [...] Background: Travelers to the tropics have been reported to comply poorly with recommendations regarding malaria and AIDS. This study addresses the problem of influencing travelers' behavior through different [...] implications of "sex tourism" and the possibility of participating in a...
Multiplex real-time PCR for the diagnosis of malaria: correlation with microscopy (Publications)
Abstract Malaria is generally diagnosed by microscopy and rapid antigen testing. Molecular methods become more widely used. In the present study, the contribution of a quantitative multiplex malaria PCR was
Intermittent treatment for malaria and anaemia control at time of routine vaccinations in Tanzania infants: a randomised, placebo-controlled trial (Publications)
BACKGROUND: Clinical malaria and severe anaemia are major causes of paediatric hospital admission and death in many malaria-endemic settings. In the absence of an effective and affordable vaccine, control [...] were not affected by the intervention. INTERPRETATION: This new approach to malaria control reduced the rate of clinical malaria and severe anaemia by delivering an available and affordable drug through [...] assess the efficacy and safety of intermittent sulphadoxine-pyrimethamine...