Methodological framework for assessing malaria risk associated with climate change in Côte d'Ivoire (Publications)
Malaria is the leading cause of morbidity among children under five years of age and pregnant women in Côte d'Ivoire. We assessed the geographical distribution of its risk in all climatic zones of the [...] main driving components affecting the risk: Hazard, exposure and vulnerability. Considering the malaria impact chain, various variables were identified for each of the risk factors and for each variable [...] or equatorial (tropical transition regime) in the North and the mountainous (humid)...
A review of selective indoor residual spraying for malaria control (Publications)
BACKGROUND: Indoor residual spraying (IRS) is one of the most effective malaria control tools. However, its application has become limited to specific contexts due to the increased costs of IRS products [...] tive spray targeted to particular areas/surfaces of dwellings-has been proposed to maintain the malaria control and resistance-management benefits of IRS while decreasing the costs of the intervention [...] mosquitoes and (2) studies that evaluated the impact of selective spraying on...
Slow clearance of histidine-rich protein-2 in Gabonese with uncomplicated malaria (Publications)
Malaria rapid diagnostic tests (RDTs), which detect Plasmodium falciparum (Pf)-specific histidine-rich protein-2 (HRP2), have increasing importance for the diagnosis and control of malaria, especially [...] RDT-based assessment following a malaria treatment for weeks. A better understanding of the HRP2 clearance dynamics is critical for guiding the diagnosis of malaria when relying on RDTs. IMPORTANCE: Detecting [...] determine the long-term kinetic of HRP2-levels in peripheral blood after...
The impact of soil transmitted helminth on malaria clinical presentation and treatment outcome: a case control study among children in Bagamoyo... (Publications)
been documented between Plasmodium and STH. This study investigated the impact of STH on clinical malaria presentation and treatment outcome. METHODS: A matched case control study with a semi longitudinal [...] areas of Bagamoyo, coastal region of Tanzania. Cases were children with uncomplicated and severe malaria enrolled from the health facilities while controls were children with asymptomatic Plasmodium parasitemia [...] regression analysis there was a tendency for a protective effect of STH...
Embedded-deep-learning-based sample-to-answer device for on-site malaria diagnosis (Publications)
digital image transmission. This method can set a new paradigm for on-site malaria diagnosis. The miLab™ algorithm for malaria detection achieved a total accuracy of 98.86% for infected red blood cell (RBC) [...] Improvements in digital microscopy are critical for the development of a malaria diagnosis method that is accurate at the cellular level and exhibits satisfactory clinical performance. Digital microscopy [...] 92.21%. Based on these results, miLab™ can become a reliable and efficient...
The influence of malaria control interventions and climate variability on changes in the geographical distribution of parasite prevalence in Kenya... (Publications)
The burden of malaria in Kenya was showing a declining trend, but appears to have reached a plateau in recent years. This study estimated changes in the geographical distribution of malaria parasite risk [...] contribution of malaria control interventions and climatic/ environmental factors to these changes. METHODS: Bayesian geostatistical models were used to analyse the Kenyan 2015 and 2020 Malaria Indicator Survey [...] coverage of most malaria indicators related to Insecticide Treated Nets...
Empowering rural communities for effective larval source management: a small-scale field evaluation of a community-led larviciding approach to control... (Publications)
source management, particularly larviciding, is mainly implemented in urban settings to control malaria and other mosquito-borne diseases. In Tanzania, the government has recently expanded larviciding [...] characterize and target larval habitats of Anopheles funestus mosquitoes, the dominant vector of malaria transmission in south-eastern Tanzania. Methods: A mixed-methods study was used. First, intervie [...] community-based volunteers were trained to identify and characterize aquatic habitats...
Forecasting malaria dynamics based on causal relations between control interventions, climatic factors, and disease incidence in western Kenya (Publications)
drivers and investigate their effects, interaction strength, and suitability ranges on malaria incidence. Monthly malaria cases were collected at St. Elizabeth Lwak Mission Hospital. Intervention coverage [...] Short-term forecasting of malaria incidence was performed using state-space reconstruction. RESULTS: We observed causal links between climatic drivers, bed net use, and malaria incidence. LSTD lagged over [...] BACKGROUND: Malaria remains one of the deadliest diseases worldwide,...